Homo sapiens

Vascular leptomeningeal cell Oligodendrocyte precursor cell Oligodendrocyte Macrophage Hippocampal pyramidal neuron Smooth muscle cell of the brain vasculature Hippocampal astrocyte Mature microglial cell Vascular associated smooth muscle cell Ependymal cell Pericyte Endothelial cell Hippocampal granule cell Hippocampal interneuron T cell

Hippocampal formation

79-year-old stage 50-year-old stage 60-year-old stage 44-year-old stage 48-year-old stage 40-year-old stage 37-year-old stage 54-year-old stage 51-year-old stage 42-year-old stage 24-year-old stage 26-year-old stage 29-year-old stage

Normal

Female Male

10x 3' v3 10x 3' v2

Nucleus

Homo sapiens

Pro-b cell Cd22-positive, cd38-low small pre-b cell Common myeloid progenitor Group 1 innate lymphoid cell Innate lymphoid cell Megakaryocyte progenitor cell Cd4-positive, alpha-beta t cell Large pre-b-ii cell Macrophage Mature b cell Granulocyte monocyte progenitor cell Late pro-b cell Alveolar type 1 fibroblast cell Mast cell Megakaryocyte-erythroid progenitor cell Cd16-negative, cd56-bright natural killer cell, human Erythroid lineage cell Fraction a pre-pro b cell Neutrophil Monocyte Megakaryocyte Cd14-positive monocyte Immature b cell Granulocyte Group 3 innate lymphoid cell, human Early lymphoid progenitor Conventional dendritic cell Fibroblast Endothelial cell Pro-t cell Cd8-positive, alpha-beta t cell Group 2 innate lymphoid cell Lung pericyte Dendritic cell Regulatory t cell Plasmacytoid dendritic cell Myelocyte Cd14-low, cd16-positive monocyte Precursor b cell Alveolar adventitial fibroblast Early pro-b cell Smooth muscle cell Epithelial cell of distal tubule Lung secretory cell Natural killer cell Hematopoietic multipotent progenitor cell Ciliated cell Cd16-positive, cd56-dim natural killer cell, human

Lung

9th week post-fertilization stage 13th week post-fertilization stage 12th week post-fertilization stage 10th week post-fertilization stage Carnegie stage 22 11th week post-fertilization stage 21st week post-fertilization stage 20th week post-fertilization stage 17th week post-fertilization stage 15th week post-fertilization stage 22nd week post-fertilization stage Carnegie stage 19 Carnegie stage 13 14th week post-fertilization stage 16th week post-fertilization stage 18th week post-fertilization stage Carnegie stage 23 Carnegie stage 20 Carnegie stage 16

Normal

Female Male

10x 5' v1 10x 5' transcription profiling 10x 3' v2

Cell

Homo sapiens

Astrocyte Oligodendrocyte Lymphocyte Malignant cell Pericyte Endothelial cell Neuron Myeloid cell

Glioblastoma

10x 5' v3

Homo sapiens

Myeloid lineage restricted progenitor cell Naive b cell Igg plasma cell T-helper 2 cell Cd4-positive, alpha-beta t cell Class switched memory b cell Platelet Cd34-positive, cd38-negative hematopoietic stem cell Iga plasma cell Naive thymus-derived cd4-positive, alpha-beta t cell Effector cd8-positive, alpha-beta t cell Mucosal invariant t cell Unswitched memory b cell Effector memory cd4-positive, alpha-beta t cell T-helper 1 cell T-helper 22 cell Ilc1, human Cd16-negative, cd56-bright natural killer cell, human Monocyte Megakaryocyte Cd14-positive monocyte Myeloid dendritic cell Immature b cell Plasmablast Dendritic cell, human Malignant cell Naive thymus-derived cd8-positive, alpha-beta t cell Central memory cd4-positive, alpha-beta t cell Group 2 innate lymphoid cell, human Effector memory cd8-positive, alpha-beta t cell Hematopoietic precursor cell T-helper 17 cell Erythroid progenitor cell, mammalian B cell Cd8-positive, alpha-beta t cell Dendritic cell Erythrocyte Regulatory t cell Mature nk t cell Plasmacytoid dendritic cell Cd14-low, cd16-positive monocyte Igm plasma cell T follicular helper cell Natural killer cell Gamma-delta t cell Cd16-positive, cd56-dim natural killer cell, human

Blood

80-year-old stage 66-year-old stage 70-year-old stage Fourth decade stage 77-year-old stage 21-year-old stage 50-year-old stage 57-year-old stage 76-year-old stage 62-year-old stage 46-year-old stage 52-year-old stage 60-year-old stage 44-year-old stage 64-year-old stage 25-year-old stage 65-year-old stage 92-year-old stage 40-year-old stage Eighth decade stage 71-year-old stage Ninth decade stage 63-year-old stage 59-year-old stage 54-year-old stage Fifth decade stage 47-year-old stage 31-year-old stage 56-year-old stage 58-year-old stage 68-year-old stage 51-year-old stage 49-year-old stage 73-year-old stage 30-year-old stage Seventh decade stage 26-year-old stage 84-year-old stage 39-year-old stage 69-year-old stage Third decade stage 38-year-old stage 87-year-old stage 55-year-old stage 83-year-old stage Sixth decade stage

