Homo sapiens

Natural killer cell Erythroid progenitor cell Small pre-b-ii cell Classical monocyte Plasmacytoid dendritic cell, human Precursor b cell Lymphocyte Macrophage Memory b cell Hematopoietic stem cell Common myeloid progenitor Plasma cell Megakaryocyte Naive b cell Dendritic cell Non-classical monocyte

Bone marrow

69-year-old stage 71-year-old stage 53-year-old stage 61-year-old stage 44-year-old stage 55-year-old stage 82-year-old stage 51-year-old stage 67-year-old stage 70-year-old stage 60-year-old stage 73-year-old stage

B-cell non-hodgkin lymphoma Normal

Female Male

10x 5' v1

Cell

Homo sapiens

T cell Muscle cell Endothelial cell of lymphatic vessel Mast cell Smooth muscle cell Skeletal muscle satellite cell Neural cell Endothelial cell of vascular tree Macrophage Monocyte Fibroblast Skeletal muscle fiber Chondrocyte

Calcaneal tendon Tendon of quadriceps femoris

21st week post-fertilization stage 13th week post-fertilization stage 18th week post-fertilization stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Central nervous system macrophage Microglial cell

Brodmann (1909) area 13 Brodmann (1909) area 14 Brodmann (1909) area 19 Brodmann (1909) area 23 Brodmann (1909) area 24 Brodmann (1909) area 25 Brodmann (1909) area 32 Brodmann (1909) area 35 Brodmann (1909) area 38 Brodmann (1909) area 40 Brodmann (1909) area 43 Brodmann (1909) area 46 Accessory basal amygdaloid nucleus Agranular insular cortex Anterior cortical amygdaloid nucleus Anterior nuclear group Anterior olfactory nucleus Basolateral amygdaloid nuclear complex Bed nucleus of stria terminalis Body of caudate nucleus Central amygdaloid nucleus Centromedian nucleus of thalamus Cerebellar nuclear complex Cerebellar vermis Cerebrocerebellum Claustrum of brain Corticomedial nuclear complex Cuneus cortex Dentate gyrus of hippocampal formation Dorsal tegmental nucleus Epithalamus Extrastriate cortex Globus pallidus Granular insular cortex Gray matter of midbrain Hippocampal field Hypothalamus Inferior frontal gyrus Inferior olivary complex Inferior temporal gyrus Intralaminar nuclear group Lateral amygdaloid nucleus Lateral entorhinal cortex Lateral geniculate body Lateral nuclear group of thalamus Lateral posterior nucleus of thalamus Mammillary body Medial dorsal nucleus of thalamus Medial entorhinal cortex Medial geniculate body Medial zone of hypothalamus Median tuberal portion Midbrain nucleus Midbrain tectum Middle temporal gyrus Nucleus accumbens Nucleus of dorsal thalamus Nucleus of medulla oblongata Parabrachial nucleus Perirhinal cortex Piriform cortex Pontine nuclear group Pontine reticular formation Pontine tegmentum Posterior parahippocampal gyrus Preoptic area Pretectal region Primary auditory cortex Primary motor cortex Primary somatosensory cortex Primary visual cortex Pulvinar nucleus Putamen Red nucleus Retrosplenial region Rostral ca3 Septal nuclear complex Spinal cord Subicular complex Substantia innominata Substantia nigra Subthalamic nucleus Superior parietal cortex Superior temporal gyrus Supraoptic nucleus Temporal fusiform gyrus Uncal ca1 Ventral anterior nucleus of thalamus

42-year-old stage 29-year-old stage 50-year-old stage 60-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Inhibitory interneuron Neuron

Substantia nigra pars compacta

75-year-old stage 91-year-old stage 89-year-old stage 92-year-old stage 82-year-old stage 90-year-old stage 74-year-old stage 49-year-old stage 70-year-old stage 78-year-old stage 76-year-old stage 79-year-old stage 83-year-old stage

Parkinson disease Normal Lewy body dementia

Female Male

10x 3' v3

Nucleus

Homo sapiens

Central memory cd4-positive, alpha-beta t cell Neutrophil Natural killer cell Gamma-delta t cell Platelet Classical monocyte Plasmacytoid dendritic cell, human Lymphocyte Naive thymus-derived cd8-positive, alpha-beta t cell Memory b cell Regulatory t cell Plasmablast Naive thymus-derived cd4-positive, alpha-beta t cell Mucosal invariant t cell Transitional stage b cell Naive b cell Double negative thymocyte Conventional dendritic cell Cd16-negative, cd56-bright natural killer cell, human Effector memory cd8-positive, alpha-beta t cell Immature neutrophil Non-classical monocyte

Blood

Sixth decade stage 29-year-old stage Fifth decade stage Third decade stage Seventh decade stage Adult stage Fourth decade stage Eighth decade stage 27-year-old stage

