Mus musculus

Kidney loop of henle thick ascending limb epithelial cell Kidney granular cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney interstitial fibroblast Kidney collecting duct principal cell Macula densa epithelial cell Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Podocyte Endothelial cell Mesangial cell Kidney proximal convoluted tubule epithelial cell

Kidney

13-week-old stage

Normal

Male

Slide-seqv2

Homo sapiens

Inflammatory macrophage Classical monocyte Non-classical monocyte Macrophage Mast cell Alternatively activated macrophage Neutrophil Myeloid dendritic cell Conventional dendritic cell Plasmacytoid dendritic cell Myeloid cell

Breast

Prime adult stage Adult stage

Normal

Female

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Mesothelial cell

Omental fat pad

36-year-old stage 68-year-old stage 35-year-old stage 53-year-old stage 73-year-old stage 24-year-old stage 29-year-old stage 41-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Mus musculus

Astrocyte Oligodendrocyte Obsolete excitatory neuron Brain microvascular endothelial cell

Normal

10x 3' v2

Mus musculus

Kidney loop of henle thick ascending limb epithelial cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney interstitial fibroblast Kidney collecting duct principal cell Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Endothelial cell Kidney proximal convoluted tubule epithelial cell

Kidney

6-month-old stage

Normal

Male

Slide-seqv2

Mus musculus

Kidney loop of henle thick ascending limb epithelial cell Kidney granular cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney interstitial fibroblast Kidney collecting duct principal cell Macula densa epithelial cell Blood vessel smooth muscle cell Podocyte Endothelial cell Mesangial cell Kidney proximal convoluted tubule epithelial cell

Kidney

13-week-old stage

Normal

Male

Slide-seqv2

Homo sapiens

Astrocyte Oligodendrocyte precursor cell Oligodendrocyte Leukocyte Vascular associated smooth muscle cell Fibroblast Ependymal cell Pericyte Endothelial cell Neuron Central nervous system macrophage

Nucleus accumbens

50-year-old stage 42-year-old stage 29-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Myofibroblast cell Best4+ enterocyte Paneth cell of colon Enterochromaffin-like cell Innate lymphoid cell Cd4-positive, alpha-beta t cell Naive thymus-derived cd4-positive, alpha-beta t cell Enterocyte of epithelium of large intestine Mast cell Neutrophil Monocyte Myeloid dendritic cell Type l enteroendocrine cell Tuft cell of colon Colon macrophage Fibroblast Transit amplifying cell of colon Myeloid leukocyte B cell Cd8-positive, alpha-beta t cell Enteroglial cell Plasma cell Regulatory t cell Mature nk t cell Colon endothelial cell Intestinal crypt stem cell of colon Large intestine goblet cell Natural killer cell Gamma-delta t cell

Sigmoid colon Ascending colon Large intestine

60-year-old stage 37-year-old stage 59-year-old stage 56-year-old stage 61-year-old stage

Normal

Female Male

Smart-seq2 10x 3' v3

Cell

Homo sapiens

L2/3-6 intratelencephalic projecting glutamatergic neuron L6 corticothalamic-projecting glutamatergic cortical neuron Near-projecting glutamatergic cortical neuron L6b glutamatergic cortical neuron L5 extratelencephalic projecting glutamatergic cortical neuron Amygdala excitatory neuron

Middle temporal gyrus Putamen Brodmann (1909) area 24 Bed nucleus of stria terminalis Substantia innominata Agranular insular cortex Corticomedial nuclear complex Brodmann (1909) area 46 Lateral entorhinal cortex Primary motor cortex Amygdala Primary visual cortex Piriform cortex Nucleus accumbens Septal nuclear complex

58-year-old stage 42-year-old stage 29-year-old stage

Normal

Male

Snm3c-seq

Nucleus

Homo sapiens

L2/3-6 intratelencephalic projecting glutamatergic neuron L6 corticothalamic-projecting glutamatergic cortical neuron Near-projecting glutamatergic cortical neuron L6b glutamatergic cortical neuron L5 extratelencephalic projecting glutamatergic cortical neuron Amygdala excitatory neuron

Middle temporal gyrus Putamen Brodmann (1909) area 24 Bed nucleus of stria terminalis Substantia innominata Agranular insular cortex Corticomedial nuclear complex Brodmann (1909) area 46 Lateral entorhinal cortex Primary motor cortex Amygdala Primary visual cortex Piriform cortex Nucleus accumbens Septal nuclear complex

58-year-old stage 42-year-old stage 29-year-old stage

Normal

Male

Snm3c-seq

Nucleus

Homo sapiens

Direct pathway medium spiny neuron Sncg gabaergic interneuron Sst gabaergic interneuron Lamp5 gabaergic interneuron Indirect pathway medium spiny neuron Central nervous system neuron Vip gabaergic interneuron Pvalb gabaergic interneuron Pvalb chandelier gabaergic interneuron

Middle temporal gyrus Putamen Brodmann (1909) area 24 Bed nucleus of stria terminalis Substantia innominata Body of caudate nucleus Agranular insular cortex Globus pallidus Corticomedial nuclear complex Brodmann (1909) area 46 Lateral entorhinal cortex Primary motor cortex Amygdala Primary visual cortex Piriform cortex Nucleus accumbens Septal nuclear complex

58-year-old stage 42-year-old stage 29-year-old stage

Normal

Male

Snm3c-seq

Nucleus

Homo sapiens

Direct pathway medium spiny neuron Sncg gabaergic interneuron Sst gabaergic interneuron Lamp5 gabaergic interneuron Indirect pathway medium spiny neuron Central nervous system neuron Vip gabaergic interneuron Pvalb gabaergic interneuron Pvalb chandelier gabaergic interneuron

Middle temporal gyrus Putamen Brodmann (1909) area 24 Bed nucleus of stria terminalis Substantia innominata Body of caudate nucleus Agranular insular cortex Globus pallidus Corticomedial nuclear complex Brodmann (1909) area 46 Lateral entorhinal cortex Primary motor cortex Amygdala Primary visual cortex Piriform cortex Nucleus accumbens Septal nuclear complex

58-year-old stage 42-year-old stage 29-year-old stage

Normal

Male

Snm3c-seq

Nucleus