Homo sapiens

Myofibroblast cell Capillary endothelial cell Endothelial cell of vascular tree Vein endothelial cell Vascular associated smooth muscle cell Fibroblast Pericyte Endothelial cell Cycling stromal cell Endothelial cell of artery

Breast

80-year-old stage 85-year-old stage 82-year-old stage 66-year-old stage 70-year-old stage 32-year-old stage 50-year-old stage 57-year-old stage 62-year-old stage Prime adult stage 46-year-old stage 52-year-old stage 60-year-old stage 60-79 year-old stage 80 year-old and over stage 64-year-old stage 45-year-old stage 25-year-old stage 65-year-old stage 67-year-old stage Middle aged stage Eighth decade stage 71-year-old stage Adult stage Ninth decade stage 36-year-old stage 63-year-old stage 59-year-old stage 54-year-old stage Fifth decade stage 47-year-old stage 58-year-old stage 61-year-old stage 49-year-old stage 42-year-old stage 35-year-old stage 73-year-old stage 30-year-old stage Seventh decade stage 88-year-old stage 84-year-old stage 69-year-old stage 43-year-old stage Late adult stage 29-year-old stage 38-year-old stage 41-year-old stage 55-year-old stage 83-year-old stage Sixth decade stage

Breast cancer Invasive ductal breast carcinoma Breast mucinous carcinoma Her2 positive breast carcinoma Triple-negative breast carcinoma Invasive lobular breast carcinoma Estrogen-receptor positive breast cancer Metaplastic breast carcinoma Invasive tubular breast carcinoma Breast carcinoma Breast apocrine carcinoma

Female Male

10x 5' v2 10x 5' v1 10x 3' v3 10x 5' transcription profiling 10x 3' v2

Cell

Mus musculus

Spiral ganglion neuron Parasympathetic neuron Sensory neuron of dorsal root ganglion Peripheral nervous system neuron Enteric neuron Sympathetic neuron

Embryo

Theiler stage 23 Theiler stage 24 Theiler stage 21 Theiler stage 13 Theiler stage 25 Theiler stage 17 Theiler stage 16 Theiler stage 26 Theiler stage 12 Theiler stage 18 Theiler stage 20 Theiler stage 19 Theiler stage 27 Theiler stage 14 Theiler stage 15 Theiler stage 22

Normal

Female Male

Sci-rna-seq3

Nucleus

Mus musculus

Glutamatergic neuron Astrocyte Oligodendrocyte precursor cell Oligodendrocyte Gabaergic neuron Neural progenitor cell Leptomeningeal cell Microglial cell Pericyte Endothelial cell

Orbitofrontal cortex Anterior olfactory nucleus Caudate-putamen Dentate gyrus of hippocampal formation Primary somatosensory cortex Olfactory cortex Lateral septal complex Primary auditory cortex Pallidum Cerebral cortex Neocortex Primary motor cortex Hippocampal field Piriform cortex Nucleus accumbens Secondary somatosensory cortex Prefrontal cortex

8-week-old stage

Normal

Male

Snmc-seq2

Nucleus

Mus musculus

Glutamatergic neuron Astrocyte Oligodendrocyte precursor cell Oligodendrocyte Gabaergic neuron Neural progenitor cell Leptomeningeal cell Microglial cell Pericyte Endothelial cell

Orbitofrontal cortex Anterior olfactory nucleus Caudate-putamen Dentate gyrus of hippocampal formation Primary somatosensory cortex Olfactory cortex Lateral septal complex Primary auditory cortex Pallidum Cerebral cortex Neocortex Primary motor cortex Hippocampal field Piriform cortex Nucleus accumbens Secondary somatosensory cortex Prefrontal cortex

