Homo sapiens

Smooth muscle cell of the pulmonary artery Capillary endothelial cell Innate lymphoid cell Endothelial cell of lymphatic vessel Glial cell T-helper 2 cell Macrophage Naive thymus-derived cd4-positive, alpha-beta t cell Mesothelial cell Endocardial cell Mucosal invariant t cell Mast cell Atrioventricular bundle cell Cd16-negative, cd56-bright natural killer cell, human Adipocyte Neutrophil Monocyte Cd14-positive monocyte Cd8-positive, alpha-beta cytotoxic t cell Vein endothelial cell Dendritic cell, human Regular atrial cardiac myocyte Pericyte Endothelial cell Cardiac pacemaker cell of sinoatrial node Regular ventricular cardiac myocyte B cell Cd8-positive, alpha-beta t cell Activated cd4-positive, alpha-beta t cell Plasma cell Fibroblast of cardiac tissue Mature nk t cell Cd14-low, cd16-positive monocyte Smooth muscle cell Endothelial cell of artery Cd16-positive, cd56-dim natural killer cell, human

Interventricular septum Apex of heart Heart left ventricle Sinoatrial node Left cardiac atrium Atrioventricular node Right cardiac atrium Heart right ventricle

Eighth decade stage Fifth decade stage Seventh decade stage Third decade stage Sixth decade stage

Normal

Female Male

Visium spatial gene expression v1

Mus musculus

Retinal rod cell Retinal cone cell Pituitary gland cell Photoreceptor cell Epithelial cell of pancreas Retinal progenitor cell Pinealocyte Cochlea auditory hair cell Retinal bipolar neuron Iris pigment epithelial cell Neural cell

Embryo

Theiler stage 23 Theiler stage 24 Theiler stage 21 Theiler stage 13 Theiler stage 25 Theiler stage 17 Theiler stage 16 Theiler stage 26 Theiler stage 18 Theiler stage 20 Theiler stage 19 Theiler stage 27 Theiler stage 14 Theiler stage 15 Theiler stage 22

Normal

Female Male

Sci-rna-seq3

Nucleus

Homo sapiens

Endothelial cell of lymphatic vessel Fibroblast Blood vessel endothelial cell Salivary gland glandular cell Pericyte Squamous epithelial cell

Oropharynx Mouth floor Gingiva of lower jaw Mandible Tongue Hypopharynx Larynx Oral cavity Alveolar ridge of mandible Buccal mucosa

80-year-old stage 66-year-old stage 70-year-old stage 18-year-old stage 77-year-old stage 32-year-old stage 57-year-old stage 62-year-old stage 64-year-old stage 74-year-old stage 65-year-old stage 67-year-old stage 75-year-old stage 54-year-old stage 56-year-old stage 58-year-old stage 61-year-old stage 51-year-old stage 35-year-old stage 53-year-old stage 72-year-old stage 73-year-old stage 69-year-old stage 55-year-old stage

Head and neck squamous cell carcinoma

Female Male

10x 3' v3 10x 5' transcription profiling 10x 3' v2

Cell

Homo sapiens

Near-projecting glutamatergic cortical neuron L6b glutamatergic cortical neuron Corticothalamic-projecting glutamatergic cortical neuron L5 extratelencephalic projecting glutamatergic cortical neuron

Middle temporal gyrus Primary somatosensory cortex Anterior cingulate cortex Primary auditory cortex Dorsolateral prefrontal cortex Primary motor cortex Primary visual cortex Angular gyrus

50-year-old stage 60-year-old stage 42-year-old stage 43-year-old stage 29-year-old stage Sixth decade stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Common myeloid progenitor Naive b cell Erythroid progenitor cell Classical monocyte Non-classical monocyte Lymphocyte Macrophage Small pre-b-ii cell Megakaryocyte Hematopoietic stem cell Plasmacytoid dendritic cell, human Dendritic cell Plasma cell Memory b cell Precursor b cell Natural killer cell

Bone marrow

82-year-old stage 70-year-old stage 60-year-old stage 44-year-old stage 67-year-old stage 71-year-old stage 61-year-old stage 51-year-old stage 53-year-old stage 73-year-old stage 69-year-old stage 55-year-old stage

Normal B-cell non-hodgkin lymphoma

Female Male

10x 5' v1

Cell

Homo sapiens

Endothelial cell of lymphatic vessel Muscle cell Macrophage Mast cell Endothelial cell of vascular tree Monocyte Skeletal muscle fiber Fibroblast Skeletal muscle satellite cell T cell Smooth muscle cell Chondrocyte Neural cell

Tendon of quadriceps femoris Calcaneal tendon

13th week post-fertilization stage 21st week post-fertilization stage 18th week post-fertilization stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Central nervous system macrophage

