Homo sapiens

Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Microglial cell Neuron Astrocyte

Frontal cortex

66-year-old stage 43-year-old stage 71-year-old stage 61-year-old stage 54-year-old stage 68-year-old stage 56-year-old stage 50-year-old stage 51-year-old stage 72-year-old stage 58-year-old stage 59-year-old stage 70-year-old stage 47-year-old stage 73-year-old stage

Amyotrophic lateral sclerosis Amyotrophic lateral sclerosis 26 with or without frontotemporal dementia Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Be cell Memory b cell Plasma cell Transitional stage b cell Naive b cell

Blood

34-year-old stage 65-year-old stage 26-year-old stage 61-year-old stage 30-year-old stage 29-year-old stage 56-year-old stage 55-year-old stage 28-year-old stage 57-year-old stage 12-year-old stage 35-year-old stage 58-year-old stage 59-year-old stage 25-year-old stage 32-year-old stage 33-year-old stage 64-year-old stage 62-year-old stage 60-year-old stage 31-year-old stage 36-year-old stage 63-year-old stage 11-year-old stage 27-year-old stage

Cytomegalovirus infection Normal

Female Male

10x 3' v3

Cell

Mus musculus

Glutamatergic neuron Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Smooth muscle cell Macrophage Leptomeningeal cell Pericyte Astrocyte Gabaergic neuron

Primary motor cortex

Prime adult stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Perivascular cell Extravillous trophoblast Placental villous trophoblast Macrophage Endothelial cell of placenta Hofbauer cell Fibroblast

Placenta

Carnegie stage 11 Carnegie stage 14 Carnegie stage 09 Carnegie stage 13 Carnegie stage 23 Carnegie stage 12 Carnegie stage 22 Carnegie stage 18

Plasmodium malariae malaria Listeriosis Toxoplasmosis Normal

Female

10x 3' v3

Cell

Pan troglodytes

T cell L2/3 intratelencephalic projecting glutamatergic neuron Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Vascular leptomeningeal cell Erythroid lineage cell Smooth muscle cell Inhibitory interneuron Pvalb chandelier gabaergic interneuron Lamp5 gabaergic interneuron Macrophage L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex Microglial cell Vip gabaergic interneuron Myeloid cell L5 extratelencephalic projecting glutamatergic cortical neuron L6b glutamatergic cortical neuron L6 corticothalamic-projecting glutamatergic cortical neuron Pvalb gabaergic interneuron B cell Pericyte Astrocyte L5/6 near-projecting glutamatergic neuron of the primary motor cortex Sst gabaergic interneuron

Dorsolateral prefrontal cortex

Prime adult stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

T cell Neutrophil Hepatocyte Erythrocyte Endothelial cell Mature nk t cell Mast cell Macrophage Keratinocyte Plasma cell Malignant cell B cell Monocyte Fibroblast Chondrocyte

Axilla Bone spine Breast Liver Lung Neck

37-year-old stage 43-year-old stage 53-year-old stage 52-year-old stage 54-year-old stage 30-year-old stage 44-year-old stage 29-year-old stage 38-year-old stage 55-year-old stage 50-year-old stage 28-year-old stage 57-year-old stage 35-year-old stage 58-year-old stage 32-year-old stage 64-year-old stage 41-year-old stage 60-year-old stage 36-year-old stage 40-year-old stage

Breast cancer

Female

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Tip cell Glioblast (sensu vertebrata) Natural killer cell Erythroid progenitor cell Oligodendrocyte precursor cell Mechanoreceptor cell Arachnoid barrier cell Perivascular cell Endothelial cell Retinal ganglion cell Mast cell Platelet Endothelial cell of arteriole Mucosa-associated lymphoid tissue macrophage Mesenchyme condensation cell Endothelial cell of artery Capillary endothelial cell Schwann cell Smooth muscle cell Epithelial cell Neural crest cell Choroid plexus macrophage Microglial cell Innate lymphoid cell Forebrain neuroblast Forebrain radial glial cell Neuroblast (sensu vertebrata) Embryonic blood vessel endothelial progenitor cell Radial glial cell Meningeal macrophage Leptomeningeal cell Pinealocyte Common myeloid progenitor Vein endothelial cell Mesenchymal cell Megakaryocyte Interneuron Metamyelocyte Choroid plexus epithelial cell B cell Pericyte Spinal cord radial glial cell Circulating fibrocyte Promyelocyte Neuron Retinal cell Perivascular macrophage Reticulocyte Neuronal-restricted precursor Monocyte Fibroblast of choroid plexus Erythroblast Mesothelial cell of dura mater Fibroblast Dendritic cell Neural progenitor cell Schwann cell precursor Chondrocyte

Brain meninx Forebrain meninges Meninx

13th week post-fertilization stage 12th week post-fertilization stage Carnegie stage 20 9th week post-fertilization stage Carnegie stage 23 10th week post-fertilization stage Carnegie stage 21 Carnegie stage 16 Carnegie stage 18

