Homo sapiens

Myoepithelial cell Schwann cell Mural cell Endothelial cell of lymphatic vessel Macrophage Mast cell Cd4-positive helper t cell Neutrophil Acinar cell of salivary gland Fibroblast Blood vessel endothelial cell Salivary gland glandular cell Cd8-positive, alpha-beta t cell Dendritic cell Plasma cell Keratinocyte Natural killer cell Melanocyte Langerhans cell

Mucosa of lip Buccal mucosa

22-year-old stage 33-year-old stage 65-year-old stage 28-year-old stage 56-year-old stage 61-year-old stage 24-year-old stage 39-year-old stage

Normal

Female Male

10x 3' v3

Cell

Mus musculus

Kidney loop of henle thick ascending limb epithelial cell Kidney granular cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney interstitial fibroblast Kidney collecting duct principal cell Macula densa epithelial cell Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Podocyte Endothelial cell Mesangial cell Kidney proximal convoluted tubule epithelial cell

Kidney

6-month-old stage

Autosomal dominant polycystic kidney disease

Male

Slide-seqv2

Mus musculus

Cd8-positive, alpha-beta thymocyte Double-positive, alpha-beta thymocyte Leukocyte Mature cd4 single-positive thymocyte Cd4-positive, alpha-beta thymocyte Mature cd8 single-positive thymocyte

Thymus

7-week-old stage 10-week-old stage 24-day-old stage 4-week-old stage 5-week-old stage 6-week-old stage

Normal

Female

10x 3' v3

Cell

Homo sapiens

Corticothalamic-projecting glutamatergic cortical neuron

Dorsolateral prefrontal cortex

80-year-old stage 85-year-old stage 82-year-old stage 70-year-old stage 77-year-old stage 50-year-old stage 86-year-old stage 80 year-old and over stage 89-year-old stage 75-year-old stage 78-year-old stage 68-year-old stage 42-year-old stage 72-year-old stage 88-year-old stage 84-year-old stage 69-year-old stage 29-year-old stage 87-year-old stage 81-year-old stage 83-year-old stage

Normal Dementia

Female Male

10x 3' v3 10x multiome

Nucleus

Drosophila melanogaster

Primary pigment cell Compound eye cone cell Eye photoreceptor cell Photoreceptor cell r7 Interommatidial cell Photoreceptor cell r8

Compound eye

Fully formed stage

Normal

Female Male

10x genomics v3

Homo sapiens

Adipocyte of omentum tissue Mesenchymal stem cell of adipose tissue

Visceral fat

48-year-old stage 33-year-old stage Adult stage 28-year-old stage 34-year-old stage 53-year-old stage 24-year-old stage 29-year-old stage 41-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Oligodendrocyte precursor cell

Dorsolateral prefrontal cortex

80-year-old stage 85-year-old stage 82-year-old stage 70-year-old stage 77-year-old stage 50-year-old stage 86-year-old stage 80 year-old and over stage 89-year-old stage 75-year-old stage 78-year-old stage 68-year-old stage 42-year-old stage 72-year-old stage 88-year-old stage 84-year-old stage 69-year-old stage 29-year-old stage 87-year-old stage 81-year-old stage 83-year-old stage

Normal Dementia

Female Male

10x 3' v3 10x multiome

Nucleus

Mus musculus

Kidney loop of henle thick ascending limb epithelial cell Kidney granular cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney interstitial fibroblast Kidney collecting duct principal cell Macula densa epithelial cell Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Podocyte Endothelial cell Mesangial cell Kidney proximal convoluted tubule epithelial cell

Kidney

13-week-old stage

Normal

Male

Slide-seqv2

Homo sapiens

Astrocyte Oligodendrocyte precursor cell Oligodendrocyte Leukocyte Fibroblast Ependymal cell Pericyte Endothelial cell Neuron Central nervous system macrophage

Lateral amygdaloid nucleus

50-year-old stage 42-year-old stage 29-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Sst gabaergic interneuron

Neocortex

Adult stage

Normal

Female Male

10x 3' v3

Cell

Mus musculus

Schwann cell Mesenchymal stem cell Macrophage Cell of skeletal muscle Endothelial cell Skeletal muscle satellite cell B cell T cell Smooth muscle cell

Limb muscle

3-month-old stage 20-month-old stage and over 18-month-old stage 4-week-old stage

Normal

Female Male

10x 3' v2

Cell

Homo sapiens

Luminal cell of prostate epithelium Prostate stromal cell Leukocyte Basal cell of prostate epithelium Epithelial cell of urethra Smooth muscle cell of prostate Prostate gland microvascular endothelial cell Secretory cell Neuroendocrine cell

Transition zone of prostate Peripheral zone of prostate

57-year-old stage 74-year-old stage 31-year-old stage 72-year-old stage 29-year-old stage

Normal Benign prostatic hyperplasia

Male

10x 3' v2

Cell