Homo sapiens

Radial glial cell Oligodendrocyte precursor cell Glioblast

Diencephalon Cerebellum Telencephalon Brain Pons Midbrain Medulla oblongata Hindbrain

9th week post-fertilization stage 13th week post-fertilization stage 12th week post-fertilization stage 10th week post-fertilization stage Embryonic stage

Normal

Female Male

10x multiome

Nucleus

Mus musculus

Macrophage Mast cell Neutrophil Monocyte B cell Dendritic cell Mature nk t cell T cell

Epididymal fat pad Periovarian fat pad Inguinal fat pad

19-week-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Pulmonary alveolar type 1 cell Pulmonary alveolar type 2 cell Club cell Pulmonary neuroendocrine cell Basal cell Epithelial cell of lung Respiratory tract epithelial cell Neuroendocrine cell Lung secretory cell

Lung

9th week post-fertilization stage 11th week post-fertilization stage 20th week post-fertilization stage 15th week post-fertilization stage 22nd week post-fertilization stage Carnegie stage 19 18th week post-fertilization stage Carnegie stage 16

Normal

Female Male

10x 5' v1

Cell

Homo sapiens

Classical monocyte Innate lymphoid cell Cd4-positive, alpha-beta t cell Platelet Non-classical monocyte Macrophage Naive thymus-derived cd4-positive, alpha-beta t cell Neutrophil Monocyte Myeloid dendritic cell Fibroblast Naive thymus-derived cd8-positive, alpha-beta t cell Hematopoietic precursor cell Hematopoietic stem cell Endothelial cell Intermediate monocyte B cell Cd8-positive, alpha-beta t cell Plasma cell Erythrocyte Regulatory t cell Mature nk t cell T cell Plasmacytoid dendritic cell Basophil Natural killer cell

Spleen

60-year-old stage 45-year-old stage 59-year-old stage 56-year-old stage 61-year-old stage 69-year-old stage

Normal

Female Male

Smart-seq2 10x 5' v2 10x 3' v3

Cell

Homo sapiens

Innate lymphoid cell Macrophage Extravillous trophoblast Syncytiotrophoblast cell Glandular secretory epithelial cell Cd16-negative, cd56-bright natural killer cell, human Monocyte Placental villous trophoblast Granulocyte Conventional dendritic cell Fibroblast Pericyte Endothelial cell Decidual cell Plasma cell T cell Hofbauer cell Decidual natural killer cell, human Cd16-positive, cd56-dim natural killer cell, human

Blood Decidua Placenta

Carnegie stage 14 10th week post-fertilization stage Carnegie stage 22 Carnegie stage 23 Carnegie stage 18

Normal

Female Male

Smart-seq2 10x 3' v2

Cell

Homo sapiens

Best4+ enterocyte Peptic cell Type x enteroendocrine cell Type ec enteroendocrine cell Type g enteroendocrine cell Epithelial cell Enteroendocrine cell Parietal cell Mucous neck cell of gastric gland Enterocyte Foveolar cell of stomach Intestine goblet cell

Body of stomach Pyloric antrum Pylorus Stomach

80-year-old stage 66-year-old stage 70-year-old stage 57-year-old stage 76-year-old stage 62-year-old stage 46-year-old stage 60-year-old stage 44-year-old stage 48-year-old stage 45-year-old stage 65-year-old stage 75-year-old stage 63-year-old stage 17th week post-fertilization stage 59-year-old stage 54-year-old stage 31-year-old stage 15th week post-fertilization stage 56-year-old stage 58-year-old stage 61-year-old stage 51-year-old stage 72-year-old stage Seventh decade stage 69-year-old stage 43-year-old stage 41-year-old stage 55-year-old stage Carnegie stage 16

