Homo sapiens

T cell Cell Endothelial cell Mast cell Epithelial cell Myeloid cell B cell Pericyte Fibroblast

Ovarian cancer Prostate cancer Clear cell renal carcinoma Liver cancer Colorectal carcinoma Pancreatic ductal adenocarcinoma Normal Breast carcinoma Lung cancer Urinary bladder cancer

10x technology 10x 5' transcription profiling Visium spatial gene expression Smart-seq2 10x 3' v3 10x 3' v2

Callithrix jacchus

Oligodendrocyte precursor cell Oligodendrocyte Ependymal cell Microglial cell Brain microvascular endothelial cell Mural cell Choroid plexus epithelial cell Neuron Astrocyte Fibroblast

Normal

10x 3' transcription profiling

Homo sapiens

Endothelial cell Mast cell Cardiac neuron Lymphocyte Adipocyte Mural cell Myeloid cell Cardiac muscle cell Fibroblast of cardiac tissue

Heart right ventricle Apex of heart Heart left ventricle Interventricular septum

Pediatric stage Sixth decade stage Fifth decade stage Third decade stage Seventh decade stage Postnatal stage Fourth decade stage Eighth decade stage

Arrhythmogenic right ventricular cardiomyopathy Dilated cardiomyopathy Normal Non-compaction cardiomyopathy

Female Male

10x 3' v3 10x 3' v2

Nucleus

Homo sapiens

Central memory cd4-positive, alpha-beta t cell T cell Effector memory cd4-positive, alpha-beta t cell Memory regulatory t cell Naive regulatory t cell Memory ccr4-positive regulatory t cell Cd4-positive, alpha-beta memory t cell Cd8-positive, alpha-beta regulatory t cell

Blood

66-year-old stage 69-year-old stage 75-year-old stage 65-year-old stage 42-year-old stage 89-year-old stage 43-year-old stage 87-year-old stage 71-year-old stage 85-year-old stage 53-year-old stage 61-year-old stage 88-year-old stage 52-year-old stage 54-year-old stage 68-year-old stage 48-year-old stage 44-year-old stage 56-year-old stage 55-year-old stage 84-year-old stage 82-year-old stage 50-year-old stage 80-year-old stage 51-year-old stage 57-year-old stage 72-year-old stage 81-year-old stage 74-year-old stage 80 year-old and over stage 49-year-old stage 58-year-old stage 59-year-old stage 67-year-old stage 77-year-old stage 64-year-old stage 45-year-old stage 62-year-old stage 86-year-old stage 41-year-old stage 70-year-old stage 46-year-old stage 60-year-old stage 78-year-old stage 63-year-old stage 47-year-old stage 76-year-old stage 79-year-old stage 73-year-old stage 83-year-old stage 40-year-old stage

Cytomegalovirus infection Normal

Female Male

10x gene expression flex

Cell

Homo sapiens

T cell Endothelial cell of venule Natural killer cell Non-myelinating schwann cell Retinal pigment epithelial cell Mast cell Platelet Endothelial cell of arteriole Blood vessel smooth muscle cell Endothelial cell of artery Melanocyte Classical monocyte Macrophage Fenestrated endothelial cell Plasma cell B cell Pericyte Monocyte Fibroblast Myelinating schwann cell Dendritic cell

Chorioretinal region

69-year-old stage 21-year-old stage 21st week post-fertilization stage 34-year-old stage 65-year-old stage 43-year-old stage 13th week post-fertilization stage 71-year-old stage 53-year-old stage 68-year-old stage 30-year-old stage 14th week post-fertilization stage 17-year-old stage 15th week post-fertilization stage 82-year-old stage 50-year-old stage 17th week post-fertilization stage 72-year-old stage 12th week post-fertilization stage 81-year-old stage 80 year-old and over stage 16-year-old stage 58-year-old stage 25-year-old stage 18th week post-fertilization stage 32-year-old stage 77-year-old stage 64-year-old stage 62-year-old stage 86-year-old stage 46-year-old stage 60-year-old stage Newborn stage (0-28 days) 63-year-old stage 47-year-old stage 11-year-old stage 27-year-old stage 24th week post-fertilization stage 10-year-old stage 11th week post-fertilization stage

Normal

Female Male

10x 5' v2 10x 3' v3

Nucleus

Homo sapiens

Natural killer cell Double negative t regulatory cell Gamma-delta t cell Enucleated reticulocyte Mast cell Cd8-positive, alpha-beta t cell Double-positive, alpha-beta thymocyte Classical monocyte Plasmablast Hematopoietic stem cell Cd4-positive, alpha-beta t cell B cell Mucosal invariant t cell Megakaryocyte-erythroid progenitor cell Blood cell Dendritic cell Non-classical monocyte

Blood

Sixth decade stage Fifth decade stage Seventh decade stage 90 year-old and over stage Fourth decade stage Eighth decade stage Ninth decade stage Young adult stage

Covid-19 Normal Influenza

Female Male

10x 5' v1

Cell

Homo sapiens

Blood vessel endothelial cell Endothelial cell of lymphatic vessel Conjunctival epithelial cell Endothelial cell Mast cell Schwann cell Melanocyte Leukocyte Smooth muscle cell Epithelial cell Lymphocyte Macrophage B cell Pericyte Progenitor cell Monocyte Fibroblast Myelinating schwann cell Keratocyte Corneal endothelial cell

Corneal epithelium Cornea Tunica fibrosa of eyeball Sclera Substantia propria of cornea Ocular surface region Corneal endothelium Corneo-scleral junction

