Homo sapiens

Innate lymphoid cell Cd16-negative, cd56-bright natural killer cell, human Natural killer cell Cd16-positive, cd56-dim natural killer cell, human

Blood

80-year-old stage 85-year-old stage 82-year-old stage 66-year-old stage 79-year-old stage 70-year-old stage 77-year-old stage 50-year-old stage 86-year-old stage 57-year-old stage 76-year-old stage 62-year-old stage 46-year-old stage 52-year-old stage 60-year-old stage 80 year-old and over stage 44-year-old stage 48-year-old stage 64-year-old stage 89-year-old stage 45-year-old stage 74-year-old stage 65-year-old stage 67-year-old stage 40-year-old stage 75-year-old stage 71-year-old stage 78-year-old stage 63-year-old stage 59-year-old stage 54-year-old stage 47-year-old stage 56-year-old stage 58-year-old stage 68-year-old stage 61-year-old stage 51-year-old stage 49-year-old stage 42-year-old stage 53-year-old stage 72-year-old stage 73-year-old stage 88-year-old stage 84-year-old stage 69-year-old stage 43-year-old stage 87-year-old stage 41-year-old stage 81-year-old stage 55-year-old stage 83-year-old stage

Normal Cytomegalovirus infection

Female Male

10x gene expression flex

Cell

Mus musculus

Midbrain dopaminergic neuron Endodermal cell Hemangioblast Paraxial cell Mesodermal cell Anterior visceral endoderm cell Splanchnic mesodermal cell Spinal cord interneuron Primitive red blood cell Cardiac valve cell Neuroplacodal cell Gut endothelial cell Notochordal cell Surface ectodermal cell Premigratory neural crest cell Neurectodermal cell

Embryo

Theiler stage 14

Normal

Slide-seqv2

Mus musculus

Primordial germ cell Intermediate mesodermal cell Epithelial cell of thymus Corneal epithelial cell Kidney connecting tubule epithelial cell Kidney loop of henle ascending limb epithelial cell Ectodermal cell Pituitary gland cell Epithelial cell of thyroid gland Pancreatic acinar cell Auditory epithelial cell Kidney distal convoluted tubule epithelial cell Metanephric mesenchyme stem cell Epithelial cell of parathyroid gland Kidney collecting duct principal cell Endo-epithelial cell Epithelial cell Olfactory epithelial cell Conjunctiva goblet cell Intrahepatic cholangiocyte Epithelial cell of proximal tubule Kidney collecting duct intercalated cell Bladder urothelial cell Ureteric bud cell Podocyte Lens epithelial cell Epithelial cell of amnion Kidney epithelial cell Notochordal cell Keratinocyte Gingival epithelial cell

Embryo

Theiler stage 23 Theiler stage 24 Theiler stage 21 Theiler stage 13 Theiler stage 25 Theiler stage 17 Theiler stage 16 Theiler stage 26 Theiler stage 12 Theiler stage 18 Theiler stage 20 Theiler stage 19 Theiler stage 27 Theiler stage 14 Theiler stage 15 Theiler stage 22

Normal

Female Male

Sci-rna-seq3

Nucleus

Homo sapiens

Radial glial cell

Upper layers of the cortex Dorsal plus ventral thalamus Head Entorhinal cortex Cerebral subcortex Caudate-putamen Hippocampal formation Hypothalamus Diencephalon Forebrain Cerebellum Telencephalon Choroid plexus epithelium Cerebellar peduncular complex Frontal cortex Brain Striatum Pons Midbrain Lower layers of the cortex Medulla oblongata Hindbrain Cortex Midbrain tectum Basal forebrain Occipital cortex Metencephalon

9th week post-fertilization stage 13th week post-fertilization stage 12th week post-fertilization stage 10th week post-fertilization stage Carnegie stage 22 11th week post-fertilization stage 15th week post-fertilization stage 14th week post-fertilization stage Carnegie stage 15 Carnegie stage 20 Carnegie stage 18 Carnegie stage 16

Normal

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Antibody secreting cell Lymphocyte Monocyte Hematopoietic precursor cell Endothelial cell B cell Dendritic cell Hematopoietic multipotent progenitor cell

Blood

80-year-old stage 85-year-old stage 82-year-old stage 66-year-old stage 70-year-old stage 77-year-old stage 32-year-old stage 50-year-old stage 86-year-old stage 57-year-old stage 76-year-old stage 62-year-old stage 46-year-old stage 93-year-old stage 60-year-old stage 44-year-old stage 48-year-old stage 89-year-old stage 25-year-old stage 33-year-old stage 65-year-old stage 67-year-old stage 92-year-old stage 40-year-old stage 75-year-old stage 23-year-old stage 37-year-old stage 71-year-old stage 78-year-old stage 28-year-old stage 36-year-old stage 63-year-old stage 59-year-old stage 54-year-old stage 47-year-old stage 31-year-old stage 58-year-old stage 68-year-old stage 61-year-old stage 34-year-old stage 51-year-old stage 49-year-old stage 72-year-old stage 73-year-old stage 30-year-old stage 26-year-old stage 84-year-old stage 39-year-old stage 90-year-old stage 69-year-old stage 43-year-old stage 38-year-old stage 41-year-old stage 81-year-old stage 55-year-old stage 83-year-old stage

