Mus musculus

T cell Neutrophil Podocyte Natural killer cell Renal beta-intercalated cell Kidney collecting duct epithelial cell Glomerular endothelial cell Endothelial cell Kidney loop of henle thin descending limb epithelial cell Kidney loop of henle cortical thick ascending limb epithelial cell Kidney glomerular epithelial cell Epithelial cell of proximal tubule Vasa recta descending limb cell Kidney cortex tubule cell Renal alpha-intercalated cell Kidney afferent arteriole endothelial cell Macrophage Kidney loop of henle medullary thick ascending limb epithelial cell Kidney distal convoluted tubule epithelial cell Kidney collecting duct principal cell Kidney connecting tubule epithelial cell Kidney loop of henle epithelial cell Macula densa epithelial cell Mesangial cell B cell Pericyte Kidney loop of henle thin ascending limb epithelial cell Fibroblast Dendritic cell Kidney efferent arteriole endothelial cell

Cortex of kidney Inner medulla of kidney Kidney Outer medulla of kidney Renal glomerulus Renal medulla

Postnatal stage 12-week-old stage Prime adult stage Mature stage 2-month-old stage 8-week-old stage

Normal

Male

Dronc-seq 10x 3' transcription profiling 10x 3' v3 Drop-seq 10x 3' v2

Nucleus Cell

Homo sapiens

T cell Natural killer cell Oligodendrocyte precursor cell Oligodendrocyte Schwann cell Melanocyte Macrophage Microglial cell Pigmented epithelial cell B cell Pericyte Vascular associated smooth muscle cell Astrocyte Fibroblast Myelinating schwann cell

Normal

10x 3' v1

Homo sapiens

T cell Natural killer cell Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Schwann cell Melanocyte Macrophage Microglial cell Pigmented epithelial cell B cell Pericyte Vascular associated smooth muscle cell Astrocyte Fibroblast Myelinating schwann cell

Cranial nerve ii Macula lutea Optic disc Peripheral region of retina Pigmented layer of retina Sclera

69-year-old stage 65-year-old stage 71-year-old stage 53-year-old stage 30-year-old stage 50-year-old stage 72-year-old stage 74-year-old stage 67-year-old stage 77-year-old stage 33-year-old stage 47-year-old stage 76-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Oligodendrocyte precursor cell Oligodendrocyte Vascular leptomeningeal cell Pvalb chandelier gabaergic interneuron Lamp5 gabaergic interneuron Microglial cell Vip gabaergic interneuron L2/3-6 intratelencephalic projecting glutamatergic neuron L5 extratelencephalic projecting glutamatergic cortical neuron L6b glutamatergic cortical neuron Pvalb gabaergic interneuron Near-projecting glutamatergic cortical neuron Cerebral cortex endothelial cell Caudal ganglionic eminence derived interneuron Sncg gabaergic interneuron Astrocyte of the cerebral cortex Sst gabaergic interneuron Corticothalamic-projecting glutamatergic cortical neuron

Primary auditory cortex

42-year-old stage 43-year-old stage 29-year-old stage 50-year-old stage 60-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Glioblast Oligodendrocyte

Basal forebrain Brain Caudate-putamen Cerebellar peduncular complex Cerebellum Cerebral subcortex Cortex Diencephalon Dorsal plus ventral thalamus Entorhinal cortex Forebrain Frontal cortex Hindbrain Hippocampal formation Hypothalamus Lower layers of the cortex Medulla oblongata Metencephalon Midbrain Midbrain tectum Occipital cortex Pons Striatum Telencephalon Upper layers of the cortex

13th week post-fertilization stage 14th week post-fertilization stage 15th week post-fertilization stage 12th week post-fertilization stage Carnegie stage 20 9th week post-fertilization stage 10th week post-fertilization stage Carnegie stage 22 Carnegie stage 16 Carnegie stage 15 Carnegie stage 18 11th week post-fertilization stage

Normal

10x 3' v3 10x 3' v2

Cell

Danio rerio

Fast muscle cell Slow muscle myoblast Slow muscle cell Fast muscle myoblast

Fast muscle tissue Multicellular anatomical structure Pharyngeal arch Slow muscle tissue

Pharyngula:prim-15 Hatching:long-pec Larval:protruding-mouth Pharyngula:prim-25 Segmentation:26+ somites Segmentation:14-19 somites Hatching:pec-fin Segmentation:20-25 somites Pharyngula:high-pec Pharyngula:prim-5