8-week-old stage

Normal

Male

Snmc-seq2

Nucleus

Homo sapiens

Osteoblast Myofibroblast cell Pro-b cell Endosteal cell Common myeloid progenitor Myeloid lineage restricted progenitor cell Muscle precursor cell Promonocyte Schwann cell Naive b cell Osteoclast Cd4-positive, alpha-beta t cell Muscle cell Endothelial cell of sinusoid Macrophage Granulocyte monocyte progenitor cell Promyelocyte Mast cell Endothelial tip cell Megakaryocyte-erythroid progenitor cell Cd16-negative, cd56-bright natural killer cell, human Macrophage dendritic cell progenitor Fraction a pre-pro b cell Adipocyte Neutrophil Megakaryocyte Cd14-positive monocyte Immature b cell Lymphoid lineage restricted progenitor cell Progenitor cell Preosteoblast Immature innate lymphoid cell Primitive red blood cell Immature natural killer cell Early lymphoid progenitor Fibroblast Endothelial cell Cd8-positive, alpha-beta t cell Dendritic cell Erythrocyte Regulatory t cell Mature nk t cell Plasmacytoid dendritic cell Common dendritic progenitor Myelocyte Precursor b cell Precursor cell Basophil Eosinophil Natural killer cell Chondrocyte Hematopoietic multipotent progenitor cell Basophil mast progenitor cell

Bone marrow

13th week post-fertilization stage 19th week post-fertilization stage 17th week post-fertilization stage 15th week post-fertilization stage 14th week post-fertilization stage 16th week post-fertilization stage

Normal

Female Male

10x 5' v1 10x 3' v2

Cell

Homo sapiens

Mature t cell

Normal Myasthenia gravis Multiple sclerosis Systemic lupus erythematosus

10x 5' v2

Mus musculus

Myotendinous junction nucleus Schwann cell Lymphocyte Macrophage Skeletal muscle satellite stem cell Perineurial cell Adipocyte Intermediate muscle cell Tendon cell Type iia muscle cell Fibro/adipogenic progenitor cell Blood vessel endothelial cell Type iib muscle cell Pericyte Type iix muscle cell Smooth muscle cell Neuromuscular junction nucleus Microvascular endothelial cell

Gastrocnemius Skeletal muscle tissue of tibialis anterior

Prime adult stage

Lesion of sciatic nerve Normal Toxin-mediated infectious botulism Neuromuscular junction disease

Male

10x 3' v3

Nucleus

Homo sapiens

Osteoblast Articular chondrocyte Tendon cell Fibroblast Pericyte Mesenchymal cell Connective tissue cell Fibroblast of dermis Hypertrophic chondrocyte Muscle fibroblast Chondroblast Smooth muscle cell Chondrocyte

Hindlimb Forelimb

9th week post-fertilization stage 10th week post-fertilization stage Carnegie stage 19 Carnegie stage 23 Carnegie stage 15 Carnegie stage 17 Carnegie stage 18 Carnegie stage 16

Normal

Female Male

10x 5' v1 10x 3' v2

Cell

Homo sapiens

Glutamatergic neuron Vascular leptomeningeal cell Astrocyte Oligodendrocyte precursor cell Oligodendrocyte Gabaergic neuron Perivascular cell Microglial cell Ependymal cell Pericyte Endothelial cell

Hippocampal formation Anterior cingulate cortex Dorsolateral prefrontal cortex Caudate nucleus

62-year-old stage 14-year-old stage 6-year-old stage Infant stage 20-year-old stage 61-year-old stage 39-year-old stage 4-year-old stage

Normal

Female Male

10x multiome

Nucleus

Mus musculus

Glutamatergic neuron Vascular leptomeningeal cell Oligodendrocyte Gabaergic neuron Lymphocyte Medium spiny neuron Forebrain neuroblast Smooth muscle cell of the brain vasculature Microglial cell Brain microvascular endothelial cell Choroid plexus epithelial cell

Normal Prion disease

10x 3' transcription profiling

Drosophila melanogaster

Adult somatic muscle cell of head Adult brain perineurial glial cell Hemocyte

Head

Day 5 of adulthood

Normal

Female Male Mixed sex

10x 3' v3

Homo sapiens

Supporting cell Leukocyte Endothelial cell of uterus Glandular secretory epithelial cell Epithelial cell Stromal cell of ovary Fibroblast Ciliated cell Uterine smooth muscle cell Myeloid cell

Endometrium

Young adult stage 37-year-old stage 26-year-old stage Third decade stage 29-year-old stage

Normal

Female

10x 3' v3 10x 3' v2

Cell