Homo sapiens

Myofibroblast cell Transit amplifying cell Capillary endothelial cell Igg plasma cell Endothelial cell of lymphatic vessel Glial cell Iga plasma cell Macrophage Epithelial fate stem cell Mast cell Epithelial cell Paneth cell Monocyte Enteroendocrine cell Vein endothelial cell Fibroblast Intestinal tuft cell Endothelial cell B cell Dendritic cell T cell Plasmacytoid dendritic cell Igm plasma cell Endothelial cell of artery Germinal center b cell Goblet cell

Lamina propria of small intestine

16-year-old stage 18-year-old stage 22-year-old stage 14-year-old stage 15-year-old stage 10-year-old stage 17-year-old stage 13-year-old stage 12-year-old stage 11-year-old stage

Digestive system disorder

Female Male

10x 3' v2

Cell

Homo sapiens

Kupffer cell Cd4-positive, alpha-beta t cell Macrophage Mature b cell Mast cell Endothelial cell of periportal hepatic sinusoid Neutrophil Monocyte Intrahepatic cholangiocyte Periportal region hepatocyte Vein endothelial cell Conventional dendritic cell Fibroblast Hepatocyte Cd8-positive, alpha-beta t cell Hepatic stellate cell Hepatic pit cell Plasma cell Endothelial cell of pericentral hepatic sinusoid Erythrocyte T cell Plasmacytoid dendritic cell Midzonal region hepatocyte Natural killer cell Endothelial cell of artery Centrilobular region hepatocyte

Caudate lobe of liver

Young adult stage Prime adult stage Postnatal stage Late adult stage

Normal Primary sclerosing cholangitis Primary biliary cholangitis

Female Male

10x 5' v2 10x 5' v1

Cell

Mus musculus

Regulatory t cell T cell Activated cd4-negative, cd8-negative type i nk t cell Natural killer cell

Embryo

Theiler stage 23 Theiler stage 24 Theiler stage 21 Theiler stage 25 Theiler stage 16 Theiler stage 26 Theiler stage 12 Theiler stage 18 Theiler stage 20 Theiler stage 19 Theiler stage 27 Theiler stage 14 Theiler stage 22

Normal

Female Male

Sci-rna-seq3

Nucleus

Macaca mulatta

L2/3-6 intratelencephalic projecting glutamatergic neuron Caudal ganglionic eminence derived interneuron Cerebral cortex endothelial cell Vascular leptomeningeal cell Oligodendrocyte precursor cell Oligodendrocyte Astrocyte of the cerebral cortex Sncg gabaergic interneuron Near-projecting glutamatergic cortical neuron Sst gabaergic interneuron Microglial cell Lamp5 gabaergic interneuron L6b glutamatergic cortical neuron Corticothalamic-projecting glutamatergic cortical neuron L5 extratelencephalic projecting glutamatergic cortical neuron Vip gabaergic interneuron Pvalb gabaergic interneuron Pvalb chandelier gabaergic interneuron

Middle temporal gyrus

Prime adult stage

Normal

Female

10x 3' v3

Nucleus

Homo sapiens

L2/3 intratelencephalic projecting glutamatergic neuron Caudal ganglionic eminence derived interneuron Brain vascular cell Glutamatergic neuron Hippocampal ca1-3 neuron Astrocyte Oligodendrocyte precursor cell Oligodendrocyte Medial ganglionic eminence derived gabaergic interneuron Dentate gyrus neuron Committed oligodendrocyte precursor L5/6 near-projecting glutamatergic neuron L5 intratelencephalic projecting glutamatergic neuron Microglial cell Lamp5 gabaergic interneuron Fibroblast Amygdala excitatory neuron

Hippocampal formation Temporal cortex Amygdala Frontal lobe

14-year-old stage 6-year-old stage 15-year-old stage 10-year-old stage 9-year-old stage 11-year-old stage

