Microcebus murinus

Natural killer cell Erythroid lineage cell Erythroid progenitor cell B cell Conventional dendritic cell Neutrophil Monocyte Platelet Mature nk t cell Cd4-positive, alpha-beta t cell Cd8-positive, alpha-beta t cell Capillary endothelial cell Hematopoietic precursor cell Basophil Epithelial cell Plasma cell Megakaryocyte progenitor cell Myeloid cell Mesothelial cell

Blood

Post-juvenile adult stage

Normal

Female Male

10x 3' v2 Smart-seq2

Cell

Mus musculus

Neuron associated cell Multiciliated ependymal cell Deuterosomal cell Radial glial cell

Multiciliated ependymal cell

Theiler stage 27

Normal

10x 3' v3

Cell

Sus scrofa domesticus

Pancreatic d cell Type b pancreatic cell Pancreatic pp cell Pancreatic a cell

Islet of langerhans

Prime adult stage

Normal

Female

10x 3' v2

Cell

Homo sapiens

Dopaminergic neuron

Substantia nigra pars compacta

49-year-old stage 91-year-old stage 82-year-old stage 83-year-old stage 75-year-old stage 92-year-old stage 74-year-old stage 76-year-old stage 89-year-old stage 78-year-old stage 79-year-old stage 90-year-old stage 70-year-old stage

Parkinson disease Lewy body dementia Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

T cell Malignant cell Macrophage Blood vessel smooth muscle cell Blood vessel endothelial cell Fibroblast

Axilla

37-year-old stage

Breast cancer

Female

Slide-seqv2

Homo sapiens

Natural killer cell Innate lymphoid cell T cell Epithelial fate stem cell Regulatory t cell B cell Adventitial cell Pericyte Endothelial cell of lymphatic vessel Neutrophil Monocyte Mature nk t cell Cd4-positive, alpha-beta t cell Myofibroblast cell Macrophage Myeloid dendritic cell Intermediate monocyte Cd8-positive, alpha-beta t cell Vascular associated smooth muscle cell Endothelial cell Granulocyte Epithelial cell of uterus Myometrial cell Ciliated epithelial cell Fibroblast Skeletal muscle satellite stem cell Plasma cell Mast cell

Uterus Myometrium Endometrium

38-year-old stage 45-year-old stage

Normal

Female

Smart-seq2 10x 3' v3

Cell

Homo sapiens

Oligodendrocyte Oligodendrocyte precursor cell Committed oligodendrocyte precursor

Cervical spinal cord white matter White matter of cerebellum Brodmann (1909) area 4

34-year-old stage 42-year-old stage 74-year-old stage 63-year-old stage 61-year-old stage 39-year-old stage 72-year-old stage 44-year-old stage 45-year-old stage 37-year-old stage 73-year-old stage 40-year-old stage 71-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Mus musculus

Kidney loop of henle thick ascending limb epithelial cell Kidney interstitial fibroblast Leukocyte Kidney proximal convoluted tubule epithelial cell Podocyte Kidney collecting duct principal cell Macrophage Blood vessel smooth muscle cell Endothelial cell Kidney collecting duct intercalated cell Mesangial cell Kidney granular cell Kidney distal convoluted tubule epithelial cell

Kidney

6-month-old stage

Normal

Male

Slide-seqv2

Mus musculus

Kidney loop of henle thick ascending limb epithelial cell Kidney interstitial fibroblast Leukocyte Kidney proximal convoluted tubule epithelial cell Macula densa epithelial cell Podocyte Kidney collecting duct principal cell Macrophage Blood vessel smooth muscle cell Endothelial cell Kidney collecting duct intercalated cell Mesangial cell Kidney granular cell Kidney distal convoluted tubule epithelial cell

Kidney

13-week-old stage

Diabetic kidney disease

Male

Slide-seqv2

Mus musculus

Kidney proximal straight tubule epithelial cell Natural killer cell Kidney loop of henle thick ascending limb epithelial cell Tuft cell T cell Leukocyte Kidney capillary endothelial cell B cell Plasmatocyte Kidney cell Kidney proximal convoluted tubule epithelial cell Lymphocyte Epithelial cell of proximal tubule Kidney collecting duct principal cell Macrophage Kidney loop of henle ascending limb epithelial cell Mesangial cell Fibroblast Kidney cortex artery cell Kidney distal convoluted tubule epithelial cell Plasma cell Kidney collecting duct epithelial cell Fenestrated endothelial cell

Kidney

4-week-old stage 20-month-old stage and over 18-month-old stage 3-month-old stage

Normal

Female Male

10x 3' v2

Cell

Homo sapiens

Memory b cell Plasmablast

Tonsil

3-year-old stage 5-year-old stage 6-year-old stage 9-year-old stage

Normal

Female Male

10x 3' v2 10x 5' v1

Cell

Homo sapiens

Oligodendrocyte Natural killer cell Astrocyte Purkinje cell Bergmann glial cell T cell Medial ganglionic eminence derived interneuron Microglial cell Oligodendrocyte precursor cell B cell Neuron Ependymal cell Pericyte Committed oligodendrocyte precursor Monocyte Cerebellar inhibitory gabaergic interneuron Cerebellar granule cell Intratelencephalic-projecting glutamatergic cortical neuron Vascular associated smooth muscle cell Endothelial cell Caudal ganglionic eminence derived interneuron Central nervous system macrophage Midbrain-derived inhibitory neuron Fibroblast Unipolar brush cell

Inferior olivary complex

42-year-old stage 50-year-old stage 29-year-old stage

Normal

Male

10x 3' v3

Nucleus