Homo sapiens

Cell Mast cell Epithelial cell Fibroblast Pericyte Endothelial cell B cell T cell Myeloid cell

Prostate cancer Clear cell renal carcinoma Normal Urinary bladder cancer Lung cancer Pancreatic ductal adenocarcinoma Colorectal carcinoma Breast carcinoma Liver cancer Ovarian cancer

Smart-seq2 10x 3' v3 10x 5' transcription profiling Visium spatial gene expression 10x 3' v2 10x technology

Callithrix jacchus

Mural cell Astrocyte Oligodendrocyte precursor cell Oligodendrocyte Microglial cell Fibroblast Ependymal cell Brain microvascular endothelial cell Neuron Choroid plexus epithelial cell

Normal

10x 3' transcription profiling

Homo sapiens

Cardiac neuron Mural cell Cardiac muscle cell Lymphocyte Mast cell Adipocyte Endothelial cell Fibroblast of cardiac tissue Myeloid cell

Interventricular septum Apex of heart Heart left ventricle Heart right ventricle

Fourth decade stage Postnatal stage Eighth decade stage Fifth decade stage Pediatric stage Seventh decade stage Third decade stage Sixth decade stage

Normal Dilated cardiomyopathy Non-compaction cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy

Female Male

10x 3' v3 10x 3' v2

Nucleus

Homo sapiens

Cd4-positive, alpha-beta memory t cell Cd8-positive, alpha-beta regulatory t cell Naive regulatory t cell Effector memory cd4-positive, alpha-beta t cell Central memory cd4-positive, alpha-beta t cell T cell Memory regulatory t cell Memory ccr4-positive regulatory t cell

Blood

80-year-old stage 85-year-old stage 82-year-old stage 66-year-old stage 79-year-old stage 70-year-old stage 77-year-old stage 50-year-old stage 86-year-old stage 57-year-old stage 76-year-old stage 62-year-old stage 46-year-old stage 52-year-old stage 60-year-old stage 80 year-old and over stage 44-year-old stage 48-year-old stage 64-year-old stage 89-year-old stage 45-year-old stage 74-year-old stage 65-year-old stage 67-year-old stage 40-year-old stage 75-year-old stage 71-year-old stage 78-year-old stage 63-year-old stage 59-year-old stage 54-year-old stage 47-year-old stage 56-year-old stage 58-year-old stage 68-year-old stage 61-year-old stage 51-year-old stage 49-year-old stage 42-year-old stage 53-year-old stage 72-year-old stage 73-year-old stage 88-year-old stage 84-year-old stage 69-year-old stage 43-year-old stage 87-year-old stage 41-year-old stage 81-year-old stage 55-year-old stage 83-year-old stage

Normal Cytomegalovirus infection

Female Male

10x gene expression flex

Cell

Homo sapiens

Classical monocyte Platelet Endothelial cell of arteriole Macrophage Myelinating schwann cell Mast cell Endothelial cell of venule Non-myelinating schwann cell Monocyte Blood vessel smooth muscle cell Fibroblast Pericyte B cell Dendritic cell Plasma cell T cell Fenestrated endothelial cell Retinal pigment epithelial cell Natural killer cell Endothelial cell of artery Melanocyte

Chorioretinal region

82-year-old stage 16-year-old stage 77-year-old stage 13th week post-fertilization stage 12th week post-fertilization stage 21-year-old stage 32-year-old stage 50-year-old stage 86-year-old stage 62-year-old stage 46-year-old stage 60-year-old stage 80 year-old and over stage 64-year-old stage 25-year-old stage 65-year-old stage 27-year-old stage 71-year-old stage 11th week post-fertilization stage 21st week post-fertilization stage 63-year-old stage 17th week post-fertilization stage 47-year-old stage 15th week post-fertilization stage 58-year-old stage 68-year-old stage 34-year-old stage 53-year-old stage 14th week post-fertilization stage 10-year-old stage 17-year-old stage 72-year-old stage 24th week post-fertilization stage 30-year-old stage 18th week post-fertilization stage Newborn stage (0-28 days) 69-year-old stage 43-year-old stage 81-year-old stage 11-year-old stage

Normal

Female Male

10x 5' v2 10x 3' v3

Nucleus

Homo sapiens

Classical monocyte Cd4-positive, alpha-beta t cell Double-positive, alpha-beta thymocyte Non-classical monocyte Double negative t regulatory cell Mucosal invariant t cell Mast cell Blood cell Megakaryocyte-erythroid progenitor cell Plasmablast Hematopoietic stem cell Enucleated reticulocyte B cell Cd8-positive, alpha-beta t cell Dendritic cell Natural killer cell Gamma-delta t cell

Blood

Young adult stage Fourth decade stage Eighth decade stage Ninth decade stage Fifth decade stage Seventh decade stage 90 year-old and over stage Sixth decade stage

Normal Influenza Covid-19

Female Male

10x 5' v1

Cell

Homo sapiens

Schwann cell Endothelial cell of lymphatic vessel Leukocyte Lymphocyte Macrophage Myelinating schwann cell Mast cell Epithelial cell Monocyte Keratocyte Progenitor cell Fibroblast Blood vessel endothelial cell Pericyte Endothelial cell Corneal endothelial cell B cell Conjunctival epithelial cell Smooth muscle cell Melanocyte

Corneal epithelium Corneal endothelium Sclera Tunica fibrosa of eyeball Cornea Corneo-scleral junction Substantia propria of cornea Ocular surface region