Normal Gastric cancer

Female Male

10x 5' v2 10x 5' transcription profiling 10x 3' v2

Cell

Homo sapiens

Astrocyte of the cerebral cortex

Middle temporal gyrus

80-year-old stage 85-year-old stage 82-year-old stage 70-year-old stage 77-year-old stage 50-year-old stage 86-year-old stage 60-year-old stage 80 year-old and over stage 89-year-old stage 65-year-old stage 75-year-old stage Adult stage 78-year-old stage 68-year-old stage 72-year-old stage 88-year-old stage 84-year-old stage 69-year-old stage 29-year-old stage 87-year-old stage 81-year-old stage 83-year-old stage

Normal Dementia

Female Male

10x 3' v3 10x multiome

Nucleus

Mus musculus

Germ cell Mural cell Supporting cell Mesothelial cell Epithelial cell Skeletal muscle fiber Hematopoietic cell Leydig cell Sertoli cell Endothelial cell Ovarian surface epithelial cell Interstitial cell of ovary Mesenchymal cell Erythrocyte Granulosa cell Neural cell

Mesonephros Gonad

Theiler stage 24 Theiler stage 21 Theiler stage 26 Theiler stage 20 Theiler stage 19 Theiler stage 27 Theiler stage 22 5-day-old stage

Normal

Female

10x 5' v1 10x 3' v3 10x 3' v2

Cell

Homo sapiens

Pancreatic ductal cell Pancreatic acinar cell Type b pancreatic cell Pancreatic epsilon cell Pancreatic d cell Pp cell Endothelial cell Pancreatic stellate cell Pancreatic a cell

Islet of langerhans

18-year-old stage 21-year-old stage 22-year-old stage 1-year-old stage 27-year-old stage 23-year-old stage 14-year-old stage 15-year-old stage 8-year-old stage 35-year-old stage 10-year-old stage 17-year-old stage 24-year-old stage 13-year-old stage 3-year-old stage 39-year-old stage 4-year-old stage 5-year-old stage 29-year-old stage

Normal Type 1 diabetes mellitus

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Retinal pigment epithelial cell

Chorioretinal region

82-year-old stage 16-year-old stage 77-year-old stage 21-year-old stage 32-year-old stage 50-year-old stage 86-year-old stage 62-year-old stage 46-year-old stage 60-year-old stage 64-year-old stage 25-year-old stage 65-year-old stage 27-year-old stage 71-year-old stage 63-year-old stage 47-year-old stage 58-year-old stage 68-year-old stage 34-year-old stage 53-year-old stage 10-year-old stage 72-year-old stage 30-year-old stage Newborn stage (0-28 days) 69-year-old stage 43-year-old stage 90 year-old and over stage 81-year-old stage 11-year-old stage

Normal

Female Male

10x 5' v2 10x 3' v3

Nucleus

Homo sapiens

Granule cell Inhibitory interneuron Cerebellar granule cell precursor Astrocyte Oligodendrocyte precursor cell Gabaergic interneuron Glial cell Brainstem motor neuron Meningeal macrophage Bergmann glial cell Interneuron Microglial cell Ependymal cell Pericyte Endothelial cell Purkinje cell Choroid plexus epithelial cell

Cerebellum

9th week post-fertilization stage 12th week post-fertilization stage 10th week post-fertilization stage 11th week post-fertilization stage 21st week post-fertilization stage 20th week post-fertilization stage 17th week post-fertilization stage 14th week post-fertilization stage 18th week post-fertilization stage

Normal

Female Male

Split-seq

Cell Nucleus

Homo sapiens

Cycling myeloid cell Kupffer cell Endothelial cell of hepatic sinusoid Platelet Macrophage Mature b cell Cholangiocyte Neutrophil Conventional dendritic cell Hepatocyte Hematopoietic stem cell Plasma cell Erythrocyte T cell Natural killer cell Cycling plasma cell Gamma-delta t cell Mononuclear phagocyte

Right lobe of liver Caudate lobe of liver

Young adult stage 57-year-old stage Prime adult stage Juvenile stage (5-14 yo) 26-year-old stage 69-year-old stage 15-19 year-old Late adult stage Child stage (1-4 yo)

Normal

Female Male

10x 5' v2 10x 5' v1 10x 3' v3 10x 3' v2

Cell