Covid-19 Normal

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Pvalb gabaergic interneuron

Middle temporal gyrus

69-year-old stage 75-year-old stage 65-year-old stage 89-year-old stage 43-year-old stage 87-year-old stage 85-year-old stage 88-year-old stage 68-year-old stage 29-year-old stage 84-year-old stage 82-year-old stage 50-year-old stage 80-year-old stage 72-year-old stage 81-year-old stage 80 year-old and over stage Adult stage 77-year-old stage 86-year-old stage 70-year-old stage 60-year-old stage 78-year-old stage 83-year-old stage

Normal Dementia

Female Male

10x multiome 10x 3' v3

Nucleus

Homo sapiens

Ventricular cardiac muscle cell

Apex of heart Heart left ventricle

21-year-old stage 26-year-old stage Sixth decade stage 61-year-old stage 52-year-old stage 30-year-old stage 29-year-old stage 38-year-old stage Fifth decade stage 55-year-old stage 28-year-old stage Third decade stage 49-year-old stage 24-year-old stage Seventh decade stage 25-year-old stage 32-year-old stage 64-year-old stage 70-year-old stage 31-year-old stage 19-year-old stage Eighth decade stage 27-year-old stage

Myocarditis Normal

Female Male

10x 3' v3 10x 3' v2

Nucleus

Homo sapiens

T cell Germinal center b cell Igm plasma cell Endothelial cell of lymphatic vessel Endothelial cell Mast cell Iga plasma cell Endothelial cell of artery Capillary endothelial cell Paneth cell Epithelial cell Intestinal tuft cell Plasmacytoid dendritic cell Igg plasma cell Enteroendocrine cell Goblet cell Macrophage Glial cell Vein endothelial cell Transit amplifying cell B cell Monocyte Myofibroblast cell Epithelial fate stem cell Fibroblast Dendritic cell

Lamina propria of small intestine

13-year-old stage 17-year-old stage 15-year-old stage 12-year-old stage 14-year-old stage 16-year-old stage 18-year-old stage 22-year-old stage 11-year-old stage 10-year-old stage

Digestive system disorder

Female Male

10x 3' v2

Cell

Homo sapiens

T cell Germinal center b cell Igm plasma cell Endothelial cell of lymphatic vessel Endothelial cell Mast cell Iga plasma cell Endothelial cell of artery Capillary endothelial cell Paneth cell Epithelial cell Intestinal tuft cell Plasmacytoid dendritic cell Igg plasma cell Enteroendocrine cell Goblet cell Macrophage Glial cell Vein endothelial cell Transit amplifying cell B cell Monocyte Myofibroblast cell Epithelial fate stem cell Fibroblast Dendritic cell

Functional colonic disease

10x 3' v2

Homo sapiens

T cell Neutrophil Periportal region hepatocyte Hepatocyte Endothelial cell of periportal hepatic sinusoid Natural killer cell Hepatic pit cell Erythrocyte Centrilobular region hepatocyte Kupffer cell Midzonal region hepatocyte Mast cell Cd8-positive, alpha-beta t cell Endothelial cell of artery Plasmacytoid dendritic cell Hepatic stellate cell Macrophage Endothelial cell of pericentral hepatic sinusoid Mature b cell Plasma cell Cd4-positive, alpha-beta t cell Vein endothelial cell Monocyte Conventional dendritic cell Fibroblast Intrahepatic cholangiocyte

Caudate lobe of liver

Late adult stage Postnatal stage Prime adult stage Young adult stage

Primary sclerosing cholangitis Primary biliary cholangitis Normal

Female Male

10x 5' v2 10x 5' v1

Cell

Mus musculus

T cell Natural killer cell Regulatory t cell Activated cd4-negative, cd8-negative type i nk t cell

Embryo

Theiler stage 22 Theiler stage 27 Theiler stage 24 Theiler stage 18 Theiler stage 25 Theiler stage 14 Theiler stage 16 Theiler stage 19 Theiler stage 26 Theiler stage 20 Theiler stage 12 Theiler stage 21 Theiler stage 23

Normal

Female Male

Sci-rna-seq3

Nucleus

Macaca mulatta

Oligodendrocyte precursor cell Oligodendrocyte Vascular leptomeningeal cell Pvalb chandelier gabaergic interneuron Lamp5 gabaergic interneuron Microglial cell Vip gabaergic interneuron L2/3-6 intratelencephalic projecting glutamatergic neuron L5 extratelencephalic projecting glutamatergic cortical neuron L6b glutamatergic cortical neuron Pvalb gabaergic interneuron Near-projecting glutamatergic cortical neuron Cerebral cortex endothelial cell Caudal ganglionic eminence derived interneuron Sncg gabaergic interneuron Astrocyte of the cerebral cortex Sst gabaergic interneuron Corticothalamic-projecting glutamatergic cortical neuron

Middle temporal gyrus

Prime adult stage

Normal

Female

10x 3' v3

Nucleus