Normal Respiratory system disorder Covid-19

Female Male

10x 3' transcription profiling

Cell

Homo sapiens

L2/3-6 intratelencephalic projecting glutamatergic neuron

Middle temporal gyrus Primary somatosensory cortex Anterior cingulate cortex Primary auditory cortex Dorsolateral prefrontal cortex Primary motor cortex Primary visual cortex Angular gyrus

50-year-old stage 60-year-old stage 42-year-old stage 43-year-old stage 29-year-old stage Sixth decade stage

Normal

Female Male

10x 3' v3

Nucleus

Mus musculus

Neuron

Embryo

Theiler stage 23 Theiler stage 24 Theiler stage 21 Theiler stage 25 Theiler stage 17 Theiler stage 16 Theiler stage 26 Theiler stage 18 Theiler stage 20 Theiler stage 19 Theiler stage 27 Theiler stage 15 Theiler stage 22

Normal

Female Male

Sci-rna-seq3

Nucleus

Homo sapiens

Myofibroblast cell Capillary endothelial cell Igg plasma cell Cd8-positive, alpha-beta regulatory t cell Macrophage Effector memory cd4-positive, alpha-beta t cell Mast cell Cd4-positive helper t cell Endothelial cell of vascular tree Naive t cell Cycling macrophage Myeloid dendritic cell Vein endothelial cell Vascular associated smooth muscle cell Conventional dendritic cell Fibroblast Malignant cell Effector memory cd8-positive, alpha-beta t cell Pericyte Endothelial cell Cycling t cell Memory b cell Plasmacytoid dendritic cell Cd4-positive, cd25-positive, ccr4-positive, alpha-beta regulatory t cell Cycling stromal cell T follicular helper cell Natural killer cell Endothelial cell of artery Exhausted t cell

Breast

80-year-old stage 85-year-old stage 82-year-old stage 66-year-old stage 79-year-old stage 70-year-old stage 32-year-old stage 50-year-old stage 57-year-old stage 62-year-old stage Prime adult stage 46-year-old stage 52-year-old stage 60-year-old stage 60-79 year-old stage 80 year-old and over stage 64-year-old stage 45-year-old stage 25-year-old stage 65-year-old stage 67-year-old stage Middle aged stage Eighth decade stage 37-year-old stage 71-year-old stage Adult stage Ninth decade stage 36-year-old stage 63-year-old stage 59-year-old stage 54-year-old stage Fifth decade stage 47-year-old stage 58-year-old stage 61-year-old stage 34-year-old stage 49-year-old stage 42-year-old stage 35-year-old stage 73-year-old stage 30-year-old stage Seventh decade stage 88-year-old stage 84-year-old stage 69-year-old stage 43-year-old stage Late adult stage 29-year-old stage 38-year-old stage 41-year-old stage 55-year-old stage 83-year-old stage Sixth decade stage

Breast cancer Invasive ductal breast carcinoma Breast mucinous carcinoma Her2 positive breast carcinoma Triple-negative breast carcinoma Invasive lobular breast carcinoma Estrogen-receptor positive breast cancer Metaplastic breast carcinoma Invasive tubular breast carcinoma Breast carcinoma Breast apocrine carcinoma

Female Male

10x 5' v2 10x 5' v1 10x 3' v3 10x 5' transcription profiling 10x 3' v2

Cell

Mus musculus

Cerebellar granule cell Endothelial stalk cell Inhibitory interneuron Glutamatergic neuron Oligodendrocyte precursor cell Oligodendrocyte Macrophage Bergmann glial cell Interneuron Microglial cell Fibroblast Ependymal cell Endothelial cell Cerebellar golgi cell Astrocyte of the cerebellum Purkinje cell

Cerebellum

8-week-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Innate lymphoid cell Cd4-positive, alpha-beta memory t cell Naive thymus-derived cd4-positive, alpha-beta t cell Mucosal invariant t cell Effector memory cd4-positive, alpha-beta t cell Effector memory cd4-positive, alpha-beta t cell, terminally differentiated Germinal center t cell Cd8-positive, alpha-beta memory t cell Naive thymus-derived cd8-positive, alpha-beta t cell Central memory cd4-positive, alpha-beta t cell Group 3 innate lymphoid cell Effector memory cd8-positive, alpha-beta t cell Central memory cd8-positive, alpha-beta t cell Cd4-positive, cd25-positive, alpha-beta regulatory t cell Effector memory cd8-positive, alpha-beta t cell, terminally differentiated Gamma-delta t cell Cd16-positive, cd56-dim natural killer cell, human

