Homo sapiens

Endothelial cell of venule Endothelial cell of arteriole Endothelial cell of artery Fenestrated endothelial cell Vein endothelial cell

Chorioretinal region

69-year-old stage 21-year-old stage 34-year-old stage 65-year-old stage 43-year-old stage 71-year-old stage 53-year-old stage 68-year-old stage 30-year-old stage 17-year-old stage 82-year-old stage 50-year-old stage 72-year-old stage 81-year-old stage 16-year-old stage 58-year-old stage 25-year-old stage 90 year-old and over stage 32-year-old stage 77-year-old stage 64-year-old stage 62-year-old stage 86-year-old stage 46-year-old stage 60-year-old stage Newborn stage (0-28 days) 63-year-old stage 47-year-old stage 11-year-old stage 27-year-old stage 10-year-old stage

Normal

Female Male

10x 5' v2 10x 3' v3

Nucleus

Homo sapiens

Type b pancreatic cell

Islet of langerhans

66-year-old stage 37-year-old stage 21-year-old stage 34-year-old stage 42-year-old stage 26-year-old stage 53-year-old stage 61-year-old stage 52-year-old stage 54-year-old stage 48-year-old stage 30-year-old stage 38-year-old stage 55-year-old stage 50-year-old stage 51-year-old stage 57-year-old stage 49-year-old stage 35-year-old stage 58-year-old stage 59-year-old stage 25-year-old stage 32-year-old stage 45-year-old stage 62-year-old stage 60-year-old stage 63-year-old stage 40-year-old stage

Prediabetes syndrome Normal Type 2 diabetes mellitus

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Oligodendrocyte precursor cell Direct pathway medium spiny neuron Endothelial cell Oligodendrocyte Inhibitory interneuron Microglial cell Mural cell Indirect pathway medium spiny neuron Astrocyte Medium spiny neuron

Caudate nucleus Putamen

37-year-old stage 42-year-old stage 54-year-old stage 39-year-old stage 55-year-old stage 23-year-old stage 35-year-old stage 41-year-old stage 60-year-old stage 40-year-old stage

Normal Opiate dependence

Female Male

10x 3' v3

Nucleus

Homo sapiens

Stem cell Paneth cell Epithelial cell Enteroendocrine cell Goblet cell Tuft cell Enterocyte

Ascending colon Colonic epithelium Lamina propria of mucosa of colon Colon Mucosa of transverse colon Cecum mucosa Caecum epithelium Mucosa of sigmoid colon Descending colon Sigmoid colon

Sixth decade stage Fifth decade stage Third decade stage Seventh decade stage Adult stage Fourth decade stage Eighth decade stage

Normal Crohn disease

Female Male

10x 3' v1 10x 3' v3 10x 3' v2

Cell

Homo sapiens

T cell Neutrophil Natural killer cell Erythrocyte Gamma-delta t cell Mature nk t cell Platelet Plasmacytoid dendritic cell Cd8-positive, alpha-beta memory t cell Naive thymus-derived cd8-positive, alpha-beta t cell Memory b cell Cd16-positive, cd56-dim natural killer cell, human Regulatory t cell Plasmablast Hematopoietic stem cell Plasma cell Cd14-positive monocyte Cd14-low, cd16-positive monocyte Cd4-positive, alpha-beta memory t cell B cell Naive thymus-derived cd4-positive, alpha-beta t cell Mucosal invariant t cell Immature b cell Naive b cell Conventional dendritic cell Cd16-negative, cd56-bright natural killer cell, human

Blood

Covid-19

10x 5' v1

Cell

Homo sapiens

T cell Neutrophil Podocyte Renal principal cell Endothelial cell of lymphatic vessel Parietal epithelial cell Kidney interstitial alternatively activated macrophage Renal beta-intercalated cell Renal interstitial pericyte Mast cell Epithelial cell of early distal convoluted tubule Endothelial cell of arteriole Peritubular capillary endothelial cell Kidney outer medulla collecting duct intercalated cell Epithelial cell of proximal tubule Plasmacytoid dendritic cell Vasa recta descending limb cell Myeloid dendritic cell Lymphocyte Kidney connecting tubule epithelial cell Kidney connecting tubule principal cell Kidney loop of henle thick ascending limb epithelial cell Vasa recta ascending limb cell Epithelial cell of proximal tubule segment 3 Macula densa epithelial cell Plasma cell Mesangial cell Kidney collecting duct alpha-intercalated cell B cell Vascular associated smooth muscle cell Kidney loop of henle thin ascending limb epithelial cell Glomerular capillary endothelial cell Kidney proximal convoluted tubule epithelial cell Fibroblast Non-classical monocyte

