Mus musculus

Kidney loop of henle thick ascending limb epithelial cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney interstitial fibroblast Kidney collecting duct principal cell Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Podocyte Endothelial cell Mesangial cell Kidney proximal convoluted tubule epithelial cell

Kidney

6-month-old stage

Normal

Male

Slide-seqv2

Mus musculus

Myotendinous junction nucleus Schwann cell Macrophage Skeletal muscle satellite stem cell Perineurial cell Adipocyte Tendon cell Type iia muscle cell Fibro/adipogenic progenitor cell Blood vessel endothelial cell Type iib muscle cell Pericyte Type iix muscle cell Smooth muscle cell Neuromuscular junction nucleus Microvascular endothelial cell

Gastrocnemius Skeletal muscle tissue of tibialis anterior

Prime adult stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Kidney loop of henle thick ascending limb epithelial cell Kidney connecting tubule epithelial cell Leukocyte Kidney distal convoluted tubule epithelial cell Kidney interstitial fibroblast Kidney collecting duct principal cell Kidney loop of henle thin descending limb epithelial cell Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Podocyte Pericyte Endothelial cell Kidney loop of henle epithelial cell Mesangial cell Kidney proximal convoluted tubule epithelial cell

Renal medulla

62-year-old stage

Normal

Male

Slide-seqv2

Microcebus murinus

Osteoblast Erythroid progenitor cell Megakaryocyte progenitor cell Cd4-positive, alpha-beta t cell Pulmonary alveolar type 2 cell Endothelial cell of sinusoid Lymphocyte Macrophage Granulocyte monocyte progenitor cell Erythroid lineage cell Adipocyte Neutrophil Monocyte Preosteoblast Conventional dendritic cell Fibroblast Hematopoietic precursor cell B cell Cd8-positive, alpha-beta t cell Dendritic cell Plasma cell Mature nk t cell T cell Plasmacytoid dendritic cell Basophil Eosinophil Natural killer cell Myeloid cell

Bone marrow

Post-juvenile adult stage

Normal

Female Male

Smart-seq2 10x 3' v2

Cell

Homo sapiens

Myofibroblast cell Cd4-positive, alpha-beta memory t cell Macrophage Mast cell Epithelial cell Monocyte Cd8-positive, alpha-beta memory t cell Fibroblast Endothelial cell Neuronal receptor cell B cell Plasma cell Mature nk t cell

Right colon

16-year-old stage 14-year-old stage 15-year-old stage 8-year-old stage 10-year-old stage 17-year-old stage 13-year-old stage 9-year-old stage

Normal

Female Male

10x 3' v3

Cell

Homo sapiens

Capillary endothelial cell Activated cd8-positive, alpha-beta t cell Classical monocyte Cd4-positive, alpha-beta memory t cell Natural t-regulatory cell Cytotoxic t cell Macrophage Mast cell Epithelial cell of lung Dendritic cell, human Granulocyte Conventional dendritic cell Malignant cell Pericyte Plasma cell Plasmacytoid dendritic cell Fibroblast of lung Smooth muscle cell Natural killer cell

Lung parenchyma

Adult stage

Lung adenocarcinoma Squamous cell lung carcinoma

10x gene expression flex

Cell

Mus musculus

Kidney loop of henle thick ascending limb epithelial cell Kidney granular cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney interstitial fibroblast Kidney collecting duct principal cell Macula densa epithelial cell Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Podocyte Endothelial cell Mesangial cell Kidney proximal convoluted tubule epithelial cell

Kidney

13-week-old stage

Normal

Male

Slide-seqv2

Homo sapiens

Cd4-positive helper t cell Malignant cell B cell Cd8-positive, alpha-beta t cell Plasma cell Regulatory t cell Exhausted t cell Myeloid cell

Lung

61-year-old stage

Renal cell carcinoma

Male

Slide-seqv2

Mus musculus

Macrophage Megakaryocyte-erythroid progenitor cell Macrophage dendritic cell progenitor Granulocyte Erythroblast B cell Immature nk t cell Plasma cell Mature nk t cell T cell Proerythroblast Natural killer cell

Spleen

3-month-old stage 20-month-old stage and over 18-month-old stage 4-week-old stage

Normal

Female Male

10x 3' v2

Cell

Homo sapiens

Macrophage Alveolar macrophage Mast cell Monocyte B cell Dendritic cell Plasma cell T cell Natural killer cell

Alveolus of lung

60-year-old stage 65-year-old stage 63-year-old stage 61-year-old stage 73-year-old stage

Normal Pulmonary emphysema

Female Male

10x 3' v3

Cell

Homo sapiens

Astrocyte Oligodendrocyte precursor cell Oligodendrocyte Macrophage Bergmann glial cell Interneuron Endothelial cell T cell Neuron

Cerebellum

Pediatric stage

Normal Pilocytic astrocytoma

Female Male

10x 3' v3

Nucleus

Mus musculus

Pituitary gland cell

Normal

10x 3' v3