Homo sapiens

Circulating fibrocyte Common myeloid progenitor Radial glial cell Schwann cell Fibroblast of choroid plexus Capillary endothelial cell Erythroid progenitor cell Innate lymphoid cell Oligodendrocyte precursor cell Platelet Endothelial cell of arteriole Neural crest cell Glioblast (sensu vertebrata) Meningeal macrophage Neuroblast (sensu vertebrata) Arachnoid barrier cell Forebrain neuroblast Promyelocyte Mast cell Mucosa-associated lymphoid tissue macrophage Epithelial cell Choroid plexus macrophage Monocyte Interneuron Megakaryocyte Perivascular cell Neural progenitor cell Leptomeningeal cell Schwann cell precursor Reticulocyte Vein endothelial cell Microglial cell Fibroblast Metamyelocyte Tip cell Mechanoreceptor cell Pericyte Endothelial cell Embryonic blood vessel endothelial progenitor cell Pinealocyte Mesenchymal cell Erythroblast B cell Neuronal-restricted precursor Forebrain radial glial cell Retinal cell Dendritic cell Perivascular macrophage Smooth muscle cell Retinal ganglion cell Neuron Natural killer cell Chondrocyte Endothelial cell of artery Choroid plexus epithelial cell Mesothelial cell of dura mater Spinal cord radial glial cell Mesenchyme condensation cell

Meninx Brain meninx Forebrain meninges

9th week post-fertilization stage 13th week post-fertilization stage 12th week post-fertilization stage 10th week post-fertilization stage Carnegie stage 23 Carnegie stage 21 Carnegie stage 20 Carnegie stage 18 Carnegie stage 16

Normal

Female Male

10x 3' v3

Cell

Mus musculus

Osteoblast Schwann cell Vomeronasal sensory neuron Ciliated epithelial cell Osteoclast Oligodendrocyte Cd4-positive, alpha-beta t cell Ionocyte Macrophage Granulocyte monocyte progenitor cell Stromal cell Glandular secretory epithelial cell Mast cell Basal cell Olfactory receptor cell Epithelial cell Sustentacular cell Neutrophil Monocyte Neural progenitor cell Tuft cell Serous secreting cell Fibroblast Group 3 innate lymphoid cell Hematopoietic stem cell Pericyte Endothelial cell Alpha-beta t cell B cell Cd8-positive, alpha-beta t cell Group 2 innate lymphoid cell Dendritic cell Plasma cell Plasmacytoid dendritic cell Precursor b cell Smooth muscle cell Natural killer cell Chondrocyte Gamma-delta t cell Goblet cell

Normal Influenza

10x 3' v3

Homo sapiens

L2/3-6 intratelencephalic projecting glutamatergic neuron Caudal ganglionic eminence derived interneuron Cerebral cortex endothelial cell Vascular leptomeningeal cell Oligodendrocyte precursor cell Oligodendrocyte Astrocyte of the cerebral cortex Sncg gabaergic interneuron Near-projecting glutamatergic cortical neuron Sst gabaergic interneuron Microglial cell Lamp5 gabaergic interneuron L6b glutamatergic cortical neuron Corticothalamic-projecting glutamatergic cortical neuron L5 extratelencephalic projecting glutamatergic cortical neuron Vip gabaergic interneuron Pvalb gabaergic interneuron Pvalb chandelier gabaergic interneuron

Middle temporal gyrus

50-year-old stage 60-year-old stage Adult stage 42-year-old stage 43-year-old stage 29-year-old stage

Normal

Female Male

Smart-seq v4 10x 3' v3

Nucleus

Homo sapiens

Ciliated epithelial cell Glial cell Mesothelial cell Basal cell Epithelial cell Epithelial cell of lung Enteroendocrine cell Hepatocyte Pericyte Endothelial cell Peripheral nervous system neuron Myeloid leukocyte Mesenchymal cell Erythroblast B cell Mature nk t cell Intestinal epithelial cell Chondrocyte Intestine goblet cell

Body of stomach Ileum Liver Lung Small intestine Esophagus Jejunum Pyloric antrum Duodenum Epithelium of trachea Colon Stomach

9th week post-fertilization stage 13th week post-fertilization stage 12th week post-fertilization stage Embryonic stage 11th week post-fertilization stage 21st week post-fertilization stage 19th week post-fertilization stage 17th week post-fertilization stage 15th week post-fertilization stage 18th week post-fertilization stage