Cortex of kidney

69-year-old stage 43-year-old stage 71-year-old stage 53-year-old stage 68-year-old stage 50-year-old stage 57-year-old stage 72-year-old stage 74-year-old stage 58-year-old stage 59-year-old stage 67-year-old stage 46-year-old stage 60-year-old stage 79-year-old stage

Normal

Female Male

10x multiome 10x 5' v1 10x 3' v3

Cell Nucleus

Drosophila melanogaster

Indirect flight muscle cell Subperineurial glial cell Eo sensory organ accessory cell Hemocyte Enteroendocrine cell Follicle cell Germline cell Muscle cell Escort cell Cell body glial cell

Day 5 of adulthood

Normal

Mixed sex Female Male

10x 3' v3

Homo sapiens

Intestine goblet cell Best4+ enterocyte Paneth cell Enteroendocrine cell Intestinal crypt stem cell Tuft cell of small intestine Enterocyte Transit amplifying cell Colonocyte

Ascending colon Colonic mucosa Colonic epithelium Rectosigmoid junction Caecum Lamina propria of mucosa of colon Colon Epithelium of rectum Vermiform appendix Rectum Transverse colon Descending colon Sigmoid colon

66-year-old stage Pediatric stage Sixth decade stage 85-year-old stage 2-year-old stage 52-year-old stage 54-year-old stage 30-year-old stage 44-year-old stage 29-year-old stage Fifth decade stage 55-year-old stage 84-year-old stage 50-year-old stage 51-year-old stage Third decade stage 81-year-old stage 74-year-old stage 23-year-old stage 35-year-old stage Seventh decade stage Adult stage 67-year-old stage 77-year-old stage 33-year-old stage 86-year-old stage 60-year-old stage 31-year-old stage Eighth decade stage 5-year-old stage Juvenile stage (5-14 yo)

Inflammatory bowel disease Colorectal cancer Ulcerative colitis Normal

Female Male

10x 5' v2 10x 5' transcription profiling 10x 5' v1 10x 3' v3 10x 3' v2

Cell

Mus musculus

Neutrophil Muscle cell Endothelial cell of lymphatic vessel Erythrocyte Non-myelinating schwann cell Tendon cell Endothelial cell of artery Capillary endothelial cell Smooth muscle cell Adipocyte Macrophage Type iib muscle cell Vein endothelial cell Type ii muscle cell B cell Pericyte Skeletal muscle satellite stem cell Type i muscle cell Monocyte Type iia muscle cell Fibroblast Myelinating schwann cell Extrafusal muscle fiber

Hindlimb muscle

19-month-old stage 3-month-old stage

Normal

Male

10x 3' v2

Cell Nucleus

Homo sapiens

Nasal mucosa goblet cell Endocardial cell Club cell Respiratory tract goblet cell Dendritic cell, human Stromal cell Natural killer cell Bronchial goblet cell Cytotoxic t cell Secretory cell Mucus secreting cell of bronchus submucosal gland Mast cell Cd8-positive, alpha-beta t cell Pulmonary neuroendocrine cell Cd4-positive helper t cell Basal cell Ionocyte Macrophage Innate lymphoid cell Fibroblast of lung Plasma cell Respiratory tract suprabasal cell Alveolar adventitial fibroblast B cell Pericyte Respiratory tract multiciliated cell Mature t cell Alveolar type 1 fibroblast cell Epithelial cell of lung Monocyte Non-classical monocyte

Respiratory tube Carina of trachea

26-year-old stage Sixth decade stage 30-year-old stage 29-year-old stage Fifth decade stage 24-year-old stage 35-year-old stage Seventh decade stage Adult stage 33-year-old stage 31-year-old stage 27-year-old stage

Cystic fibrosis Normal

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Neuron

Prefrontal cortex

66-year-old stage 89-year-old stage 87-year-old stage 71-year-old stage 61-year-old stage 68-year-old stage 57-year-old stage 72-year-old stage 81-year-old stage 80 year-old and over stage 67-year-old stage 62-year-old stage 79-year-old stage 73-year-old stage

Normal Alzheimer disease

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Osteoblast Neural stem cell Erythroid progenitor cell, mammalian Peridermal cell Ectodermal cell Schwann cell Melanocyte Neuroplacodal cell Neural crest cell Muscle precursor cell Epithelial cell of thyroid gland Immature innate lymphoid cell Embryonic blood vessel endothelial progenitor cell Pituitary gland cell Mesenchymal cell Progenitor cell Neural progenitor cell

Pharyngeal arch system

Carnegie stage 14 Carnegie stage 13 Carnegie stage 20 Carnegie stage 17 Carnegie stage 12 Carnegie stage 16

Normal

Female Male

10x multiome

Nucleus