Homo sapiens

Cd4-positive, alpha-beta t cell

T cell

Fourth decade stage Eighth decade stage Ninth decade stage Fifth decade stage Seventh decade stage Third decade stage Sixth decade stage

B-cell non-hodgkin lymphoma

Female Male

10x 5' v1

Cell

Homo sapiens

L2/3-6 intratelencephalic projecting glutamatergic neuron Hippocampal ca1-3 neuron Dentate gyrus neuron L6 corticothalamic-projecting glutamatergic cortical neuron Near-projecting glutamatergic cortical neuron L6b glutamatergic cortical neuron Hippocampal neuron L5 extratelencephalic projecting glutamatergic cortical neuron Amygdala excitatory neuron

Middle temporal gyrus Putamen Brodmann (1909) area 24 Posterior parahippocampal gyrus Brodmann (1909) area 38 Secondary visual cortex Brodmann (1909) area 19 Inferior temporal gyrus Hippocampal formation Dentate gyrus of hippocampal formation Bed nucleus of stria terminalis Primary somatosensory cortex Substantia innominata Body of caudate nucleus Insula Central nucleus of inferior colliculus Central amygdaloid nucleus Granular insular cortex Agranular insular cortex Globus pallidus Basolateral amygdaloid nuclear complex Anterior cingulate cortex Subiculum Primary auditory cortex Medial entorhinal cortex Corticomedial nuclear complex Brodmann (1909) area 46 Lateral entorhinal cortex Brodmann (1909) area 25 Parietal cortex Primary motor cortex Pulvinar nucleus Amygdala Primary visual cortex Hippocampal field Piriform cortex Claustrum of brain Pontine nuclear group Medial dorsal nucleus of thalamus Nucleus accumbens Septal nuclear complex Prefrontal cortex Cuneus cortex

58-year-old stage 42-year-old stage 29-year-old stage

Normal

Male

Snmc-seq2

Nucleus

Homo sapiens

L2/3-6 intratelencephalic projecting glutamatergic neuron Hippocampal ca1-3 neuron Dentate gyrus neuron L6 corticothalamic-projecting glutamatergic cortical neuron Near-projecting glutamatergic cortical neuron L6b glutamatergic cortical neuron Hippocampal neuron L5 extratelencephalic projecting glutamatergic cortical neuron Amygdala excitatory neuron

Middle temporal gyrus Putamen Brodmann (1909) area 24 Posterior parahippocampal gyrus Brodmann (1909) area 38 Secondary visual cortex Brodmann (1909) area 19 Inferior temporal gyrus Hippocampal formation Dentate gyrus of hippocampal formation Bed nucleus of stria terminalis Primary somatosensory cortex Substantia innominata Body of caudate nucleus Insula Central nucleus of inferior colliculus Central amygdaloid nucleus Granular insular cortex Agranular insular cortex Globus pallidus Basolateral amygdaloid nuclear complex Anterior cingulate cortex Subiculum Primary auditory cortex Medial entorhinal cortex Corticomedial nuclear complex Brodmann (1909) area 46 Lateral entorhinal cortex Brodmann (1909) area 25 Parietal cortex Primary motor cortex Pulvinar nucleus Amygdala Primary visual cortex Hippocampal field Piriform cortex Claustrum of brain Pontine nuclear group Medial dorsal nucleus of thalamus Nucleus accumbens Septal nuclear complex Prefrontal cortex Cuneus cortex

58-year-old stage 42-year-old stage 29-year-old stage

Normal

Male

Snmc-seq2

Nucleus

Homo sapiens

Neural progenitor cell Neuron

Forebrain

Carnegie stage 01

Normal

Female Male

10x 3' v3

Cell

Macaca mulatta

Macrophage Mast cell Epithelial cell Neutrophil B cell T cell Eosinophil

Disease

Seq-well

Homo sapiens

Naive b cell Innate lymphoid cell Cd4-positive, alpha-beta t cell Platelet Naive regulatory t cell Naive thymus-derived cd4-positive, alpha-beta t cell Mucosal invariant t cell Effector memory cd4-positive, alpha-beta t cell Cd16-negative, cd56-bright natural killer cell, human Myeloid dendritic cell, human Cd14-positive monocyte Double negative thymocyte Plasmablast Conventional dendritic cell Naive thymus-derived cd8-positive, alpha-beta t cell Central memory cd4-positive, alpha-beta t cell Effector memory cd8-positive, alpha-beta t cell Hematopoietic stem cell Central memory cd8-positive, alpha-beta t cell B cell Cd8-positive, alpha-beta t cell Cd4-positive, alpha-beta cytotoxic t cell Erythrocyte Memory b cell Plasmacytoid dendritic cell Cd14-low, cd16-positive monocyte Memory regulatory t cell Natural killer cell Gamma-delta t cell

