Homo sapiens

Periportal region hepatocyte Blood vessel endothelial cell Natural killer cell Centrilobular region hepatocyte Kupffer cell Midzonal region hepatocyte Inflammatory macrophage Erythroid lineage cell Hepatic stellate cell Endothelial cell of pericentral hepatic sinusoid Cholangiocyte B cell

Caudate lobe of liver

Prime adult stage Young adult stage

Normal

Female Male

10x 3' v3 10x 3' v2

Cell Nucleus

Homo sapiens

Cardiac endothelial cell Endothelial cell of venule Endothelial cell of lymphatic vessel Endothelial cell Colon endothelial cell Endothelial cell of arteriole Endothelial cell of artery Capillary endothelial cell Endothelial cell of vascular tree Vein endothelial cell Retinal blood vessel endothelial cell

Abdominal aorta Adipose tissue Anterior part of tongue Anterior segment of eyeball Aorta Ascending colon Bladder organ Bone marrow Brown adipose tissue Buccal mucosa Cardiac atrium Cardiac ventricle Chorioretinal region Conjunctiva Cornea Coronary artery Crista ampullaris Duodenum Endocrine pancreas Endometrium Exocrine pancreas Eye Eyelid Heart Heart right ventricle Ileum Inferior vena cava Inguinal lymph node Jejunum Kidney Lacrimal gland Large intestine Left coronary artery Left ovary Liver Lung Lymph node Mammary gland Mesenteric lymph node Mucosa of stomach Muscle of abdomen Muscle of pelvic diaphragm Myometrium Ovary Parotid gland Posterior part of tongue Posterior segment of eyeball Prostate gland Right cardiac atrium Right ovary Sclera Sigmoid colon Skin of abdomen Skin of body Skin of chest Small intestine Spleen Stomach Stomach smooth muscle Subcutaneous adipose tissue Sublingual gland Submandibular gland Testis Thoracic aorta Thymus Trachea Uterus Utricle of membranous labyrinth Vasculature

69-year-old stage 37-year-old stage 26-year-old stage 61-year-old stage 38-year-old stage 56-year-old stage 55-year-old stage 57-year-old stage 74-year-old stage 59-year-old stage 67-year-old stage 33-year-old stage 45-year-old stage 46-year-old stage 60-year-old stage 36-year-old stage 40-year-old stage

Normal

Female Male

10x 5' v2 Smart-seq3 Smart-seq2 10x 3' v3

Cell

Homo sapiens

T cell Natural killer cell Mast cell Myeloid cell Plasma cell B cell

Adrenal gland Axilla Bone spine Brain Liver Lung Lymph node Pleural effusion

69-year-old stage 75-year-old stage 65-year-old stage 71-year-old stage 85-year-old stage 68-year-old stage 44-year-old stage 55-year-old stage 84-year-old stage 82-year-old stage 80-year-old stage 57-year-old stage 72-year-old stage 81-year-old stage 74-year-old stage 67-year-old stage 77-year-old stage 64-year-old stage 62-year-old stage 70-year-old stage 78-year-old stage 47-year-old stage 76-year-old stage 79-year-old stage 73-year-old stage

Lung adenocarcinoma Normal Small cell lung carcinoma

Female Male

10x 3' transcription profiling 10x 3' v3 10x 3' v2

Cell

Homo sapiens

Diffuse bipolar 1 cell Diffuse bipolar 4 cell Diffuse bipolar 2 cell Offx cell Rod bipolar cell Invaginating midget bipolar cell Retinal bipolar neuron Flat midget bipolar cell Diffuse bipolar 3a cell On-blue cone bipolar cell Diffuse bipolar 6 cell Giant bipolar cell Diffuse bipolar 3b cell

Chorioretinal region Fovea centralis Macula lutea proper Peripheral region of retina Retinal neural layer

69-year-old stage 65-year-old stage 42-year-old stage 89-year-old stage 71-year-old stage 53-year-old stage 54-year-old stage 68-year-old stage 82-year-old stage 80-year-old stage 74-year-old stage Adult stage 64-year-old stage 86-year-old stage 60-year-old stage 78-year-old stage

Normal

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Dendritic cell, human Stromal cell Natural killer cell Cd8-positive, alpha-beta t cell Macrophage Cd4-positive, alpha-beta t cell B cell Monocyte

Cerebrospinal fluid

69-year-old stage 34-year-old stage 71-year-old stage 61-year-old stage 54-year-old stage 56-year-old stage 55-year-old stage 58-year-old stage 67-year-old stage 45-year-old stage 70-year-old stage 60-year-old stage 63-year-old stage 73-year-old stage 40-year-old stage

Glioblastoma Lymphoma Inflammatory disease Brain cancer

Female Male

10x 5' v2

Cell

Homo sapiens

Intestine goblet cell Best4+ enterocyte Paneth cell Enteroendocrine cell Intestinal crypt stem cell Tuft cell of small intestine Enterocyte Transit amplifying cell Mucous neck cell of gastric gland Foveolar cell of stomach M cell of gut

Duodenal epithelium Duodenum Epithelium of small intestine Ileal epithelium Ileum Ileum lamina propria Jejunum Lamina propria of small intestine Mesenteric lymph node Small intestine

