Homo sapiens

Oligodendrocyte precursor cell Oligodendrocyte Vascular leptomeningeal cell Pvalb chandelier gabaergic interneuron Lamp5 gabaergic interneuron Microglial cell Vip gabaergic interneuron L2/3-6 intratelencephalic projecting glutamatergic neuron L5 extratelencephalic projecting glutamatergic cortical neuron L6b glutamatergic cortical neuron Pvalb gabaergic interneuron Near-projecting glutamatergic cortical neuron Cerebral cortex endothelial cell Caudal ganglionic eminence derived interneuron Sncg gabaergic interneuron Astrocyte of the cerebral cortex Sst gabaergic interneuron Corticothalamic-projecting glutamatergic cortical neuron

Primary somatosensory cortex

42-year-old stage 43-year-old stage 29-year-old stage 50-year-old stage 60-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

T cell Natural killer cell Mast cell Cd8-positive, alpha-beta t cell Leukocyte Plasmacytoid dendritic cell Macrophage Innate lymphoid cell Regulatory t cell Plasma cell Cd4-positive, alpha-beta t cell B cell Naive t cell Monocyte Conventional dendritic cell Dendritic cell

Ascending colon Caecum epithelium Cecum mucosa Colon Colonic epithelium Descending colon Lamina propria of mucosa of colon Mucosa of sigmoid colon Mucosa of transverse colon Sigmoid colon

Sixth decade stage Fifth decade stage Third decade stage Seventh decade stage Adult stage Fourth decade stage Eighth decade stage

Normal Crohn disease

Female Male

10x 3' v1 10x 3' v3 10x 3' v2

Cell

Homo sapiens

Medium spiny neuron

Brodmann (1909) area 13 Brodmann (1909) area 24 Brodmann (1909) area 25 Brodmann (1909) area 38 Accessory basal amygdaloid nucleus Agranular insular cortex Anterior cortical amygdaloid nucleus Anterior nuclear group Anterior olfactory nucleus Basolateral amygdaloid nuclear complex Bed nucleus of stria terminalis Body of caudate nucleus Central amygdaloid nucleus Cerebellar nuclear complex Claustrum of brain Corticomedial nuclear complex Dentate gyrus of hippocampal formation Globus pallidus Granular insular cortex Gray matter of midbrain Hippocampal field Hypothalamus Lateral amygdaloid nucleus Lateral geniculate body Lateral nuclear group of thalamus Lateral posterior nucleus of thalamus Mammillary body Medial entorhinal cortex Middle temporal gyrus Nucleus accumbens Perirhinal cortex Piriform cortex Preoptic area Pretectal region Primary auditory cortex Primary motor cortex Pulvinar nucleus Putamen Septal nuclear complex Substantia innominata Substantia nigra Superior temporal gyrus Supraoptic nucleus Uncal ca1 Ventral anterior nucleus of thalamus

42-year-old stage 29-year-old stage 50-year-old stage 60-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Natural killer cell Endothelial cell of lymphatic vessel Cytotoxic t cell Mast cell Cd8-positive, alpha-beta memory t cell, cd45ro-positive Basal cell Schwann cell Smooth muscle cell Plasmacytoid dendritic cell Endothelial cell of vascular tree Basal cell of epidermis Macrophage Innate lymphoid cell Regulatory t cell Helper t cell Plasma cell Cell of skeletal muscle Pericyte Melanocyte of skin Monocyte Suprabasal keratinocyte Conventional dendritic cell Fibroblast Dendritic cell Chondrocyte

Arm skin Nose skin Skin of abdomen Skin of cheek Skin of external ear Skin of forehead Skin of temple

66-year-old stage 69-year-old stage 91-year-old stage 85-year-old stage 53-year-old stage 54-year-old stage 39-year-old stage 56-year-old stage 90-year-old stage 80-year-old stage 51-year-old stage 81-year-old stage 24-year-old stage 23-year-old stage 59-year-old stage 25-year-old stage 77-year-old stage 62-year-old stage 86-year-old stage 70-year-old stage 78-year-old stage 63-year-old stage 73-year-old stage 27-year-old stage

Normal Basal cell carcinoma

Female Male

10x 3' v1 10x 3' v3 10x 3' v2

Cell

Callithrix jacchus

T cell L2/3 intratelencephalic projecting glutamatergic neuron Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Vascular leptomeningeal cell Erythroid lineage cell Smooth muscle cell Inhibitory interneuron Pvalb chandelier gabaergic interneuron Lamp5 gabaergic interneuron Macrophage L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex Microglial cell Vip gabaergic interneuron Myeloid cell L5 extratelencephalic projecting glutamatergic cortical neuron L6b glutamatergic cortical neuron L6 corticothalamic-projecting glutamatergic cortical neuron Pvalb gabaergic interneuron B cell Pericyte Astrocyte L5/6 near-projecting glutamatergic neuron of the primary motor cortex Sst gabaergic interneuron