Blood Mesenteric lymph node Spleen Epithelial lining fluid Lung Jejunum lamina propria Inguinal lymph node Bone marrow Jejunal epithelium Thoracic lymph node

Fourth decade stage 48-year-old stage 64-year-old stage 25-year-old stage 33-year-old stage 67-year-old stage Eighth decade stage 75-year-old stage 27-year-old stage 23-year-old stage Fifth decade stage 20-year-old stage 56-year-old stage 68-year-old stage 73-year-old stage Third decade stage Sixth decade stage

Normal

Female Male

10x 5' v2 10x 3' v3

Cell

Homo sapiens

Classical monocyte Cd4-positive, alpha-beta t cell Non-classical monocyte Progenitor cell Plasmablast Conventional dendritic cell B cell Cd8-positive, alpha-beta t cell Plasmacytoid dendritic cell Natural killer cell Gamma-delta t cell

Blood

82-year-old stage 66-year-old stage 79-year-old stage 77-year-old stage 50-year-old stage 86-year-old stage 76-year-old stage 62-year-old stage 60-year-old stage 80 year-old and over stage 44-year-old stage 48-year-old stage 45-year-old stage 25-year-old stage 74-year-old stage 33-year-old stage 65-year-old stage 67-year-old stage 75-year-old stage 37-year-old stage 71-year-old stage Adult stage 78-year-old stage 63-year-old stage 59-year-old stage 47-year-old stage 31-year-old stage 58-year-old stage 68-year-old stage 61-year-old stage 34-year-old stage 49-year-old stage 42-year-old stage 35-year-old stage 53-year-old stage 73-year-old stage 39-year-old stage 69-year-old stage 43-year-old stage 38-year-old stage 41-year-old stage 55-year-old stage 83-year-old stage

Normal Respiratory system disorder Covid-19

Female Male

10x 5' transcription profiling

Cell

Homo sapiens

Acinar cell Primordial germ cell Peptic cell Mesenchymal stem cell Erythroid progenitor cell Astrocyte Oligodendrocyte Pulmonary alveolar type 2 cell Macrophage Stratified epithelial cell Cord blood hematopoietic stem cell Mesothelial cell Inflammatory cell Stromal cell Ventricular cardiac muscle cell Mast cell Alternatively activated macrophage Basal cell Epithelial cell Erythroid lineage cell Neutrophil Monocyte Cell of skeletal muscle Endocrine cell Epithelial cell of proximal tubule Fibroblast Renal intercalated cell Sertoli cell Endothelial cell Embryonic stem cell Kidney loop of henle epithelial cell B cell Dendritic cell Plasma cell T cell Thyroid follicular cell Enterocyte Smooth muscle cell Neuron Epithelial cell of exocrine pancreas Chondrocyte Professional antigen presenting cell Myeloid cell Goblet cell

Blood Adrenal gland Ileum Rectum Ureter Uterus Thymus Thyroid gland Liver Spleen Chorionic villus Cerebellum Rib Testis Bladder organ Lung Ovary Esophagus Trachea Fallopian tube Kidney Pancreas Jejunum Gallbladder Transverse colon Brain Adipose tissue Uterine cervix Placenta Umbilical cord blood Prostate gland Omentum Pleura Muscle organ Temporal lobe Eye Sigmoid colon Duodenum Spinal cord Intestine Bone marrow Ascending colon Stomach Embryonic stem cell Skin of body Artery Vermiform appendix Heart Vault of skull

66-year-old stage 13th week post-fertilization stage 12th week post-fertilization stage 21-year-old stage 32-year-old stage 57-year-old stage 10th week post-fertilization stage 62-year-old stage 46-year-old stage 52-year-old stage 60-year-old stage 64-year-old stage 45-year-old stage 25-year-old stage Embryonic stage 26th week post-fertilization stage 27-year-old stage 23-year-old stage 11th week post-fertilization stage 36-year-old stage 63-year-old stage 59-year-old stage 47-year-old stage 56-year-old stage 58-year-old stage 61-year-old stage 34-year-old stage 51-year-old stage 49-year-old stage 14th week post-fertilization stage 30-year-old stage Newborn stage (0-28 days) 43-year-old stage 41-year-old stage 55-year-old stage 83-year-old stage

Normal

Female Male

Microwell-seq

Cell

Homo sapiens

Endothelial cell of lymphatic vessel Cd4-positive, alpha-beta t cell Macrophage Monocyte-derived dendritic cell Adipocyte Monocyte Conventional dendritic cell Fibroblast Pericyte Endothelial cell Follicular dendritic cell Cd8-positive, alpha-beta t cell Dendritic cell Regulatory t cell Plasmacytoid dendritic cell T follicular helper cell Smooth muscle cell Natural killer cell

Lymph node

Fourth decade stage Eighth decade stage Ninth decade stage Fifth decade stage Seventh decade stage Third decade stage Tenth decade stage Sixth decade stage

Normal B-cell non-hodgkin lymphoma

Female Male

10x multiome

Nucleus