Mus musculus

Endothelial cell of hepatic sinusoid Macrophage Cholangiocyte Neutrophil Periportal region hepatocyte Hepatic portal fibroblast B cell Hepatic stellate cell T cell Liver dendritic cell Centrilobular region hepatocyte

Normal

10x 3' v3

Homo sapiens

Ciliated epithelial cell Endothelial cell of lymphatic vessel Lymphocyte Macrophage Stromal cell Mast cell Perivascular cell Fallopian tube secretory epithelial cell Peg cell Endothelial cell Plasma cell Smooth muscle cell

Fimbria of fallopian tube Ampulla of fallopian tube

70-year-old stage 32-year-old stage 62-year-old stage 44-year-old stage 48-year-old stage 65-year-old stage 40-year-old stage 37-year-old stage 47-year-old stage 61-year-old stage 42-year-old stage 72-year-old stage 43-year-old stage 55-year-old stage

Normal

Female

10x 3' v3 Drop-seq

Cell

Macaca mulatta

L2/3 intratelencephalic projecting glutamatergic neuron Inhibitory interneuron Vascular leptomeningeal cell Astrocyte Oligodendrocyte precursor cell Oligodendrocyte Macrophage L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex Erythroid lineage cell L6 corticothalamic-projecting glutamatergic cortical neuron L5/6 near-projecting glutamatergic neuron of the primary motor cortex Sst gabaergic interneuron Microglial cell Lamp5 gabaergic interneuron L6b glutamatergic cortical neuron Pericyte Endothelial cell B cell T cell Smooth muscle cell L5 extratelencephalic projecting glutamatergic cortical neuron Vip gabaergic interneuron Pvalb gabaergic interneuron Pvalb chandelier gabaergic interneuron Myeloid cell

Dorsolateral prefrontal cortex

Prime adult stage

Normal

Female Male

10x 3' v3

Nucleus

Mus musculus

Innate lymphoid cell Cd4-positive, alpha-beta t cell Macrophage Stromal cell Mast cell Neutrophil Monocyte Conventional dendritic cell Endothelial cell B cell Cd8-positive, alpha-beta t cell Plasma cell Plasmacytoid dendritic cell Neuron Eosinophil Natural killer cell

Meningeal dura mater Dura mater Coronal suture Subdural space Brain Bone marrow Brain meninx

Theiler stage 23 Theiler stage 25 3-month-old stage 20-month-old stage and over 16-month-old stage 2-month-old stage 9-week-old stage

Normal

Female Male

10x 5' v1 10x 3' v3 10x 3' v2

Cell

Homo sapiens

Group 1 innate lymphoid cell Innate lymphoid cell Cd16-negative, cd56-bright natural killer cell, human Immature innate lymphoid cell Group 3 innate lymphoid cell Cd16-positive, cd56-dim natural killer cell, human

Blood Mesenteric lymph node Spleen Epithelial lining fluid Lung Jejunum lamina propria Inguinal lymph node Bone marrow Jejunal epithelium Thoracic lymph node

Fourth decade stage 48-year-old stage 64-year-old stage 25-year-old stage 33-year-old stage 67-year-old stage Eighth decade stage 75-year-old stage 27-year-old stage 23-year-old stage Fifth decade stage 20-year-old stage 56-year-old stage 68-year-old stage 73-year-old stage Third decade stage Sixth decade stage

Normal

Female Male

10x 5' v2 10x 3' v3

Cell

Homo sapiens

Cardiac muscle cell

Normal

Spatial transcriptomics

Homo sapiens

Cerebral cortex neuron Pyramidal neuron Astrocyte Oligodendrocyte precursor cell Oligodendrocyte Interneuron Microglial cell Endothelial cell

Hippocampal formation

60-year-old stage 44-year-old stage 37-year-old stage 24-year-old stage 26-year-old stage

Epilepsy

Female Male

10x 3' v3 10x 3' v2

Nucleus

Homo sapiens

Caudal ganglionic eminence derived interneuron Sncg gabaergic interneuron Lamp5 gabaergic interneuron Vip gabaergic interneuron

