Homo sapiens

Pancreatic a cell

Islet of langerhans

66-year-old stage 21-year-old stage 32-year-old stage 50-year-old stage 57-year-old stage 62-year-old stage 52-year-old stage 60-year-old stage 48-year-old stage 45-year-old stage 25-year-old stage 40-year-old stage 37-year-old stage 63-year-old stage 59-year-old stage 54-year-old stage 58-year-old stage 61-year-old stage 34-year-old stage 51-year-old stage 49-year-old stage 42-year-old stage 35-year-old stage 53-year-old stage 30-year-old stage 26-year-old stage 38-year-old stage 55-year-old stage

Normal Prediabetes syndrome Type 2 diabetes mellitus

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Muscle cell Type ii muscle cell Type i muscle cell

Intercostal muscle

Young adult stage Fourth decade stage Eighth decade stage Seventh decade stage Third decade stage Sixth decade stage

Normal

Female Male

10x 3' v3 10x 3' v2

Nucleus

Callithrix jacchus

Neuron

Ventral thalamus Lateral geniculate body Lateral nuclear group of thalamus Dorsal thalamus Thalamic complex Ventral lateral nucleus of thalamus Medial dorsal nucleus of thalamus

Prime adult stage Late adult stage

Normal

Female Male

10x 3' v3

Nucleus

Mus musculus

L4/5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex L2/3-6 intratelencephalic projecting glutamatergic neuron Pyramidal neuron Glutamatergic neuron Astrocyte Oligodendrocyte L2/3 intratelencephalic projecting glutamatergic neuron of the primary motor cortex Vascular leptomeningeal cell (mmus) L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex Sncg gabaergic interneuron L6 corticothalamic-projecting glutamatergic cortical neuron L5/6 near-projecting glutamatergic neuron of the primary motor cortex Sst gabaergic interneuron Lamp5 gabaergic interneuron L6b glutamatergic cortical neuron Corticothalamic-projecting glutamatergic cortical neuron Sst chodl gabaergic interneuron Pericyte Endothelial cell Cajal-retzius cell Hippocampal neuron Central nervous system macrophage L5 extratelencephalic projecting glutamatergic cortical neuron Vip gabaergic interneuron Pvalb gabaergic interneuron Meis2 expressing cortical gabaergic cell Cortical interneuron

Subicular complex Hippocampal formation Posterior parietal association areas Primary somatosensory cortex Medial orbital frontal cortex Temporal cortex Gustatory cortex Agranular insular cortex Anterior cingulate cortex Medial entorhinal cortex Frontal cortex Lateral entorhinal cortex Primary motor cortex Primary visual cortex Auditory cortex Claustrum of brain Retrosplenial region Visual cortex Secondary somatosensory cortex Prefrontal cortex

12-week-old stage 13-week-old stage 7-week-old stage 10-week-old stage 14-week-old stage 15-week-old stage 9-week-old stage 8-week-old stage 11-week-old stage

Normal

Female Male

Smart-seq v4

Cell

Homo sapiens

Kupffer cell Inflammatory macrophage Cholangiocyte Erythroid lineage cell Periportal region hepatocyte Blood vessel endothelial cell B cell Hepatic stellate cell Endothelial cell of pericentral hepatic sinusoid Midzonal region hepatocyte Natural killer cell Centrilobular region hepatocyte

Caudate lobe of liver

Young adult stage Prime adult stage

Normal

Female Male

10x 3' v3 10x 3' v2

Cell Nucleus

Homo sapiens

Capillary endothelial cell Cardiac endothelial cell Endothelial cell of lymphatic vessel Endothelial cell of arteriole Endothelial cell of vascular tree Endothelial cell of venule Retinal blood vessel endothelial cell Vein endothelial cell Endothelial cell Colon endothelial cell Endothelial cell of artery

Posterior part of tongue Posterior segment of eyeball Submandibular gland Stomach smooth muscle Anterior segment of eyeball Coronary artery Ileum Uterus Thymus Vasculature Mesenteric lymph node Liver Skin of abdomen Spleen Parotid gland Brown adipose tissue Testis Right ovary Bladder organ Sublingual gland Lung Inferior vena cava Small intestine Abdominal aorta Ovary Muscle of abdomen Trachea Mammary gland Kidney Muscle of pelvic diaphragm Mucosa of stomach Inguinal lymph node Endometrium Sclera Utricle of membranous labyrinth Jejunum Cardiac ventricle Aorta Adipose tissue Crista ampullaris Subcutaneous adipose tissue Prostate gland Right cardiac atrium Cardiac atrium Skin of chest Conjunctiva Eyelid Eye Chorioretinal region Sigmoid colon Cornea Duodenum Lacrimal gland Myometrium Left coronary artery Bone marrow Thoracic aorta Endocrine pancreas Left ovary Ascending colon Stomach Exocrine pancreas Heart right ventricle Skin of body Buccal mucosa Anterior part of tongue Heart Large intestine Lymph node

