Mus musculus

Capillary endothelial cell Endothelial cell of lymphatic vessel Muscle cell Macrophage Myelinating schwann cell Skeletal muscle satellite stem cell Type ii muscle cell Adipocyte Neutrophil Non-myelinating schwann cell Monocyte Tendon cell Type iia muscle cell Vein endothelial cell Fibroblast Type iib muscle cell Pericyte B cell Erythrocyte Extrafusal muscle fiber Smooth muscle cell Endothelial cell of artery Type i muscle cell

Hindlimb muscle

3-month-old stage 19-month-old stage

Normal

Male

10x 3' v2

Cell Nucleus

Homo sapiens

Innate lymphoid cell Club cell Pulmonary neuroendocrine cell Cytotoxic t cell Non-classical monocyte Ionocyte Macrophage Endocardial cell Alveolar type 1 fibroblast cell Stromal cell Mast cell Basal cell Cd4-positive helper t cell Epithelial cell of lung Respiratory tract multiciliated cell Monocyte Respiratory tract goblet cell Dendritic cell, human Nasal mucosa goblet cell Pericyte B cell Cd8-positive, alpha-beta t cell Bronchial goblet cell Plasma cell Secretory cell Mucus secreting cell of bronchus submucosal gland Alveolar adventitial fibroblast Fibroblast of lung Natural killer cell Respiratory tract suprabasal cell Mature t cell

Respiratory tube Carina of trachea

33-year-old stage 27-year-old stage Adult stage Fifth decade stage 31-year-old stage 35-year-old stage 30-year-old stage 24-year-old stage Seventh decade stage 26-year-old stage 29-year-old stage Sixth decade stage

Normal Cystic fibrosis

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Neuron

Prefrontal cortex

66-year-old stage 79-year-old stage 57-year-old stage 62-year-old stage 80 year-old and over stage 89-year-old stage 67-year-old stage 71-year-old stage 68-year-old stage 61-year-old stage 72-year-old stage 73-year-old stage 87-year-old stage 81-year-old stage

Normal Alzheimer disease

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Osteoblast Muscle precursor cell Schwann cell Peridermal cell Ectodermal cell Neural stem cell Pituitary gland cell Epithelial cell of thyroid gland Neural crest cell Neural progenitor cell Progenitor cell Immature innate lymphoid cell Embryonic blood vessel endothelial progenitor cell Erythroid progenitor cell, mammalian Mesenchymal cell Neuroplacodal cell Melanocyte

Pharyngeal arch system

Carnegie stage 14 Carnegie stage 12 Carnegie stage 13 Carnegie stage 17 Carnegie stage 20 Carnegie stage 16

Normal

Female Male

10x multiome

Nucleus

Homo sapiens

Naive thymus-derived cd4-positive, alpha-beta t cell Effector cd8-positive, alpha-beta t cell Naive thymus-derived cd8-positive, alpha-beta t cell Central memory cd4-positive, alpha-beta t cell Effector memory cd8-positive, alpha-beta t cell Activated cd4-positive, alpha-beta t cell Regulatory t cell T cell

Blood

Fourth decade stage Fifth decade stage Seventh decade stage Sixth decade stage

Normal Covid-19

Female Male

10x 5' v2 10x 5' v1

Cell

Homo sapiens

Type i nk t cell Activated cd8-positive, alpha-beta t cell Naive b cell Classical monocyte Cd4-positive, alpha-beta memory t cell Non-classical monocyte Macrophage Naive thymus-derived cd4-positive, alpha-beta t cell Mucosal invariant t cell Cd16-negative, cd56-bright natural killer cell, human Cd8-positive, alpha-beta memory t cell Conventional dendritic cell Naive thymus-derived cd8-positive, alpha-beta t cell Effector memory cd8-positive, alpha-beta t cell Hematopoietic precursor cell Intermediate monocyte Activated cd4-positive, alpha-beta t cell Plasma cell Regulatory t cell Memory b cell Plasmacytoid dendritic cell Effector memory cd8-positive, alpha-beta t cell, terminally differentiated Gamma-delta t cell Cd16-positive, cd56-dim natural killer cell, human

Blood

66-year-old stage 50-year-old stage 52-year-old stage 22-year-old stage 33-year-old stage 37-year-old stage 28-year-old stage 36-year-old stage 31-year-old stage 34-year-old stage 42-year-old stage 55-year-old stage

Common variable immunodeficiency Normal

Female Male

10x 5' v1

Cell

Homo sapiens

Myofibroblast cell Muscle cell Fibroblastic reticular cell Mesothelial cell Mesodermal cell Immature pericyte Vascular associated smooth muscle cell Fibroblast Angiogenic pericyte Mesenchymal cell Smooth muscle cell Gastrointestinal tract (lamina propria) macrophage