Normal

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Astrocyte

Inferior frontal gyrus Middle temporal gyrus Putamen Brodmann (1909) area 24 Cerebellar vermis Posterior parahippocampal gyrus Anterior olfactory nucleus Brodmann (1909) area 38 Pretectal region Subicular complex Gray matter of midbrain Brodmann (1909) area 14 Brodmann (1909) area 19 Inferior temporal gyrus Hypothalamus Brodmann (1909) area 32 Cerebrocerebellum Dentate gyrus of hippocampal formation Lateral geniculate body Bed nucleus of stria terminalis Median tuberal portion Brodmann (1909) area 13 Primary somatosensory cortex Medial geniculate body Preoptic area Substantia innominata Perirhinal cortex Body of caudate nucleus Extrastriate cortex Lateral nuclear group of thalamus Dorsal tegmental nucleus Brodmann (1909) area 23 Centromedian nucleus of thalamus Brodmann (1909) area 35 Epithalamus Substantia nigra Central amygdaloid nucleus Rostral ca3 Granular insular cortex Agranular insular cortex Globus pallidus Basolateral amygdaloid nuclear complex Parabrachial nucleus Ventral anterior nucleus of thalamus Nucleus of dorsal thalamus Anterior cortical amygdaloid nucleus Anterior nuclear group Brodmann (1909) area 43 Primary auditory cortex Medial entorhinal cortex Red nucleus Corticomedial nuclear complex Lateral posterior nucleus of thalamus Brodmann (1909) area 46 Nucleus of medulla oblongata Supraoptic nucleus Uncal ca1 Cerebellar nuclear complex Temporal fusiform gyrus Lateral entorhinal cortex Brodmann (1909) area 25 Midbrain nucleus Primary motor cortex Pulvinar nucleus Pontine tegmentum Primary visual cortex Subthalamic nucleus Spinal cord Superior parietal cortex Hippocampal field Inferior olivary complex Piriform cortex Lateral amygdaloid nucleus Brodmann (1909) area 40 Claustrum of brain Midbrain tectum Mammillary body Pontine reticular formation Pontine nuclear group Medial dorsal nucleus of thalamus Retrosplenial region Nucleus accumbens Medial zone of hypothalamus Intralaminar nuclear group Accessory basal amygdaloid nucleus Superior temporal gyrus Septal nuclear complex Cuneus cortex

50-year-old stage 60-year-old stage 42-year-old stage 29-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Type ec enteroendocrine cell Epithelial cell Paneth cell Stem cell Type l enteroendocrine cell Tuft cell Enterocyte Goblet cell

Ileum Ileum lamina propria Small intestine Epithelium of small intestine Lamina propria of small intestine Ileal epithelium

Fourth decade stage Eighth decade stage Fifth decade stage Seventh decade stage Third decade stage Sixth decade stage

Normal Crohn disease

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

L2/3-6 intratelencephalic projecting glutamatergic neuron Caudal ganglionic eminence derived interneuron Cerebral cortex endothelial cell Vascular leptomeningeal cell Oligodendrocyte precursor cell Oligodendrocyte Astrocyte of the cerebral cortex Sncg gabaergic interneuron Near-projecting glutamatergic cortical neuron Sst gabaergic interneuron Microglial cell Lamp5 gabaergic interneuron L6b glutamatergic cortical neuron Corticothalamic-projecting glutamatergic cortical neuron L5 extratelencephalic projecting glutamatergic cortical neuron Vip gabaergic interneuron Pvalb gabaergic interneuron Pvalb chandelier gabaergic interneuron

Primary somatosensory cortex

50-year-old stage 60-year-old stage 42-year-old stage 43-year-old stage 29-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Innate lymphoid cell Cd4-positive, alpha-beta t cell Leukocyte Macrophage Mast cell Naive t cell Monocyte Conventional dendritic cell B cell Cd8-positive, alpha-beta t cell Dendritic cell Plasma cell Regulatory t cell T cell Plasmacytoid dendritic cell Natural killer cell

Lamina propria of mucosa of colon Caecum epithelium Colonic epithelium Cecum mucosa Mucosa of transverse colon Sigmoid colon Colon Descending colon Ascending colon Mucosa of sigmoid colon

Fourth decade stage Eighth decade stage Adult stage Fifth decade stage Seventh decade stage Third decade stage Sixth decade stage