Blood

Normal

10x 3' v3

Cell

Homo sapiens

Astrocyte Oligodendrocyte precursor cell Oligodendrocyte Microglial cell Endothelial cell Neuron

Frontal cortex

66-year-old stage 70-year-old stage 50-year-old stage 71-year-old stage 59-year-old stage 54-year-old stage 47-year-old stage 56-year-old stage 58-year-old stage 68-year-old stage 61-year-old stage 51-year-old stage 72-year-old stage 73-year-old stage 43-year-old stage

Normal Amyotrophic lateral sclerosis 26 with or without frontotemporal dementia Amyotrophic lateral sclerosis

Female Male

10x 3' v3

Nucleus

Homo sapiens

Be cell Naive b cell Transitional stage b cell Plasma cell Memory b cell

Blood

32-year-old stage 57-year-old stage 62-year-old stage 60-year-old stage 64-year-old stage 25-year-old stage 33-year-old stage 65-year-old stage 27-year-old stage 28-year-old stage 36-year-old stage 63-year-old stage 59-year-old stage 31-year-old stage 56-year-old stage 58-year-old stage 61-year-old stage 34-year-old stage 35-year-old stage 30-year-old stage 26-year-old stage 12-year-old stage 29-year-old stage 55-year-old stage 11-year-old stage

Normal Cytomegalovirus infection

Female Male

10x 3' v3

Cell

Mus musculus

Glutamatergic neuron Astrocyte Oligodendrocyte precursor cell Oligodendrocyte Gabaergic neuron Macrophage Leptomeningeal cell Pericyte Endothelial cell Smooth muscle cell

Primary motor cortex

Prime adult stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Macrophage Extravillous trophoblast Perivascular cell Endothelial cell of placenta Placental villous trophoblast Fibroblast Hofbauer cell

Placenta

Carnegie stage 14 Carnegie stage 22 Carnegie stage 09 Carnegie stage 12 Carnegie stage 11 Carnegie stage 13 Carnegie stage 23 Carnegie stage 18

Normal Plasmodium malariae malaria Toxoplasmosis Listeriosis

Female

10x 3' v3

Cell

Pan troglodytes

L2/3 intratelencephalic projecting glutamatergic neuron Inhibitory interneuron Vascular leptomeningeal cell Astrocyte Oligodendrocyte precursor cell Oligodendrocyte Macrophage L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex Erythroid lineage cell L6 corticothalamic-projecting glutamatergic cortical neuron L5/6 near-projecting glutamatergic neuron of the primary motor cortex Sst gabaergic interneuron Microglial cell Lamp5 gabaergic interneuron L6b glutamatergic cortical neuron Pericyte Endothelial cell B cell T cell Smooth muscle cell L5 extratelencephalic projecting glutamatergic cortical neuron Vip gabaergic interneuron Pvalb gabaergic interneuron Pvalb chandelier gabaergic interneuron Myeloid cell

Dorsolateral prefrontal cortex

Prime adult stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Macrophage Mast cell Neutrophil Monocyte Fibroblast Malignant cell Hepatocyte Endothelial cell B cell Plasma cell Erythrocyte Mature nk t cell T cell Keratinocyte Chondrocyte

Axilla Neck Breast Liver Lung Bone spine

32-year-old stage 50-year-old stage 57-year-old stage 52-year-old stage 60-year-old stage 44-year-old stage 64-year-old stage 40-year-old stage 37-year-old stage 28-year-old stage 36-year-old stage 54-year-old stage 58-year-old stage 35-year-old stage 53-year-old stage 30-year-old stage 43-year-old stage 29-year-old stage 38-year-old stage 41-year-old stage 55-year-old stage

Breast cancer

Female

10x 3' v3 10x 3' v2

Cell