Mus musculus

Endothelial cell Kidney interstitial fibroblast Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney collecting duct principal cell Kidney loop of henle thick ascending limb epithelial cell Kidney proximal convoluted tubule epithelial cell

Kidney

6-month-old stage

Autosomal dominant polycystic kidney disease

Male

Slide-seqv2

Homo sapiens

Endothelial cell Microglial cell Mueller cell Astrocyte

Peripheral region of retina Fovea centralis

69-year-old stage 65-year-old stage 53-year-old stage 74-year-old stage 64-year-old stage 60-year-old stage 78-year-old stage

Normal

Female Male

10x 3' v3 10x 3' v2

Cell

Microcebus murinus

Neutrophil Natural killer cell Erythroid progenitor cell Mature nk t cell Hematopoietic precursor cell Cd8-positive, alpha-beta t cell Platelet Erythroid lineage cell Capillary endothelial cell Epithelial cell Megakaryocyte progenitor cell Myeloid cell Plasma cell Cd4-positive, alpha-beta t cell Mesothelial cell B cell Monocyte Basophil Conventional dendritic cell

Blood

Post-juvenile adult stage

Normal

Female Male

Smart-seq2 10x 3' v2

Cell

Microcebus murinus

Mus musculus

Multiciliated ependymal cell Deuterosomal cell Radial glial cell Neuron associated cell

Multiciliated ependymal cell

Theiler stage 27

Normal

10x 3' v3

Cell

Sus scrofa domesticus

Pancreatic pp cell Pancreatic a cell Pancreatic d cell Type b pancreatic cell

Islet of langerhans

Prime adult stage

Normal

Female

10x 3' v2

Cell

Homo sapiens

Dopaminergic neuron

Substantia nigra pars compacta

75-year-old stage 91-year-old stage 89-year-old stage 92-year-old stage 82-year-old stage 90-year-old stage 74-year-old stage 49-year-old stage 70-year-old stage 78-year-old stage 76-year-old stage 79-year-old stage 83-year-old stage

Parkinson disease Normal Lewy body dementia

Female Male

10x 3' v3

Nucleus

Homo sapiens

T cell Blood vessel endothelial cell Blood vessel smooth muscle cell Macrophage Malignant cell Fibroblast

Axilla

37-year-old stage

Breast cancer

Female

Slide-seqv2

Homo sapiens

T cell Neutrophil Granulocyte Natural killer cell Endothelial cell of lymphatic vessel Endothelial cell Mature nk t cell Mast cell Cd8-positive, alpha-beta t cell Myometrial cell Intermediate monocyte Myeloid dendritic cell Macrophage Innate lymphoid cell Regulatory t cell Plasma cell Cd4-positive, alpha-beta t cell Epithelial cell of uterus Ciliated epithelial cell B cell Pericyte Skeletal muscle satellite stem cell Adventitial cell Monocyte Vascular associated smooth muscle cell Myofibroblast cell Epithelial fate stem cell Fibroblast

Uterus Endometrium Myometrium

38-year-old stage 45-year-old stage

Normal

Female

Smart-seq2 10x 3' v3

Cell

Homo sapiens

Oligodendrocyte precursor cell Oligodendrocyte Committed oligodendrocyte precursor

Cervical spinal cord white matter Brodmann (1909) area 4 White matter of cerebellum

37-year-old stage 34-year-old stage 42-year-old stage 71-year-old stage 61-year-old stage 39-year-old stage 44-year-old stage 72-year-old stage 74-year-old stage 45-year-old stage 63-year-old stage 73-year-old stage 40-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Mus musculus

Podocyte Endothelial cell Kidney interstitial fibroblast Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney granular cell Kidney collecting duct principal cell Kidney loop of henle thick ascending limb epithelial cell Mesangial cell Kidney proximal convoluted tubule epithelial cell

Kidney

6-month-old stage

Normal

Male

Slide-seqv2

Mus musculus

Podocyte Endothelial cell Kidney interstitial fibroblast Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney granular cell Kidney collecting duct principal cell Kidney loop of henle thick ascending limb epithelial cell Macula densa epithelial cell Mesangial cell Kidney proximal convoluted tubule epithelial cell

Kidney

13-week-old stage

Diabetic kidney disease

Male

Slide-seqv2