Normal Crohn disease

Female Male

10x 3' v3 10x 3' v1 10x 3' v2

Cell

Homo sapiens

Schwann cell Cd8-positive, alpha-beta memory t cell, cd45ro-positive Innate lymphoid cell Endothelial cell of lymphatic vessel Cytotoxic t cell Helper t cell Macrophage Melanocyte of skin Mast cell Basal cell Endothelial cell of vascular tree Monocyte Cell of skeletal muscle Basal cell of epidermis Conventional dendritic cell Fibroblast Pericyte Dendritic cell Plasma cell Regulatory t cell Plasmacytoid dendritic cell Suprabasal keratinocyte Smooth muscle cell Natural killer cell Chondrocyte

Arm skin Skin of forehead Skin of cheek Skin of abdomen Skin of external ear Nose skin Skin of temple

80-year-old stage 85-year-old stage 91-year-old stage 66-year-old stage 70-year-old stage 77-year-old stage 86-year-old stage 62-year-old stage 25-year-old stage 27-year-old stage 23-year-old stage 78-year-old stage 63-year-old stage 59-year-old stage 54-year-old stage 56-year-old stage 51-year-old stage 53-year-old stage 73-year-old stage 24-year-old stage 39-year-old stage 90-year-old stage 69-year-old stage 81-year-old stage

Normal Basal cell carcinoma

Female Male

10x 3' v3 10x 3' v1 10x 3' v2

Cell

Homo sapiens

Neuron

Middle temporal gyrus Putamen Brodmann (1909) area 24 Anterior olfactory nucleus Brodmann (1909) area 38 Pretectal region Gray matter of midbrain Hypothalamus Dentate gyrus of hippocampal formation Lateral geniculate body Bed nucleus of stria terminalis Brodmann (1909) area 13 Preoptic area Substantia innominata Perirhinal cortex Body of caudate nucleus Lateral nuclear group of thalamus Substantia nigra Central amygdaloid nucleus Granular insular cortex Agranular insular cortex Globus pallidus Basolateral amygdaloid nuclear complex Ventral anterior nucleus of thalamus Anterior cortical amygdaloid nucleus Anterior nuclear group Primary auditory cortex Medial entorhinal cortex Corticomedial nuclear complex Lateral posterior nucleus of thalamus Supraoptic nucleus Uncal ca1 Cerebellar nuclear complex Brodmann (1909) area 25 Primary motor cortex Pulvinar nucleus Hippocampal field Piriform cortex Lateral amygdaloid nucleus Claustrum of brain Mammillary body Nucleus accumbens Accessory basal amygdaloid nucleus Superior temporal gyrus Septal nuclear complex

50-year-old stage 60-year-old stage 42-year-old stage 29-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Callithrix jacchus

L2/3 intratelencephalic projecting glutamatergic neuron Inhibitory interneuron Vascular leptomeningeal cell Astrocyte Oligodendrocyte precursor cell Oligodendrocyte Macrophage L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex Erythroid lineage cell L6 corticothalamic-projecting glutamatergic cortical neuron L5/6 near-projecting glutamatergic neuron of the primary motor cortex Sst gabaergic interneuron Microglial cell Lamp5 gabaergic interneuron L6b glutamatergic cortical neuron Pericyte Endothelial cell B cell T cell Smooth muscle cell L5 extratelencephalic projecting glutamatergic cortical neuron Vip gabaergic interneuron Pvalb gabaergic interneuron Pvalb chandelier gabaergic interneuron Myeloid cell

Dorsolateral prefrontal cortex

Prime adult stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Common myeloid progenitor Promonocyte Macrophage Granulocyte monocyte progenitor cell Promyelocyte Megakaryocyte-erythroid progenitor cell Fraction a pre-pro b cell Megakaryocyte Double negative thymocyte Vascular associated smooth muscle cell Early lymphoid progenitor Hematopoietic stem cell Erythrocyte Hematopoietic multipotent progenitor cell

Thymus Mesenteric lymph node Liver Spleen Kidney Bone marrow Gut wall Yolk sac Skin of body

9th week post-fertilization stage 13th week post-fertilization stage 12th week post-fertilization stage 10th week post-fertilization stage Carnegie stage 22 11th week post-fertilization stage 17th week post-fertilization stage 15th week post-fertilization stage Carnegie stage 19 Carnegie stage 13 14th week post-fertilization stage 16th week post-fertilization stage Carnegie stage 23 Carnegie stage 20

Normal

Female Male

10x 5' v1 10x 3' v2

Cell