13-year-old stage Sixth decade stage 87-year-old stage 52-year-old stage Fifth decade stage 50-year-old stage 12-year-old stage Third decade stage 9-year-old stage 14-year-old stage Seventh decade stage 67-year-old stage 45-year-old stage 60-year-old stage 31-year-old stage Eighth decade stage Prime adult stage 11-year-old stage 6-year-old stage 10-year-old stage 4-year-old stage

Normal Crohn disease

Female Male

10x 3' v1 10x 5' v2 10x 5' transcription profiling 10x 5' v1 10x 3' v2

Cell

Homo sapiens

Endothelial cell of lymphatic vessel Endothelial cell Mast cell Schwann cell Smooth muscle cell Lymphocyte Adipocyte Macrophage Myeloid cell Fibro/adipogenic progenitor cell Neuron associated cell Mesothelial cell Pericyte Hematopoietic cell

Subcutaneous abdominal adipose tissue Visceral abdominal adipose tissue

66-year-old stage 37-year-old stage 21-year-old stage 26-year-old stage 53-year-old stage 54-year-old stage 28-year-old stage 51-year-old stage 35-year-old stage 62-year-old stage 41-year-old stage 18-year-old stage 47-year-old stage 27-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Natural killer cell Endothelial cell of lymphatic vessel Gamma-delta t cell Endothelial cell Cd8-positive, alpha-beta t cell Cd141-positive myeloid dendritic cell Basal cell Epithelial cell Plasmacytoid dendritic cell Endothelial cell of vascular tree Macrophage Regulatory t cell Keratinocyte Malignant cell Mesenchymal stem cell of adipose tissue B cell Pericyte Granulocyte monocyte progenitor cell Mesenchymal stem cell Naive b cell Myofibroblast cell Neural progenitor cell

Cervical cancer

10x 3' v3

Mus musculus

Mature cd4 single-positive thymocyte Natural killer cell Erythrocyte Gamma-delta t cell Double-positive blast Double-positive, alpha-beta thymocyte Leukocyte Thymic macrophage Mature cd8 single-positive thymocyte Cd8-positive, alpha-beta thymocyte Cd4-positive, alpha-beta thymocyte B cell Double negative thymocyte

Thymus

24-day-old stage 5-week-old stage 4-week-old stage 7-week-old stage 6-week-old stage 10-week-old stage

Normal

Female

10x 3' v3

Cell

Homo sapiens

T cell Central nervous system macrophage Natural killer cell Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Committed oligodendrocyte precursor Cerebellar granule cell Cerebellar inhibitory gabaergic interneuron Ependymal cell Microglial cell Bergmann glial cell B cell Pericyte Neuron Monocyte Purkinje cell Vascular associated smooth muscle cell Astrocyte Unipolar brush cell Fibroblast

Cerebellar vermis

42-year-old stage 29-year-old stage 50-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

T cell Tracheobronchial smooth muscle cell Neutrophil Club cell Dendritic cell, human Natural killer cell Endothelial cell of lymphatic vessel Lung secretory cell Erythrocyte Small pre-b-ii cell Endothelial cell Mature nk t cell Pro-b cell Mast cell Cd8-positive, alpha-beta t cell Pulmonary neuroendocrine cell Platelet Late pro-b cell Pre-b-i cell Group 2 innate lymphoid cell Basal cell B-1a b cell Endothelial cell of artery Capillary endothelial cell Schwann cell Classical monocyte Smooth muscle cell Respiratory tract epithelial cell Plasmacytoid dendritic cell Precursor b cell Lung multiciliated epithelial cell Early lymphoid progenitor Immature schwann cell Bronchus fibroblast of lung B-1b b cell Primitive red blood cell Group 3 innate lymphoid cell Thymocyte T-helper 17 cell Macrophage Cd16-positive, cd56-dim natural killer cell, human Regulatory t cell Large pre-b-ii cell Pulmonary alveolar type 1 cell Promonocyte Bone marrow cell Fibroblast of lung Hematopoietic stem cell Common myeloid progenitor Cd4-positive, alpha-beta t cell Vein endothelial cell Mesenchymal cell Eosinophil Megakaryocyte Squamous epithelial cell Mesothelial cell Pulmonary interstitial fibroblast Pericyte Granulocyte monocyte progenitor cell Promyelocyte Neuron Immature b cell Megakaryocyte-erythroid progenitor cell Epithelial cell of lung Reticulocyte Vascular associated smooth muscle cell Myofibroblast cell Erythroblast Basophil Dendritic cell Cd16-negative, cd56-bright natural killer cell, human Pulmonary alveolar type 2 cell Neural progenitor cell Non-classical monocyte Schwann cell precursor Chondrocyte Cd34-positive, cd56-positive, cd117-positive common innate lymphoid precursor, human

Lung

Carnegie stage 19 15th week post-fertilization stage 20th week post-fertilization stage 9th week post-fertilization stage 18th week post-fertilization stage 22nd week post-fertilization stage Carnegie stage 16 11th week post-fertilization stage

Normal

Female Male

10x 5' v1

Cell

Homo sapiens

Natural killer cell Pro-t cell Hematopoietic precursor cell Erythroid lineage cell Pre-conventional dendritic cell Plasmacytoid dendritic cell Thymocyte Mature b cell Plasma cell Granulocyte monocyte progenitor cell Mature t cell Immature b cell Monocyte Conventional dendritic cell

Thymus

6-month-old stage 10-month-old stage 5-month-old stage 14-month-old stage

Normal

Female Male

10x 3' v2

Cell