57-year-old stage 46-year-old stage 60-year-old stage 45-year-old stage 74-year-old stage 33-year-old stage 67-year-old stage 40-year-old stage 37-year-old stage 36-year-old stage 59-year-old stage 56-year-old stage 61-year-old stage 26-year-old stage 69-year-old stage 38-year-old stage 55-year-old stage

Normal

Female Male

Smart-seq2 10x 5' v2 10x 3' v3 Smart-seq3

Cell

Homo sapiens

Mast cell B cell Plasma cell T cell Natural killer cell Myeloid cell

Axilla Adrenal gland Liver Lung Brain Pleural effusion Bone spine Lymph node

80-year-old stage 85-year-old stage 82-year-old stage 79-year-old stage 70-year-old stage 77-year-old stage 57-year-old stage 76-year-old stage 62-year-old stage 44-year-old stage 64-year-old stage 74-year-old stage 65-year-old stage 67-year-old stage 75-year-old stage 71-year-old stage 78-year-old stage 47-year-old stage 68-year-old stage 72-year-old stage 73-year-old stage 84-year-old stage 69-year-old stage 81-year-old stage 55-year-old stage

Small cell lung carcinoma Normal Lung adenocarcinoma

Female Male

10x 3' v3 10x 3' v2 10x 3' transcription profiling

Cell

Homo sapiens

Diffuse bipolar 4 cell Flat midget bipolar cell Offx cell Diffuse bipolar 2 cell Diffuse bipolar 3a cell Diffuse bipolar 3b cell Invaginating midget bipolar cell Giant bipolar cell Diffuse bipolar 6 cell Diffuse bipolar 1 cell Retinal bipolar neuron On-blue cone bipolar cell Rod bipolar cell

Peripheral region of retina Fovea centralis Retinal neural layer Chorioretinal region Macula lutea proper

80-year-old stage 82-year-old stage 86-year-old stage 60-year-old stage 64-year-old stage 89-year-old stage 74-year-old stage 65-year-old stage 71-year-old stage Adult stage 78-year-old stage 54-year-old stage 68-year-old stage 42-year-old stage 53-year-old stage 69-year-old stage

Normal

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Cd4-positive, alpha-beta t cell Macrophage Stromal cell Monocyte Dendritic cell, human B cell Cd8-positive, alpha-beta t cell Natural killer cell

Cerebrospinal fluid

70-year-old stage 60-year-old stage 45-year-old stage 67-year-old stage 40-year-old stage 71-year-old stage 63-year-old stage 54-year-old stage 56-year-old stage 58-year-old stage 61-year-old stage 34-year-old stage 73-year-old stage 69-year-old stage 55-year-old stage

Lymphoma Glioblastoma Brain cancer Inflammatory disease

Female Male

10x 5' v2

Cell

Homo sapiens

Best4+ enterocyte Transit amplifying cell Intestinal crypt stem cell Paneth cell Enteroendocrine cell Tuft cell of small intestine Mucous neck cell of gastric gland Enterocyte Foveolar cell of stomach M cell of gut Intestine goblet cell

Duodenal epithelium Ileum Ileum lamina propria Mesenteric lymph node Small intestine Jejunum Epithelium of small intestine Lamina propria of small intestine Duodenum Ileal epithelium

50-year-old stage Prime adult stage 52-year-old stage 60-year-old stage 45-year-old stage 67-year-old stage Eighth decade stage 14-year-old stage 6-year-old stage Fifth decade stage 31-year-old stage 10-year-old stage 13-year-old stage Seventh decade stage 12-year-old stage 4-year-old stage 9-year-old stage Third decade stage 87-year-old stage Sixth decade stage 11-year-old stage

Normal Crohn disease

Female Male

10x 5' v2 10x 5' v1 10x 5' transcription profiling 10x 3' v1 10x 3' v2

Cell

Homo sapiens

Schwann cell Endothelial cell of lymphatic vessel Lymphocyte Macrophage Mesothelial cell Mast cell Neuron associated cell Adipocyte Hematopoietic cell Fibro/adipogenic progenitor cell Pericyte Endothelial cell Smooth muscle cell Myeloid cell

Subcutaneous abdominal adipose tissue Visceral abdominal adipose tissue

66-year-old stage 18-year-old stage 21-year-old stage 62-year-old stage 27-year-old stage 37-year-old stage 28-year-old stage 54-year-old stage 47-year-old stage 51-year-old stage 35-year-old stage 53-year-old stage 26-year-old stage 41-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Myofibroblast cell Naive b cell Mesenchymal stem cell Endothelial cell of lymphatic vessel Macrophage Granulocyte monocyte progenitor cell Cd141-positive myeloid dendritic cell Basal cell Endothelial cell of vascular tree Epithelial cell Neural progenitor cell Malignant cell Pericyte Endothelial cell B cell Cd8-positive, alpha-beta t cell Regulatory t cell Mesenchymal stem cell of adipose tissue Plasmacytoid dendritic cell Keratinocyte Natural killer cell Gamma-delta t cell

Cervical cancer

10x 3' v3