Dorsolateral prefrontal cortex

Prime adult stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Erythrocyte Early lymphoid progenitor Macrophage Promonocyte Hematopoietic stem cell Common myeloid progenitor Hematopoietic multipotent progenitor cell Megakaryocyte Granulocyte monocyte progenitor cell Promyelocyte Megakaryocyte-erythroid progenitor cell Fraction a pre-pro b cell Vascular associated smooth muscle cell Double negative thymocyte

Bone marrow Gut wall Kidney Liver Mesenteric lymph node Skin of body Spleen Thymus Yolk sac

Carnegie stage 19 13th week post-fertilization stage Carnegie stage 13 14th week post-fertilization stage 15th week post-fertilization stage 17th week post-fertilization stage 12th week post-fertilization stage 16th week post-fertilization stage Carnegie stage 20 9th week post-fertilization stage Carnegie stage 23 10th week post-fertilization stage Carnegie stage 22 11th week post-fertilization stage

Normal

Female Male

10x 5' v1 10x 3' v2

Cell

Callithrix jacchus

Astrocyte

Brodmann (1909) area 23 Brodmann (1909) area 25 Amygdala Anterior hypothalamic region Basal forebrain Brainstem Caudate nucleus Central amygdaloid nucleus Cerebellum lobule Dorsal thalamus Dorsolateral prefrontal cortex Hippocampal formation Lateral amygdaloid nucleus Lateral geniculate body Lateral nuclear group of thalamus Medial amygdaloid nucleus Medial dorsal nucleus of thalamus Nucleus accumbens Parietal cortex Posterior hypothalamic region Prefrontal cortex Primary auditory cortex Primary motor cortex Primary somatosensory cortex Primary visual cortex Putamen Secondary visual cortex Temporal cortex Temporal lobe Thalamic complex Ventral lateral nucleus of thalamus Ventral thalamus

Late adult stage Prime adult stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Natural killer cell Cd16-positive, cd56-dim natural killer cell, human Innate lymphoid cell Cd16-negative, cd56-bright natural killer cell, human

Blood

34-year-old stage 65-year-old stage 26-year-old stage 61-year-old stage 30-year-old stage 29-year-old stage 56-year-old stage 55-year-old stage 28-year-old stage 57-year-old stage 12-year-old stage 35-year-old stage 58-year-old stage 59-year-old stage 25-year-old stage 32-year-old stage 33-year-old stage 64-year-old stage 62-year-old stage 60-year-old stage 31-year-old stage 36-year-old stage 63-year-old stage 11-year-old stage 27-year-old stage

Cytomegalovirus infection Normal

Female Male

10x 3' v3

Cell

Homo sapiens

Oligodendrocyte precursor cell Oligodendrocyte Vascular leptomeningeal cell Pvalb chandelier gabaergic interneuron Lamp5 gabaergic interneuron Microglial cell Vip gabaergic interneuron L2/3-6 intratelencephalic projecting glutamatergic neuron L5 extratelencephalic projecting glutamatergic cortical neuron L6b glutamatergic cortical neuron Pvalb gabaergic interneuron Near-projecting glutamatergic cortical neuron Cerebral cortex endothelial cell Caudal ganglionic eminence derived interneuron Sncg gabaergic interneuron Astrocyte of the cerebral cortex Sst gabaergic interneuron Corticothalamic-projecting glutamatergic cortical neuron

Middle temporal gyrus

42-year-old stage 43-year-old stage 29-year-old stage 50-year-old stage 60-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Mus musculus

Oligodendrocyte precursor cell Vascular leptomeningeal cell Lymphocyte Smooth muscle cell of the brain vasculature Ependymal cell Microglial cell Brain microvascular endothelial cell Pericyte Neuron Perivascular macrophage Astrocyte

Prion disease Normal

10x 3' transcription profiling

Mus musculus

Type 5b cone bipolar cell Type 1 cone bipolar cell (sensu mus) Type 6 cone bipolar cell (sensu mus) Type 5 cone bipolar cell (sensu mus) Type 3a cone bipolar cell Type 7 cone bipolar cell (sensu mus) Type 8 cone bipolar cell (sensu mus) Rod bipolar cell Type 2 cone bipolar cell (sensu mus) Type 3b cone bipolar cell Type 4 cone bipolar cell (sensu mus) Type 5a cone bipolar cell Type 9 cone bipolar cell (sensu mus)

Normal

10x 3' v3 Drop-seq 10x 3' v2

Mus musculus

Type 5b cone bipolar cell Type 1 cone bipolar cell (sensu mus) Type 6 cone bipolar cell (sensu mus) Type 5 cone bipolar cell (sensu mus) Type 3a cone bipolar cell Type 7 cone bipolar cell (sensu mus) Type 8 cone bipolar cell (sensu mus) Rod bipolar cell Type 2 cone bipolar cell (sensu mus) Type 3b cone bipolar cell Type 4 cone bipolar cell (sensu mus) Type 5a cone bipolar cell Type 9 cone bipolar cell (sensu mus)

Retina

5-week-old stage 9-week-old stage 4-month-old stage 12-week-old stage 25-week-old stage 11-week-old stage 7-week-old stage 2-week-old stage 8-week-old stage

Normal

Male

10x 3' v3 Drop-seq 10x 3' v2

Cell