69-year-old stage 75-year-old stage 19th week post-fertilization stage 13-year-old stage 21st week post-fertilization stage 34-year-old stage 65-year-old stage 23rd week post-fertilization stage 43-year-old stage 87-year-old stage 13th week post-fertilization stage 53-year-old stage 61-year-old stage 2-year-old stage 48-year-old stage 14th week post-fertilization stage 39-year-old stage 55-year-old stage 84-year-old stage 15th week post-fertilization stage 20th week post-fertilization stage 51-year-old stage 17th week post-fertilization stage 72-year-old stage 74-year-old stage 16-year-old stage 25-year-old stage 67-year-old stage 18th week post-fertilization stage 90 year-old and over stage 32-year-old stage 77-year-old stage 33-year-old stage 64-year-old stage Postnatal stage 22nd week post-fertilization stage 45-year-old stage 62-year-old stage 86-year-old stage 41-year-old stage 70-year-old stage 1-year-old stage 22-year-old stage Newborn stage (0-28 days) Eighth decade stage 83-year-old stage 11-year-old stage 27-year-old stage 10-year-old stage 11th week post-fertilization stage

Normal

Female Male

10x multiome 10x 3' v3 10x 3' v2

Cell Nucleus

Mus musculus

T cell Neutrophil Germinal center b cell Cycling t cell Cytotoxic t cell Mature nk t cell Centrocyte Group 2 innate lymphoid cell Natural t-regulatory cell Leukocyte Plasmacytoid dendritic cell Group 3 innate lymphoid cell Marginal zone b cell of lymph node T-helper 17 cell Macrophage Follicular b cell Cd103-positive dendritic cell Plasmablast Common myeloid progenitor Plasma cell Eosinophil Bm3 b cell Naive t cell Mucosal invariant t cell Lymphoid tissue–inducer cell Transitional stage b cell Naive b cell Basophil Conventional dendritic cell

Normal

10x 3' v3

Homo sapiens

Club cell Epithelial cell of stomach Stromal cell Ciliated cell Luminal cell of prostate epithelium Lung secretory cell Best4+ enterocyte Endothelial cell Kupffer cell Neuroendocrine cell Interstitial cell of cajal Epithelial cell of pancreas Hepatoblast Stem cell Basal cell Schwann cell Smooth muscle cell Paneth cell Epithelial cell Intestinal tuft cell Hepatic stellate cell Pancreatic a cell Enteroendocrine cell Mesodermal cell Goblet cell Thymocyte Pancreatic d cell Pulmonary alveolar type 1 cell Enterocyte Type b pancreatic cell Acinar cell Mesothelial cell Pancreatic epsilon cell Pericyte Neuron Colon epithelial cell Pancreatic ductal cell Hematopoietic cell Pulmonary alveolar type 2 cell M cell of gut

Bronchus Lung Stomach Corpus Biliary system Duodenum Pyloric antrum Intrahepatic bile duct Nasopharynx Ileum Liver Thyroid gland Colon Alveolar sac Intestine Pancreas Common bile duct Lung epithelium Gallbladder Prostate gland Salivary gland epithelium

Normal

Smart-seq 10x multiome Sort-seq 10x 5' v1 10x 3' v3 Cel-seq2 10x 3' v2 Seq-well s3

Cell Nucleus

Homo sapiens

Blood vessel endothelial cell Endothelial cell of lymphatic vessel Fibroblast of mammary gland Perivascular cell Mammary gland epithelial cell Luminal epithelial cell of mammary gland Leukocyte Luminal adaptive secretory precursor cell of mammary gland Mural cell Basal-myoepithelial cell of mammary gland Luminal hormone-sensing cell of mammary gland

Breast

37-year-old stage 21-year-old stage 34-year-old stage 65-year-old stage 53-year-old stage 52-year-old stage 48-year-old stage 30-year-old stage 39-year-old stage 29-year-old stage 38-year-old stage 56-year-old stage 55-year-old stage 28-year-old stage 57-year-old stage 24-year-old stage 23-year-old stage 35-year-old stage 58-year-old stage 59-year-old stage 25-year-old stage 33-year-old stage 45-year-old stage 62-year-old stage 41-year-old stage 46-year-old stage 31-year-old stage 36-year-old stage 19-year-old stage 63-year-old stage 20-year-old stage 27-year-old stage 40-year-old stage

Normal

Female

10x 3' v3

Cell

Homo sapiens

Naive thymus-derived cd4-positive, alpha-beta t cell

Blood

66-year-old stage 69-year-old stage 75-year-old stage 65-year-old stage 42-year-old stage 89-year-old stage 43-year-old stage 87-year-old stage 71-year-old stage 85-year-old stage 53-year-old stage 61-year-old stage 88-year-old stage 52-year-old stage 54-year-old stage 68-year-old stage 48-year-old stage 44-year-old stage 56-year-old stage 55-year-old stage 84-year-old stage 82-year-old stage 50-year-old stage 80-year-old stage 51-year-old stage 57-year-old stage 72-year-old stage 81-year-old stage 74-year-old stage 80 year-old and over stage 49-year-old stage 58-year-old stage 59-year-old stage 67-year-old stage 77-year-old stage 64-year-old stage 45-year-old stage 62-year-old stage 86-year-old stage 41-year-old stage 70-year-old stage 46-year-old stage 60-year-old stage 78-year-old stage 63-year-old stage 47-year-old stage 76-year-old stage 79-year-old stage 73-year-old stage 83-year-old stage 40-year-old stage

Cytomegalovirus infection Normal

Female Male

10x gene expression flex

Cell

Mus musculus Homo sapiens

Cerebellar neuron Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Astrocyte of the cerebellum Cerebellar granule cell Cerebellar golgi cell Inhibitory interneuron Ependymal cell Macrophage Microglial cell Obsolete excitatory neuron Endothelial stalk cell Interneuron Bergmann glial cell Purkinje cell Fibroblast

Normal

10x 3' v3