Homo sapiens

Kidney loop of henle thick ascending limb epithelial cell Kidney interstitial fibroblast Leukocyte Kidney proximal convoluted tubule epithelial cell Kidney collecting duct principal cell Macrophage Blood vessel smooth muscle cell Endothelial cell Kidney collecting duct intercalated cell Kidney distal convoluted tubule epithelial cell

Renal medulla

50-year-old stage

Normal

Male

Slide-seqv2

Homo sapiens

Kidney loop of henle thick ascending limb epithelial cell Kidney interstitial fibroblast Leukocyte Kidney collecting duct principal cell Macrophage Blood vessel smooth muscle cell Endothelial cell Kidney collecting duct intercalated cell Kidney distal convoluted tubule epithelial cell

Renal medulla

56-year-old stage

Normal

Male

Slide-seqv2

Homo sapiens

Club-like cell of the urethral epithelium Prostate neuroendocrine cell Epithelial cell of prostate Basal cell of prostate epithelium Luminal cell of prostate epithelium Ciliated epithelial cell

Prostate gland

62-year-old stage 54-year-old stage 59-year-old stage 64-year-old stage 46-year-old stage 68-year-old stage 60-year-old stage 75-year-old stage 63-year-old stage 61-year-old stage 72-year-old stage 45-year-old stage 69-year-old stage 70-year-old stage 71-year-old stage

Prostatic acinar adenocarcinoma

Male

10x 3' v3

Cell

Homo sapiens

Endothelial cell of artery Blood vessel endothelial cell Pulmonary artery endothelial cell Vein endothelial cell

Lung Trachea Upper lobe of left lung Lower lobe of left lung Bronchus

66-year-old stage 59-year-old stage 64-year-old stage Seventh decade stage 75-year-old stage 35-year-old stage Sixth decade stage 58-year-old stage 29-year-old stage

Normal

Female Male

10x 3' v2 10x 5' transcription profiling 10x 3' v3

Cell Nucleus

Homo sapiens

Thymic fibroblast type 2 Thymic fibroblast type 1 Fibroblast

Thymus

14th week post-fertilization stage 10-month-old stage 15th week post-fertilization stage 6-month-old stage 20th week post-fertilization stage 24th week post-fertilization stage 2-year-old stage 13th week post-fertilization stage 12th week post-fertilization stage 18th week post-fertilization stage 17th week post-fertilization stage 3-month-old stage Newborn stage (0-28 days)

Normal

Female Male

10x 5' v2 10x 3' v2 10x 5' v1 10x 3' v3

Cell

Homo sapiens

Near-projecting glutamatergic cortical neuron

Middle temporal gyrus

43-year-old stage 68-year-old stage 88-year-old stage 86-year-old stage 82-year-old stage 83-year-old stage 60-year-old stage 75-year-old stage 80-year-old stage 77-year-old stage Adult stage 89-year-old stage 78-year-old stage 72-year-old stage 80 year-old and over stage 81-year-old stage 87-year-old stage 84-year-old stage 65-year-old stage 85-year-old stage 50-year-old stage 29-year-old stage 69-year-old stage 70-year-old stage

Dementia Normal

Female Male

10x multiome 10x 3' v3

Nucleus

Mus musculus

Kidney loop of henle thick ascending limb epithelial cell Kidney interstitial fibroblast Leukocyte Kidney proximal convoluted tubule epithelial cell Kidney collecting duct principal cell Macrophage Blood vessel smooth muscle cell Endothelial cell Kidney collecting duct intercalated cell Kidney distal convoluted tubule epithelial cell

Kidney

6-month-old stage

Autosomal dominant polycystic kidney disease

Male

Slide-seqv2

Mus musculus

Basal cell of epidermis Keratinocyte Langerhans cell

Tongue

4-week-old stage 20-month-old stage and over 18-month-old stage 3-month-old stage

Normal

Female Male

10x 3' v2

Cell

Homo sapiens

Natural killer cell Innate lymphoid cell T cell B cell Theca cell Smooth muscle cell Stromal cell of ovary Endothelial cell Granulosa cell

Ovary

Adult stage

Normal

Female

10x 3' v2

Cell

Homo sapiens

Myoepithelial cell Glandular secretory epithelial cell Memory t cell Luminal endometrial multiciliated epithelial cell Epithelial cell

Myometrium Endometrium

32-year-old stage 31-year-old stage 28-year-old stage 26-year-old stage Young adult stage 23-year-old stage 29-year-old stage 37-year-old stage

Normal

Female

10x 3' v2 10x 3' v3

Cell

Homo sapiens

Non-myelinating schwann cell Myelinating schwann cell Tendon cell Fibroblast of the aortic adventitia Fibroblast Perineurial cell

Intercostal muscle

Fourth decade stage Seventh decade stage Young adult stage Sixth decade stage Eighth decade stage Third decade stage

Normal

Female Male

10x 3' v2 10x 3' v3

Cell

Homo sapiens

Retinal ganglion cell Off parasol ganglion cell On parasol ganglion cell

Fovea centralis Macula lutea Macula lutea proper Peripheral region of retina

62-year-old stage 43-year-old stage 32-year-old stage 66-year-old stage 21-year-old stage 34-year-old stage 30-year-old stage 64-year-old stage 68-year-old stage 88-year-old stage 86-year-old stage 83-year-old stage 60-year-old stage 75-year-old stage 77-year-old stage 74-year-old stage 63-year-old stage 76-year-old stage 27-year-old stage 78-year-old stage 72-year-old stage Prime adult stage 67-year-old stage 47-year-old stage 81-year-old stage 52-year-old stage Eighth decade stage 84-year-old stage 65-year-old stage 85-year-old stage 60-79 year-old stage 69-year-old stage 73-year-old stage Late adult stage 90 year-old and over stage 71-year-old stage

Normal

Female Male

10x 3' v3

Nucleus