Homo sapiens

Retinal rod cell Cone retinal bipolar cell Retinal cone cell Retinal blood vessel endothelial cell Microglial cell Pericyte Mueller cell Amacrine cell Retinal ganglion cell Retinal astrocyte Retina horizontal cell Rod bipolar cell

Perifoveal part of retina Fovea centralis

71-year-old stage 78-year-old stage 63-year-old stage 59-year-old stage

Normal Macular degeneration

Female Male

10x 3' v3

Cell

Homo sapiens

Acinar cell Radial glial cell Schwann cell Classical monocyte Corneal epithelial cell Eye photoreceptor cell Cd4-positive, alpha-beta t cell Muscle cell Non-classical monocyte Macrophage Stromal cell Mast cell Erythroid lineage cell Adipocyte Neutrophil Monocyte Myeloid dendritic cell Keratocyte Retinal blood vessel endothelial cell Microglial cell Fibroblast Endothelial cell Myeloid leukocyte Intermediate monocyte B cell Cd8-positive, alpha-beta t cell Mueller cell Retinal bipolar neuron Plasma cell Erythrocyte Mature nk t cell T cell Retinal pigment epithelial cell Conjunctival epithelial cell Smooth muscle cell Basophil Retinal ganglion cell Retina horizontal cell Natural killer cell

Posterior segment of eyeball Anterior segment of eyeball Sclera Retinal neural layer Conjunctiva Eyelid Eye Chorioretinal region Cornea Lacrimal gland Ocular surface region

57-year-old stage 46-year-old stage 45-year-old stage 40-year-old stage

Normal

Female Male

Smart-seq2 10x 3' v3

Cell

Homo sapiens

Macrophage Mast cell Neutrophil Monocyte B cell Immature nk t cell Dendritic cell T cell

Omental fat pad Subcutaneous adipose tissue

57-year-old stage 71-year-old stage 36-year-old stage 59-year-old stage 54-year-old stage 58-year-old stage 68-year-old stage 51-year-old stage 49-year-old stage 35-year-old stage 53-year-old stage 73-year-old stage 24-year-old stage 29-year-old stage 41-year-old stage

Normal

Female Male

10x 3' v3 Drop-seq

Nucleus Cell

Mus musculus

Endothelial cell of lymphatic vessel Glial cell Interstitial cell of cajal Fibroblast Pericyte Endothelial cell Smooth muscle cell

Normal

10x 3' v2

Homo sapiens

Schwann cell Lymphocyte Macrophage Non-pigmented ciliary epithelial cell Ciliary muscle cell Fibroblast Pigmented ciliary epithelial cell Blood vessel endothelial cell Pericyte Melanocyte

Ciliary body

66-year-old stage 78-year-old stage 47-year-old stage 30-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Mus musculus

Kidney loop of henle thick ascending limb epithelial cell Kidney granular cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney interstitial fibroblast Kidney collecting duct principal cell Macula densa epithelial cell Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Podocyte Endothelial cell Mesangial cell Kidney proximal convoluted tubule epithelial cell

Kidney

6-month-old stage

Normal

Male

Slide-seqv2

Microcebus murinus

Myofibroblast cell Pulmonary alveolar type 1 cell Capillary endothelial cell Erythroid progenitor cell Innate lymphoid cell Endothelial cell of lymphatic vessel Megakaryocyte progenitor cell Cd4-positive, alpha-beta t cell Pulmonary alveolar type 2 cell Club cell Platelet Lymphocyte Macrophage Myelinating schwann cell Mesothelial cell Alveolar macrophage Granulocyte monocyte progenitor cell Brush cell of bronchus Erythroid lineage cell Neutrophil Non-myelinating schwann cell Monocyte Epithelial cell of uterus Vein endothelial cell Vascular associated smooth muscle cell Conventional dendritic cell Fibroblast Hematopoietic precursor cell Pericyte Endothelial cell B cell Cd8-positive, alpha-beta t cell Dendritic cell Plasma cell Mature nk t cell T cell Plasmacytoid dendritic cell Fibroblast of lung Basophil Eosinophil Natural killer cell Endothelial cell of artery Ciliated cell Basal cell of epithelium of bronchus

Lung

Post-juvenile adult stage

Normal

Female Male

Smart-seq2 10x 3' v2

Cell

Homo sapiens

Astrocyte Oligodendrocyte precursor cell Oligodendrocyte Leukocyte Fibroblast Pericyte Endothelial cell Neuron Central nervous system macrophage

Retrosplenial region

50-year-old stage 42-year-old stage 29-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Astrocyte Oligodendrocyte precursor cell Oligodendrocyte Leukocyte Vascular associated smooth muscle cell Fibroblast Pericyte Endothelial cell Neuron Central nervous system macrophage

Globus pallidus

50-year-old stage 42-year-old stage 29-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Astrocyte Oligodendrocyte precursor cell Oligodendrocyte Leukocyte Vascular associated smooth muscle cell Fibroblast Ependymal cell Pericyte Endothelial cell Neuron Central nervous system macrophage

Gray matter of midbrain

50-year-old stage 42-year-old stage

Normal

Male

10x 3' v3

Nucleus

Mus musculus

Type i nk t cell Osteoclast Cd4-positive, alpha-beta t cell Macrophage Cell Monocyte-derived dendritic cell Mast cell Neutrophil Monocyte Conventional dendritic cell B cell Cd8-positive, alpha-beta t cell Dendritic cell Plasma cell Regulatory t cell Plasmacytoid dendritic cell Eosinophil Natural killer cell Gamma-delta t cell

Cutaneous melanoma

10x 5' transcription profiling

Homo sapiens

Astrocyte Oligodendrocyte precursor cell Oligodendrocyte Leukocyte Vascular associated smooth muscle cell Fibroblast Pericyte Endothelial cell Neuron Central nervous system macrophage

Pontine nuclear group

50-year-old stage 42-year-old stage 29-year-old stage

Normal

Male

10x 3' v3

Nucleus