Inferior frontal gyrus Middle temporal gyrus Putamen Brodmann (1909) area 24 Cerebellar vermis Posterior parahippocampal gyrus Anterior olfactory nucleus Brodmann (1909) area 38 Pretectal region Subicular complex Gray matter of midbrain Brodmann (1909) area 14 Brodmann (1909) area 19 Inferior temporal gyrus Hypothalamus Brodmann (1909) area 32 Cerebrocerebellum Dentate gyrus of hippocampal formation Lateral geniculate body Bed nucleus of stria terminalis Median tuberal portion Brodmann (1909) area 13 Primary somatosensory cortex Medial geniculate body Preoptic area Substantia innominata Perirhinal cortex Body of caudate nucleus Extrastriate cortex Lateral nuclear group of thalamus Dorsal tegmental nucleus Brodmann (1909) area 23 Centromedian nucleus of thalamus Brodmann (1909) area 35 Epithalamus Substantia nigra Central amygdaloid nucleus Rostral ca3 Granular insular cortex Agranular insular cortex Globus pallidus Basolateral amygdaloid nuclear complex Parabrachial nucleus Ventral anterior nucleus of thalamus Nucleus of dorsal thalamus Anterior cortical amygdaloid nucleus Anterior nuclear group Brodmann (1909) area 43 Primary auditory cortex Medial entorhinal cortex Red nucleus Corticomedial nuclear complex Lateral posterior nucleus of thalamus Brodmann (1909) area 46 Nucleus of medulla oblongata Supraoptic nucleus Uncal ca1 Cerebellar nuclear complex Temporal fusiform gyrus Lateral entorhinal cortex Brodmann (1909) area 25 Midbrain nucleus Primary motor cortex Pulvinar nucleus Pontine tegmentum Primary visual cortex Subthalamic nucleus Spinal cord Superior parietal cortex Hippocampal field Inferior olivary complex Piriform cortex Lateral amygdaloid nucleus Brodmann (1909) area 40 Claustrum of brain Midbrain tectum Mammillary body Pontine reticular formation Pontine nuclear group Medial dorsal nucleus of thalamus Retrosplenial region Nucleus accumbens Medial zone of hypothalamus Intralaminar nuclear group Accessory basal amygdaloid nucleus Superior temporal gyrus Septal nuclear complex Cuneus cortex

50-year-old stage 60-year-old stage 42-year-old stage 29-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Inhibitory interneuron Neuron

Substantia nigra pars compacta

91-year-old stage 82-year-old stage 79-year-old stage 70-year-old stage 76-year-old stage 89-year-old stage 74-year-old stage 92-year-old stage 75-year-old stage 78-year-old stage 49-year-old stage 90-year-old stage 83-year-old stage

Normal Lewy body dementia Parkinson disease

Female Male

10x 3' v3

Nucleus

Homo sapiens

Naive b cell Classical monocyte Platelet Non-classical monocyte Lymphocyte Naive thymus-derived cd4-positive, alpha-beta t cell Mucosal invariant t cell Transitional stage b cell Cd16-negative, cd56-bright natural killer cell, human Neutrophil Double negative thymocyte Plasmablast Conventional dendritic cell Naive thymus-derived cd8-positive, alpha-beta t cell Central memory cd4-positive, alpha-beta t cell Effector memory cd8-positive, alpha-beta t cell Plasmacytoid dendritic cell, human Regulatory t cell Memory b cell Natural killer cell Gamma-delta t cell Immature neutrophil

Blood

Fourth decade stage Eighth decade stage 27-year-old stage Adult stage Fifth decade stage Seventh decade stage Third decade stage 29-year-old stage Sixth decade stage

Normal Covid-19

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Pvalb gabaergic interneuron

Middle temporal gyrus

80-year-old stage 85-year-old stage 82-year-old stage 70-year-old stage 77-year-old stage 50-year-old stage 86-year-old stage 60-year-old stage 80 year-old and over stage 89-year-old stage 65-year-old stage 75-year-old stage Adult stage 78-year-old stage 68-year-old stage 72-year-old stage 88-year-old stage 84-year-old stage 69-year-old stage 43-year-old stage 29-year-old stage 87-year-old stage 81-year-old stage 83-year-old stage

Normal Dementia

Female Male

10x 3' v3 10x multiome

Nucleus

Homo sapiens

Ventricular cardiac muscle cell

Apex of heart Heart left ventricle

19-year-old stage 70-year-old stage 21-year-old stage 32-year-old stage 52-year-old stage 64-year-old stage 25-year-old stage Eighth decade stage 27-year-old stage 28-year-old stage Fifth decade stage 31-year-old stage 61-year-old stage 49-year-old stage 30-year-old stage 24-year-old stage Seventh decade stage 26-year-old stage Third decade stage 29-year-old stage 38-year-old stage 55-year-old stage Sixth decade stage

Normal Myocarditis

Female Male

10x 3' v3 10x 3' v2

Nucleus

Homo sapiens

Myofibroblast cell Transit amplifying cell Capillary endothelial cell Igg plasma cell Endothelial cell of lymphatic vessel Glial cell Iga plasma cell Macrophage Epithelial fate stem cell Mast cell Epithelial cell Paneth cell Monocyte Enteroendocrine cell Vein endothelial cell Fibroblast Intestinal tuft cell Endothelial cell B cell Dendritic cell T cell Plasmacytoid dendritic cell Igm plasma cell Endothelial cell of artery Germinal center b cell Goblet cell

Functional colonic disease

10x 3' v2