Normal Myelodysplastic/myeloproliferative disease Myelodysplastic syndrome Hematologic disorder

Female Male

10x 3' v3

Cell

Drosophila melanogaster

Eo sensory organ accessory cell Adult heart ventral longitudinal muscle cell Muscle cell Adult alary muscle cell Escort cell Enteroendocrine cell Germline cell Mechanosensory neuron Follicle cell Epithelial cell Sensory neuron Adult somatic muscle cell of head Embryonic/larval crystal cell Adult brain perineurial glial cell Indirect flight muscle cell Hemocyte Ovarian sheath muscle cell Adult renal stem cell Cell body glial cell Subperineurial glial cell Visceral muscle cell

Body proper Ovary Adult oenocyte Antenna Leg Wing Testis Trachea Male reproductive gland Fat body Insect proboscis Haltere Head Gut Malpighian tubule Heart Body wall

Day 1 of adulthood Day 3 of adulthood Day 5 of adulthood Day 2 of adulthood

Normal

Female Male Mixed sex

10x 3' v3

Rattus norvegicus

Cardiac neuron Schwann cell Cardiac atrium fibroblast Cardiac endothelial cell Endothelial cell of lymphatic vessel Mesothelial cell of epicardium Club cell Macrophage Mast cell Brown adipocyte Non-myelinating schwann cell Monocyte White adipocyte Regular atrial cardiac myocyte Vascular associated smooth muscle cell Fibroblast Cardiac ventricle fibroblast Pericyte Endothelial cell Cardiac pacemaker cell of sinoatrial node Peripheral nervous system neuron Regular ventricular cardiac myocyte B cell Cd8-positive, alpha-beta t cell Myocyte of atrioventricular node Cycling t cell Dendritic cell Fibroblast of cardiac tissue T cell Cd14-low, cd16-positive monocyte Myocyte of sinoatrial node Natural killer cell Eukaryotic cell

Normal

10x 3' v2

Homo sapiens

Antibody secreting cell Lymphocyte Monocyte Hematopoietic precursor cell Endothelial cell B cell Dendritic cell Hematopoietic multipotent progenitor cell

Blood

80-year-old stage 85-year-old stage 91-year-old stage 82-year-old stage 66-year-old stage 79-year-old stage 70-year-old stage 77-year-old stage 32-year-old stage 50-year-old stage 76-year-old stage 62-year-old stage 46-year-old stage 52-year-old stage 60-year-old stage 48-year-old stage 64-year-old stage 89-year-old stage 45-year-old stage 74-year-old stage 65-year-old stage 67-year-old stage 40-year-old stage 75-year-old stage 27-year-old stage 37-year-old stage 71-year-old stage 78-year-old stage 63-year-old stage 59-year-old stage 54-year-old stage 47-year-old stage 31-year-old stage 56-year-old stage 58-year-old stage 68-year-old stage 61-year-old stage 34-year-old stage 51-year-old stage 53-year-old stage 94-year-old stage 72-year-old stage 73-year-old stage 26-year-old stage 88-year-old stage 84-year-old stage 39-year-old stage 90-year-old stage 69-year-old stage 43-year-old stage 41-year-old stage 81-year-old stage 55-year-old stage 83-year-old stage

Normal Myelodysplastic/myeloproliferative disease Myelodysplastic syndrome Hematologic disorder