Normal

Female Male

10x 3' v3

Cell

Mus musculus

Osteoblast Neutrophil Sustentacular cell Stromal cell Natural killer cell Gamma-delta t cell Endothelial cell Oligodendrocyte Alpha-beta t cell Mast cell Cd8-positive, alpha-beta t cell Group 2 innate lymphoid cell Serous secreting cell Basal cell Schwann cell Ionocyte Smooth muscle cell Epithelial cell Plasmacytoid dendritic cell Precursor b cell Olfactory receptor cell Group 3 innate lymphoid cell Goblet cell Tuft cell Macrophage Vomeronasal sensory neuron Hematopoietic stem cell Plasma cell Cd4-positive, alpha-beta t cell Glandular secretory epithelial cell Ciliated epithelial cell B cell Pericyte Granulocyte monocyte progenitor cell Monocyte Fibroblast Osteoclast Dendritic cell Neural progenitor cell Chondrocyte

Normal Influenza

10x 3' v3

Homo sapiens

Oligodendrocyte precursor cell Oligodendrocyte Vascular leptomeningeal cell Pvalb chandelier gabaergic interneuron Lamp5 gabaergic interneuron Microglial cell Vip gabaergic interneuron L2/3-6 intratelencephalic projecting glutamatergic neuron L5 extratelencephalic projecting glutamatergic cortical neuron L6b glutamatergic cortical neuron Pvalb gabaergic interneuron Near-projecting glutamatergic cortical neuron Cerebral cortex endothelial cell Caudal ganglionic eminence derived interneuron Sncg gabaergic interneuron Astrocyte of the cerebral cortex Sst gabaergic interneuron Corticothalamic-projecting glutamatergic cortical neuron

Middle temporal gyrus

42-year-old stage 43-year-old stage 29-year-old stage 50-year-old stage Adult stage 60-year-old stage

Normal

Female Male

Smart-seq v4 10x 3' v3

Nucleus

Homo sapiens

Hepatocyte Intestine goblet cell Endothelial cell Mature nk t cell Basal cell Peripheral nervous system neuron Epithelial cell Enteroendocrine cell Glial cell Intestinal epithelial cell Mesenchymal cell Mesothelial cell Ciliated epithelial cell B cell Pericyte Myeloid leukocyte Epithelial cell of lung Erythroblast Chondrocyte

Body of stomach Colon Duodenum Epithelium of trachea Esophagus Ileum Jejunum Liver Lung Pyloric antrum Small intestine Stomach

19th week post-fertilization stage 21st week post-fertilization stage 13th week post-fertilization stage 15th week post-fertilization stage 17th week post-fertilization stage 12th week post-fertilization stage 9th week post-fertilization stage Embryonic stage 18th week post-fertilization stage 11th week post-fertilization stage

Normal

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Astrocyte

Brodmann (1909) area 13 Brodmann (1909) area 14 Brodmann (1909) area 19 Brodmann (1909) area 23 Brodmann (1909) area 24 Brodmann (1909) area 25 Brodmann (1909) area 32 Brodmann (1909) area 35 Brodmann (1909) area 38 Brodmann (1909) area 40 Brodmann (1909) area 43 Brodmann (1909) area 46 Accessory basal amygdaloid nucleus Agranular insular cortex Anterior cortical amygdaloid nucleus Anterior nuclear group Anterior olfactory nucleus Basolateral amygdaloid nuclear complex Bed nucleus of stria terminalis Body of caudate nucleus Central amygdaloid nucleus Centromedian nucleus of thalamus Cerebellar nuclear complex Cerebellar vermis Cerebrocerebellum Claustrum of brain Corticomedial nuclear complex Cuneus cortex Dentate gyrus of hippocampal formation Dorsal tegmental nucleus Epithalamus Extrastriate cortex Globus pallidus Granular insular cortex Gray matter of midbrain Hippocampal field Hypothalamus Inferior frontal gyrus Inferior olivary complex Inferior temporal gyrus Intralaminar nuclear group Lateral amygdaloid nucleus Lateral entorhinal cortex Lateral geniculate body Lateral nuclear group of thalamus Lateral posterior nucleus of thalamus Mammillary body Medial dorsal nucleus of thalamus Medial entorhinal cortex Medial geniculate body Medial zone of hypothalamus Median tuberal portion Midbrain nucleus Midbrain tectum Middle temporal gyrus Nucleus accumbens Nucleus of dorsal thalamus Nucleus of medulla oblongata Parabrachial nucleus Perirhinal cortex Piriform cortex Pontine nuclear group Pontine reticular formation Pontine tegmentum Posterior parahippocampal gyrus Preoptic area Pretectal region Primary auditory cortex Primary motor cortex Primary somatosensory cortex Primary visual cortex Pulvinar nucleus Putamen Red nucleus Retrosplenial region Rostral ca3 Septal nuclear complex Spinal cord Subicular complex Substantia innominata Substantia nigra Subthalamic nucleus Superior parietal cortex Superior temporal gyrus Supraoptic nucleus Temporal fusiform gyrus Uncal ca1 Ventral anterior nucleus of thalamus

42-year-old stage 29-year-old stage 50-year-old stage 60-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Stem cell Paneth cell Epithelial cell Goblet cell Tuft cell Type ec enteroendocrine cell Enterocyte Type l enteroendocrine cell

Epithelium of small intestine Ileal epithelium Ileum Ileum lamina propria Lamina propria of small intestine Small intestine

Sixth decade stage Fifth decade stage Third decade stage Seventh decade stage Fourth decade stage Eighth decade stage

Normal Crohn disease

Female Male

10x 3' v3 10x 3' v2

Cell