Homo sapiens

Kidney loop of henle thick ascending limb epithelial cell Kidney interstitial fibroblast Leukocyte Kidney proximal convoluted tubule epithelial cell Podocyte Kidney collecting duct principal cell Macrophage Blood vessel smooth muscle cell Endothelial cell Kidney collecting duct intercalated cell Mesangial cell Kidney granular cell Kidney distal convoluted tubule epithelial cell

Cortex of kidney

62-year-old stage

Normal

Male

Slide-seqv2

Homo sapiens

Oligodendrocyte Natural killer cell Astrocyte T cell Medial ganglionic eminence derived interneuron Microglial cell Oligodendrocyte precursor cell B cell Neuron Pericyte Committed oligodendrocyte precursor Monocyte Cerebral cortex neuron Intratelencephalic-projecting glutamatergic cortical neuron Vascular associated smooth muscle cell Hippocampal ca1-3 neuron Endothelial cell Caudal ganglionic eminence derived interneuron Dentate gyrus granule cell Thalamic excitatory neuron Central nervous system macrophage Midbrain-derived inhibitory neuron Fibroblast Lamp5 lhx6 neuron Mammillary body neuron

Subthalamic nucleus

42-year-old stage 29-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Retinal ganglion cell Retinal bipolar neuron Microglial cell Retinal blood vessel endothelial cell Retinal cone cell Macroglial cell Amacrine cell Retina horizontal cell Retinal rod cell

Macula lutea Peripheral region of retina

68-year-old stage 86-year-old stage 71-year-old stage

Normal

Male

10x 3' v3

Cell

Mus musculus

Kidney loop of henle thick ascending limb epithelial cell Kidney interstitial fibroblast Leukocyte Kidney proximal convoluted tubule epithelial cell Macula densa epithelial cell Podocyte Kidney collecting duct principal cell Macrophage Blood vessel smooth muscle cell Endothelial cell Kidney collecting duct intercalated cell Mesangial cell Kidney granular cell Kidney distal convoluted tubule epithelial cell

Kidney

13-week-old stage

Normal

Male

Slide-seqv2

Homo sapiens

Oligodendrocyte Astrocyte T cell Medial ganglionic eminence derived interneuron Pvalb chandelier gabaergic interneuron Microglial cell Oligodendrocyte precursor cell Neuron Ependymal cell Pericyte Committed oligodendrocyte precursor Monocyte Eccentric medium spiny neuron Cerebellar inhibitory gabaergic interneuron Cerebellar granule cell Intratelencephalic-projecting glutamatergic cortical neuron Vascular associated smooth muscle cell Sst chodl gabaergic interneuron Endothelial cell Amygdala excitatory neuron Caudal ganglionic eminence derived interneuron Medium spiny neuron Thalamic excitatory neuron Midbrain-derived inhibitory neuron Fibroblast Lamp5 lhx6 neuron Mammillary body neuron

Hypothalamus

42-year-old stage 29-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Malignant cell Cd8-positive, alpha-beta t cell Epithelial cell Fibroblast Myeloid cell Cd4-positive helper t cell

Kidney

61-year-old stage

Renal cell carcinoma

Male

Slide-seqv2

Homo sapiens

Retinal ganglion cell Retinal bipolar neuron Microglial cell Obsolete somatic cell Retinal cone cell Mueller cell Amacrine cell Retinal rod cell

Retinal neural layer

42-year-old stage 80-year-old stage 53-year-old stage

Normal

Female Male

10x genomics v2

Homo sapiens

Naive b cell Memory b cell Igg plasmablast Iga plasmablast Transitional stage b cell Plasmablast

Blood

62-year-old stage 38-year-old stage 54-year-old stage 49-year-old stage Fourth decade stage 59-year-old stage 46-year-old stage 68-year-old stage Seventh decade stage 82-year-old stage Fifth decade stage 60-year-old stage 75-year-old stage 63-year-old stage 61-year-old stage 48-year-old stage 39-year-old stage 27-year-old stage 36-year-old stage Adult stage 78-year-old stage 67-year-old stage Sixth decade stage 80 year-old and over stage 47-year-old stage Eighth decade stage 84-year-old stage Third decade stage 53-year-old stage 29-year-old stage 37-year-old stage 73-year-old stage 70-year-old stage

Covid-19 Normal

Female Male

10x 3' v2 10x 3' v3 Seq-well

Cell

Homo sapiens

Kidney loop of henle thick ascending limb epithelial cell Renal principal cell Leukocyte Kidney capillary endothelial cell Podocyte Parietal epithelial cell Epithelial cell of proximal tubule Renal beta-intercalated cell Mesangial cell Renal alpha-intercalated cell Kidney connecting tubule epithelial cell Fibroblast Kidney distal convoluted tubule epithelial cell

Cortex of kidney

62-year-old stage 54-year-old stage 61-year-old stage 52-year-old stage 50-year-old stage

Normal

Female Male

10x 5' v1

Nucleus

Mus musculus

Kidney loop of henle thick ascending limb epithelial cell Kidney interstitial fibroblast Leukocyte Kidney proximal convoluted tubule epithelial cell Macula densa epithelial cell Podocyte Kidney collecting duct principal cell Macrophage Blood vessel smooth muscle cell Endothelial cell Kidney collecting duct intercalated cell Mesangial cell Kidney distal convoluted tubule epithelial cell

Kidney

6-month-old stage

Autosomal dominant polycystic kidney disease

Male

Slide-seqv2

Homo sapiens

Cd4-positive helper t cell

Normal

10x scatac-seq

Mus musculus

Transit amplifying cell of small intestine Enterocyte of epithelium of small intestine Small intestine goblet cell Stem cell Enteroendocrine cell of small intestine Paneth cell of epithelium of small intestine Tuft cell of small intestine

Small intestine

3-month-old stage

Normal

Female Male

10x 3' v3

Cell