Normal

Female Male

10x multiome

Nucleus

Homo sapiens

Myofibroblast cell Myoepithelial cell Pulmonary alveolar type 1 cell Capillary endothelial cell Naive b cell Ciliated epithelial cell Igg plasma cell Simple columnar epithelial cell Innate lymphoid cell Cd4-positive, alpha-beta memory t cell Cd4-positive, alpha-beta t cell Pulmonary alveolar type 2 cell Club cell Iga plasma cell Macrophage Myelinating schwann cell Mesothelial cell Alveolar macrophage Mucosal invariant t cell Lymph node lymphatic vessel endothelial cell Mast cell Tracheobronchial smooth muscle cell Non-myelinating schwann cell Tracheobronchial chondrocyte Megakaryocyte Pulmonary artery endothelial cell Cd14-positive monocyte Blood vessel smooth muscle cell Respiratory tract epithelial cell Plasmablast Tracheobronchial serous cell Vein endothelial cell Cd8-positive, alpha-beta memory t cell Conventional dendritic cell Fibroblast Effector memory cd8-positive, alpha-beta t cell Pericyte Deuterosomal cell Lung macrophage Lung pericyte Erythrocyte Regulatory t cell Mature nk t cell Memory b cell Plasmacytoid dendritic cell Cd14-low, cd16-positive monocyte Mucus secreting cell Neuroendocrine cell Fibroblast of lung Smooth muscle cell Respiratory basal cell Pulmonary ionocyte Natural killer cell Chondrocyte Endothelial cell of artery Gamma-delta t cell Goblet cell

Lung Bronchus Upper lobe of left lung Trachea Lower lobe of left lung

64-year-old stage 75-year-old stage Post-juvenile adult stage Seventh decade stage 29-year-old stage

Normal

Female Male Mixed sex

10x genomics v3 10x genomics v2

Mus musculus

Macrophage Microglial cell Fibroblast Pericyte Endothelial cell Dendritic cell T cell Smooth muscle cell Natural killer cell Choroid plexus epithelial cell

Normal Alzheimer disease

10x 3' v3

Homo sapiens

Endothelial cell of lymphatic vessel Cd4-positive, alpha-beta t cell Stratified epithelial cell Stromal cell Mast cell Epithelial cell Immature b cell Cd8-positive, alpha-beta cytotoxic t cell Blood vessel endothelial cell B cell Cd8-positive, alpha-beta t cell Dendritic cell Mucus secreting cell Epithelial cell of stratum germinativum of esophagus Mononuclear phagocyte

Epithelium of esophagus

Fourth decade stage Fifth decade stage Seventh decade stage Sixth decade stage

Normal

Female Male

10x 3' v2

Cell

Danio rerio

Glutamatergic neuron Glial cell Neuroblast (sensu vertebrata) Neural progenitor cell Neuron

Ventricular zone Forebrain Multicellular anatomical structure Spinal cord Hindbrain

Pharyngula:high-pec Segmentation:26+ somites Pharyngula:prim-5 Hatching:pec-fin Hatching:long-pec Segmentation:20-25 somites Segmentation:14-19 somites Larval:protruding-mouth Pharyngula:prim-15 Pharyngula:prim-25

Normal

Sci-rna-seq3

Nucleus

Homo sapiens

Muscle cell Type ii muscle cell Type i muscle cell

Intercostal muscle

Young adult stage Fourth decade stage Eighth decade stage Seventh decade stage Third decade stage Sixth decade stage

Normal

Female Male

10x 3' v3 10x 3' v2

Cell Nucleus

Homo sapiens

Astrocyte of the cerebral cortex

Dorsolateral prefrontal cortex

80-year-old stage 85-year-old stage 82-year-old stage 70-year-old stage 77-year-old stage 50-year-old stage 86-year-old stage 80 year-old and over stage 89-year-old stage 75-year-old stage 78-year-old stage 68-year-old stage 42-year-old stage 72-year-old stage 88-year-old stage 84-year-old stage 69-year-old stage 29-year-old stage 87-year-old stage 81-year-old stage 83-year-old stage

Normal Dementia

Female Male

10x 3' v3 10x multiome

Nucleus

Callithrix jacchus

Gabaergic neuron

Dorsolateral prefrontal cortex Brodmann (1909) area 25 Prefrontal cortex

Prime adult stage Late adult stage

Normal

Female Male

10x 3' v3

Nucleus