Female Male

10x 3' v3

Cell

Homo sapiens

Oligodendrocyte

Inferior frontal gyrus Middle temporal gyrus Putamen Brodmann (1909) area 24 Cerebellar vermis Posterior parahippocampal gyrus Anterior olfactory nucleus Brodmann (1909) area 38 Pretectal region Subicular complex Gray matter of midbrain Brodmann (1909) area 14 Brodmann (1909) area 19 Inferior temporal gyrus Hypothalamus Brodmann (1909) area 32 Cerebrocerebellum Dentate gyrus of hippocampal formation Lateral geniculate body Bed nucleus of stria terminalis Median tuberal portion Brodmann (1909) area 13 Primary somatosensory cortex Medial geniculate body Preoptic area Substantia innominata Perirhinal cortex Body of caudate nucleus Extrastriate cortex Lateral nuclear group of thalamus Dorsal tegmental nucleus Brodmann (1909) area 23 Centromedian nucleus of thalamus Brodmann (1909) area 35 Epithalamus Substantia nigra Central amygdaloid nucleus Rostral ca3 Granular insular cortex Agranular insular cortex Globus pallidus Basolateral amygdaloid nuclear complex Parabrachial nucleus Ventral anterior nucleus of thalamus Nucleus of dorsal thalamus Anterior cortical amygdaloid nucleus Anterior nuclear group Brodmann (1909) area 43 Primary auditory cortex Medial entorhinal cortex Red nucleus Corticomedial nuclear complex Lateral posterior nucleus of thalamus Brodmann (1909) area 46 Nucleus of medulla oblongata Supraoptic nucleus Uncal ca1 Cerebellar nuclear complex Temporal fusiform gyrus Lateral entorhinal cortex Brodmann (1909) area 25 Midbrain nucleus Primary motor cortex Pulvinar nucleus Pontine tegmentum Primary visual cortex Subthalamic nucleus Spinal cord Superior parietal cortex Hippocampal field Inferior olivary complex Piriform cortex Lateral amygdaloid nucleus Brodmann (1909) area 40 Claustrum of brain Midbrain tectum Mammillary body Pontine reticular formation Pontine nuclear group Medial dorsal nucleus of thalamus Retrosplenial region Nucleus accumbens Medial zone of hypothalamus Intralaminar nuclear group Accessory basal amygdaloid nucleus Superior temporal gyrus Septal nuclear complex Cuneus cortex

50-year-old stage 60-year-old stage 42-year-old stage 29-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Capillary endothelial cell Activated cd8-positive, alpha-beta t cell Endothelial cell of lymphatic vessel Macrophage Mesothelial cell Cd14-positive, cd16-positive monocyte Mast cell Epicardial adipocyte Monocyte Cd14-positive monocyte Cd8-positive, alpha-beta cytotoxic t cell Vein endothelial cell Regular atrial cardiac myocyte Fibroblast Pericyte Endothelial cell Regular ventricular cardiac myocyte B cell Cd4-positive, alpha-beta cytotoxic t cell Activated cd4-positive, alpha-beta t cell Dendritic cell Mature nk t cell Smooth muscle cell Natural killer cell Endothelial cell of artery Neural cell

Interventricular septum Apex of heart Heart left ventricle Left cardiac atrium Right cardiac atrium Heart right ventricle

Eighth decade stage Fifth decade stage Seventh decade stage Sixth decade stage

Normal

Female Male

10x 3' v3 10x 3' v2

Nucleus Cell

Homo sapiens

Pro-b cell Common myeloid progenitor Promonocyte Schwann cell Capillary endothelial cell Naive b cell Ciliated epithelial cell Endothelial cell of lymphatic vessel Cd4-positive, alpha-beta t cell Double-positive, alpha-beta thymocyte Cd8-positive, alpha-beta regulatory t cell Large pre-b-ii cell Macrophage Mesothelial cell Granulocyte monocyte progenitor cell Neuro-medullary thymic epithelial cell Late pro-b cell Mast cell Small pre-b-ii cell Medullary thymic epithelial cell type 2 Thymic fibroblast type 2 Neutrophil Immature alpha-beta t cell Monocyte Myo-medullary thymic epithelial cell Double negative thymocyte Vein endothelial cell Cd8-positive, alpha-beta memory t cell Conventional dendritic cell Fibroblast Medullary thymic epithelial cell type 1 Pericyte B cell Cd8-positive, alpha-beta t cell Early t lineage precursor Cortical thymic epithelial cell Corticomedullary thymic epithelial cell Plasma cell Erythrocyte Regulatory t cell T cell Memory b cell Plasmacytoid dendritic cell Myelocyte Precursor b cell Thymic fibroblast type 1 Smooth muscle cell Natural killer cell Endothelial cell of artery Gamma-delta t cell Medullary thymic epithelial cell type 3

Thymus

6-month-old stage 3-month-old stage 13th week post-fertilization stage 12th week post-fertilization stage 14-month-old stage 5-month-old stage 2-year-old stage 10-month-old stage 20th week post-fertilization stage 17th week post-fertilization stage 2-month-old stage 15th week post-fertilization stage 14th week post-fertilization stage 24th week post-fertilization stage 18th week post-fertilization stage Newborn stage (0-28 days)

Normal

Female Male

10x 5' v2 10x 5' v1 10x 3' v3 10x 3' v2

Cell

Callithrix jacchus

Glutamatergic neuron

Secondary visual cortex Primary somatosensory cortex Brodmann (1909) area 23 Temporal cortex Primary auditory cortex Dorsolateral prefrontal cortex Temporal lobe Brodmann (1909) area 25 Parietal cortex Primary motor cortex Primary visual cortex Prefrontal cortex

Prime adult stage Late adult stage

Normal

Female Male

10x 3' v3

Nucleus