Body of stomach Ileum Mesenteric lymph node Small intestine Esophagus Pyloric antrum Duodenum Colon Intestine

12th week post-fertilization stage 21st week post-fertilization stage 19th week post-fertilization stage 17th week post-fertilization stage 2-month-old stage 15th week post-fertilization stage 16th week post-fertilization stage 18th week post-fertilization stage Newborn stage (0-28 days)

Normal

Female Male

10x 5' v2 10x 3' v2

Cell

Homo sapiens

Myofibroblast cell Mesenchymal stem cell Classical monocyte Cd4-positive, alpha-beta t cell Muscle cell Platelet Non-classical monocyte Leukocyte Macrophage Mast cell Neutrophil Monocyte Myeloid dendritic cell Fibroblast Hematopoietic precursor cell Pericyte Endothelial cell Intermediate monocyte B cell Cd8-positive, alpha-beta t cell Activated cd4-positive, alpha-beta t cell Plasma cell Erythrocyte Mature nk t cell T cell Mesenchymal stem cell of adipose tissue Smooth muscle cell Natural killer cell

Brown adipose tissue Adipose tissue Subcutaneous adipose tissue

60-year-old stage 45-year-old stage 33-year-old stage 59-year-old stage 56-year-old stage 61-year-old stage

Normal

Female Male

Smart-seq2 10x 3' v3

Cell

Homo sapiens

Activated cd8-positive, alpha-beta t cell Igg plasma cell Follicular b cell Innate lymphoid cell Cd4-positive, alpha-beta t cell Platelet Lymphocyte Macrophage Naive thymus-derived cd4-positive, alpha-beta t cell Monocyte Cd8-alpha alpha positive, gamma-delta intraepithelial t cell Plasmablast Conventional dendritic cell Hematopoietic stem cell B cell Cd8-positive, alpha-beta t cell Cd4-positive, cd25-positive, alpha-beta regulatory t cell Dendritic cell T cell Plasmacytoid dendritic cell Igm plasma cell T follicular helper cell Natural killer cell

Spleen

Fifth decade stage Third decade stage Sixth decade stage

Normal

Female Male

10x 3' v2

Cell

Mus musculus

Glutamatergic neuron Gabaergic neuron

Primary motor cortex

19-week-old stage 12-week-old stage 13-week-old stage 29-week-old stage 17-week-old stage 16-week-old stage 7-week-old stage 10-week-old stage 21-week-old stage 23-week-old stage 18-week-old stage 8-month-old stage 5-week-old stage 26-week-old stage 6-week-old stage 20-week-old stage 25-week-old stage Prime adult stage 14-week-old stage 15-week-old stage 9-week-old stage 8-week-old stage 11-week-old stage

Normal

Female Male

Patch-seq 10x 3' v2

Cell

Homo sapiens

Myoepithelial cell Inflammatory macrophage Igg plasma cell Cd4-positive, alpha-beta t cell Cd8-positive, alpha-beta regulatory t cell Ionocyte Iga plasma cell Effector cd8-positive, alpha-beta t cell Alternatively activated macrophage Duct epithelial cell Acinar cell of salivary gland Cd8-positive, alpha-beta cytotoxic t cell Fibroblast Endothelial cell B cell Pro-t cell Dendritic cell Mature nk t cell Smooth muscle cell

Labial gland

50-year-old stage 48-year-old stage 45-year-old stage 65-year-old stage 40-year-old stage 75-year-old stage 59-year-old stage 54-year-old stage 47-year-old stage 56-year-old stage 58-year-old stage 61-year-old stage 51-year-old stage 35-year-old stage 53-year-old stage 39-year-old stage 43-year-old stage 38-year-old stage 55-year-old stage

Normal Sjogren syndrome

Female Male

10x 3' v3 10x 3' v2

Cell

Mus musculus

Classical monocyte Astrocyte Oligodendrocyte precursor cell Macrophage Naive thymus-derived cd4-positive, alpha-beta t cell Stromal cell Neoplastic cell Endothelial cell of high endothelial venule Memory t cell Microglial cell Conventional dendritic cell Fibroblast Naive thymus-derived cd8-positive, alpha-beta t cell Effector memory cd8-positive, alpha-beta t cell Pericyte B cell Effector cd4-positive, alpha-beta t cell Cd4-positive, cd25-positive, alpha-beta regulatory t cell Plasma cell Mature nk t cell T cell Plasmacytoid dendritic cell Smooth muscle cell Neuron Natural killer cell Choroid plexus epithelial cell Gamma-delta t cell Exhausted t cell Mature neutrophil

Brain

2-month-old stage

Glioblastoma

Female Male

10x 3' v3

Cell