16-year-old stage 70-year-old stage 77-year-old stage 13th week post-fertilization stage 32-year-old stage 86-year-old stage 62-year-old stage 22-year-old stage 23rd week post-fertilization stage 48-year-old stage 64-year-old stage 45-year-old stage 25-year-old stage 74-year-old stage 33-year-old stage 65-year-old stage 67-year-old stage 1-year-old stage 2-year-old stage Postnatal stage Eighth decade stage 75-year-old stage 27-year-old stage 11th week post-fertilization stage 21st week post-fertilization stage 19th week post-fertilization stage 20th week post-fertilization stage 17th week post-fertilization stage 15th week post-fertilization stage 22nd week post-fertilization stage 61-year-old stage 34-year-old stage 51-year-old stage 53-year-old stage 14th week post-fertilization stage 10-year-old stage 72-year-old stage 13-year-old stage 18th week post-fertilization stage 84-year-old stage 39-year-old stage Newborn stage (0-28 days) 69-year-old stage 43-year-old stage 90 year-old and over stage 87-year-old stage 41-year-old stage 55-year-old stage 83-year-old stage 11-year-old stage

Normal

Female Male

10x 3' v3 10x multiome 10x 3' v2

Cell Nucleus

Mus musculus

Common myeloid progenitor Naive b cell Follicular b cell Natural t-regulatory cell Cytotoxic t cell Leukocyte Macrophage Mucosal invariant t cell Transitional stage b cell Marginal zone b cell of lymph node Naive t cell Neutrophil Cd103-positive dendritic cell Plasmablast Conventional dendritic cell Group 3 innate lymphoid cell T-helper 17 cell Cycling t cell Group 2 innate lymphoid cell Plasma cell Lymphoid tissue–inducer cell Mature nk t cell T cell Bm3 b cell Plasmacytoid dendritic cell Centrocyte Basophil Eosinophil Germinal center b cell

Normal

10x 3' v3

Homo sapiens

Kupffer cell Acinar cell Best4+ enterocyte Luminal cell of prostate epithelium Schwann cell Pancreatic ductal cell Pulmonary alveolar type 1 cell Hepatoblast Colon epithelial cell Pulmonary alveolar type 2 cell Club cell Mesothelial cell Stromal cell Interstitial cell of cajal Basal cell Mesodermal cell Epithelial cell Type b pancreatic cell Paneth cell Epithelial cell of pancreas Pancreatic epsilon cell Pancreatic d cell Stem cell Enteroendocrine cell Hematopoietic cell Intestinal tuft cell Pericyte Endothelial cell Pancreatic a cell Thymocyte Hepatic stellate cell Epithelial cell of stomach Neuroendocrine cell Enterocyte Smooth muscle cell Neuron Lung secretory cell Ciliated cell M cell of gut Goblet cell

Ileum Thyroid gland Liver Common bile duct Lung Bronchus Alveolar sac Pancreas Gallbladder Prostate gland Biliary system Pyloric antrum Corpus Lung epithelium Duodenum Salivary gland epithelium Colon Nasopharynx Intrahepatic bile duct Intestine Stomach

Normal

Cel-seq2 10x 5' v1 10x 3' v3 Sort-seq Seq-well s3 10x multiome 10x 3' v2 Smart-seq

Cell Nucleus

Homo sapiens

Luminal hormone-sensing cell of mammary gland Mural cell Endothelial cell of lymphatic vessel Leukocyte Luminal adaptive secretory precursor cell of mammary gland Perivascular cell Luminal epithelial cell of mammary gland Fibroblast of mammary gland Blood vessel endothelial cell Basal-myoepithelial cell of mammary gland Mammary gland epithelial cell

Breast

19-year-old stage 21-year-old stage 57-year-old stage 62-year-old stage 46-year-old stage 52-year-old stage 48-year-old stage 45-year-old stage 25-year-old stage 33-year-old stage 65-year-old stage 40-year-old stage 27-year-old stage 23-year-old stage 37-year-old stage 28-year-old stage 36-year-old stage 63-year-old stage 59-year-old stage 20-year-old stage 31-year-old stage 56-year-old stage 58-year-old stage 34-year-old stage 35-year-old stage 53-year-old stage 30-year-old stage 24-year-old stage 39-year-old stage 29-year-old stage 38-year-old stage 41-year-old stage 55-year-old stage

Normal

Female

10x 3' v3

Cell

Homo sapiens

Naive thymus-derived cd4-positive, alpha-beta t cell

Blood

80-year-old stage 85-year-old stage 82-year-old stage 66-year-old stage 79-year-old stage 70-year-old stage 77-year-old stage 50-year-old stage 86-year-old stage 57-year-old stage 76-year-old stage 62-year-old stage 46-year-old stage 52-year-old stage 60-year-old stage 80 year-old and over stage 44-year-old stage 48-year-old stage 64-year-old stage 89-year-old stage 45-year-old stage 74-year-old stage 65-year-old stage 67-year-old stage 40-year-old stage 75-year-old stage 71-year-old stage 78-year-old stage 63-year-old stage 59-year-old stage 54-year-old stage 47-year-old stage 56-year-old stage 58-year-old stage 68-year-old stage 61-year-old stage 51-year-old stage 49-year-old stage 42-year-old stage 53-year-old stage 72-year-old stage 73-year-old stage 88-year-old stage 84-year-old stage 69-year-old stage 43-year-old stage 87-year-old stage 41-year-old stage 81-year-old stage 55-year-old stage 83-year-old stage

Normal Cytomegalovirus infection

Female Male

10x gene expression flex

Cell

Mus musculus Homo sapiens

Cerebellar granule cell Endothelial stalk cell Inhibitory interneuron Cerebellar neuron Oligodendrocyte precursor cell Oligodendrocyte Macrophage Bergmann glial cell Obsolete excitatory neuron Interneuron Microglial cell Fibroblast Ependymal cell Endothelial cell Cerebellar golgi cell Astrocyte of the cerebellum Purkinje cell

Normal

10x 3' v3