Normal

Sci-rna-seq3

Nucleus

Homo sapiens

Cerebellar granule cell Neuron Unipolar brush cell

Brodmann (1909) area 19 Brodmann (1909) area 38 Anterior nuclear group Basolateral amygdaloid nuclear complex Bed nucleus of stria terminalis Body of caudate nucleus Central amygdaloid nucleus Cerebellar nuclear complex Cerebellar vermis Cerebrocerebellum Corticomedial nuclear complex Dentate gyrus of hippocampal formation Dorsal tegmental nucleus Epithalamus Globus pallidus Gray matter of midbrain Hippocampal field Hypothalamus Inferior olivary complex Intralaminar nuclear group Lateral entorhinal cortex Lateral geniculate body Lateral nuclear group of thalamus Lateral posterior nucleus of thalamus Mammillary body Medial dorsal nucleus of thalamus Medial entorhinal cortex Medial geniculate body Medial zone of hypothalamus Midbrain nucleus Midbrain tectum Middle temporal gyrus Nucleus of medulla oblongata Parabrachial nucleus Pontine nuclear group Pontine reticular formation Pontine tegmentum Posterior parahippocampal gyrus Pretectal region Primary motor cortex Pulvinar nucleus Red nucleus Retrosplenial region Septal nuclear complex Spinal cord Substantia innominata Substantia nigra Temporal fusiform gyrus

42-year-old stage 29-year-old stage 50-year-old stage 60-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

T cell Effector cd8-positive, alpha-beta t cell Erythrocyte Follicular dendritic cell Mature nk t cell Cd8-positive, alpha-beta t cell Exhausted t cell Plasmacytoid dendritic cell Cd4-positive, alpha-beta cytotoxic t cell Naive thymus-derived cd8-positive, alpha-beta t cell Regulatory t cell Myeloid cell Plasma cell Cd4-positive, alpha-beta t cell Malignant cell T follicular helper cell B cell Naive thymus-derived cd4-positive, alpha-beta t cell

Lymph node

Follicular lymphoma Normal

10x 5' v1

Cell

Macaca mulatta

Astrocyte

Brodmann (1909) area 19 Amygdala Anterior cingulate cortex Cerebellar vermis Cerebrocerebellum Corpus callosum Dorsolateral prefrontal cortex Entorhinal cortex Head of caudate nucleus Hippocampal formation Inferior parietal cortex Inferior temporal gyrus Lateral geniculate body Medial dorsal nucleus of thalamus Medulla oblongata Midbrain Nucleus accumbens Perirhinal cortex Pons Prefrontal cortex Primary auditory cortex Primary motor cortex Primary somatosensory cortex Primary visual cortex Superior parietal cortex Superior temporal sulcus Ventral lateral nucleus of thalamus

Juvenile stage Prime adult stage

Normal

Female Male

Sci-rna-seq3

Nucleus

Homo sapiens

Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Lymphocyte Macrophage Microglial cell Neoplastic cell B cell Pericyte Monocyte Vascular associated smooth muscle cell Astrocyte Fibroblast

Right temporal lobe

73-year-old stage

Glioblastoma

Male

10x 3' v3

Cell

Homo sapiens

Oligodendrocyte precursor cell Oligodendrocyte Vascular leptomeningeal cell Pvalb chandelier gabaergic interneuron Lamp5 gabaergic interneuron Microglial cell Vip gabaergic interneuron L2/3-6 intratelencephalic projecting glutamatergic neuron L5 extratelencephalic projecting glutamatergic cortical neuron L6b glutamatergic cortical neuron Pvalb gabaergic interneuron Near-projecting glutamatergic cortical neuron Cerebral cortex endothelial cell Caudal ganglionic eminence derived interneuron Sncg gabaergic interneuron Astrocyte of the cerebral cortex Sst gabaergic interneuron Corticothalamic-projecting glutamatergic cortical neuron

Anterior cingulate cortex

42-year-old stage 43-year-old stage 29-year-old stage 50-year-old stage 60-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Hepatocyte Natural killer cell Pro-t cell Neutrophilic myeloblast Endothelial cell Kupffer cell Pro-b cell Mast cell Multi fate stem cell Stem cell Erythroid lineage cell Plasmacytoid dendritic cell Precursor b cell Common dendritic progenitor Macrophage Innate lymphoid cell Common myeloid progenitor Hematopoietic multipotent progenitor cell Megakaryocyte B cell Granulocyte monocyte progenitor cell Common lymphoid progenitor Megakaryocyte-erythroid progenitor cell Fraction a pre-pro b cell Monocyte Conventional dendritic cell Fibroblast Mononuclear phagocyte

Metanephros Liver Zone of skin Yolk sac

Carnegie stage 14 13th week post-fertilization stage 14th week post-fertilization stage 15th week post-fertilization stage 17th week post-fertilization stage 12th week post-fertilization stage 9th week post-fertilization stage Carnegie stage 23 10th week post-fertilization stage 18th week post-fertilization stage Carnegie stage 22 11th week post-fertilization stage

Normal

Female Male

10x genomics v2