Middle temporal gyrus Primary somatosensory cortex Anterior cingulate cortex Primary auditory cortex Dorsolateral prefrontal cortex Primary motor cortex Primary visual cortex Angular gyrus

50-year-old stage 60-year-old stage 42-year-old stage 43-year-old stage 29-year-old stage Sixth decade stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Cd8-positive, alpha-beta thymocyte Classical monocyte Innate lymphoid cell Cd4-positive, alpha-beta t cell Non-classical monocyte Macrophage Naive thymus-derived cd4-positive, alpha-beta t cell Stromal cell Mast cell Cd4-positive, alpha-beta thymocyte Neutrophil Monocyte Myeloid dendritic cell Hematopoietic precursor cell Endothelial cell Intermediate monocyte B cell Cd8-positive, alpha-beta t cell Plasma cell Erythrocyte Regulatory t cell Mature nk t cell T cell Plasmacytoid dendritic cell Natural killer cell

Mesenteric lymph node Inguinal lymph node Lymph node

60-year-old stage 45-year-old stage 59-year-old stage 56-year-old stage 61-year-old stage 69-year-old stage

Normal

Female Male

Smart-seq2 10x 5' v2 10x 3' v3

Cell

Homo sapiens

Pro-b cell Mature b cell Granulocyte monocyte progenitor cell Megakaryocyte-erythroid progenitor cell Monocyte Common lymphoid progenitor Immature b cell Conventional dendritic cell Hematopoietic stem cell Plasma cell Mature nk t cell T cell Plasmacytoid dendritic cell Common dendritic progenitor Precursor b cell Early pro-b cell Hematopoietic multipotent progenitor cell

Blood

6-month-old stage 3-month-old stage 4-month-old stage 11-month-old stage 10-month-old stage 1-month-old stage 8-month-old stage 2-month-old stage 7-month-old stage 9-month-old stage Newborn stage (0-28 days)

B-cell acute lymphoblastic leukemia

Female Male

10x 3' v3

Cell

Homo sapiens

L2/3-6 intratelencephalic projecting glutamatergic neuron

Middle temporal gyrus

80-year-old stage 85-year-old stage 82-year-old stage 70-year-old stage 77-year-old stage 50-year-old stage 86-year-old stage 60-year-old stage 80 year-old and over stage 89-year-old stage 65-year-old stage 75-year-old stage Adult stage 78-year-old stage 68-year-old stage 72-year-old stage 88-year-old stage 84-year-old stage 69-year-old stage 43-year-old stage 29-year-old stage 87-year-old stage 81-year-old stage 83-year-old stage

Normal Dementia

Female Male

10x 3' v3 10x multiome

Nucleus

Homo sapiens

Neuron

Anterior olfactory nucleus Pretectal region Gray matter of midbrain Hypothalamus Dentate gyrus of hippocampal formation Lateral geniculate body Bed nucleus of stria terminalis Median tuberal portion Medial geniculate body Preoptic area Substantia innominata Lateral nuclear group of thalamus Dorsal tegmental nucleus Centromedian nucleus of thalamus Epithalamus Substantia nigra Central amygdaloid nucleus Globus pallidus Basolateral amygdaloid nuclear complex Parabrachial nucleus Ventral anterior nucleus of thalamus Nucleus of dorsal thalamus Anterior nuclear group Red nucleus Corticomedial nuclear complex Lateral posterior nucleus of thalamus Nucleus of medulla oblongata Cerebellar nuclear complex Midbrain nucleus Primary motor cortex Pulvinar nucleus Pontine tegmentum Subthalamic nucleus Spinal cord Inferior olivary complex Lateral amygdaloid nucleus Midbrain tectum Mammillary body Pontine reticular formation Pontine nuclear group Medial dorsal nucleus of thalamus Medial zone of hypothalamus Intralaminar nuclear group Accessory basal amygdaloid nucleus Septal nuclear complex

50-year-old stage 60-year-old stage 42-year-old stage 29-year-old stage

Normal

Female Male

10x 3' v3

Nucleus