Homo sapiens

Central memory cd4-positive, alpha-beta t cell T cell Basophilic erythroblast Cd14-positive, cd16-positive monocyte Natural killer cell Erythroid progenitor cell Small pre-b-ii cell Stromal cell of bone marrow Pro-b cell Late pro-b cell Effector memory cd4-positive, alpha-beta t cell Plasmacytoid dendritic cell, human Pre-conventional dendritic cell Basophil mast progenitor cell Megakaryocyte progenitor cell Cd8-positive, alpha-beta memory t cell Naive thymus-derived cd8-positive, alpha-beta t cell Cd4-positive, cd25-positive, alpha-beta regulatory t cell Large pre-b-ii cell Mature b cell Promonocyte Polychromatophilic erythroblast Hematopoietic stem cell Common myeloid progenitor Plasma cell Cd14-positive monocyte Hematopoietic multipotent progenitor cell Megakaryocyte Hematopoietic oligopotent progenitor cell Orthochromatic erythroblast Granulocyte monocyte progenitor cell Naive thymus-derived cd4-positive, alpha-beta t cell Common lymphoid progenitor Immature b cell Megakaryocyte-erythroid progenitor cell Central memory cd8-positive, alpha-beta t cell Conventional dendritic cell Dendritic cell Cd16-negative, cd56-bright natural killer cell, human Effector memory cd8-positive, alpha-beta t cell

Bone marrow

66-year-old stage 26-year-old stage 43-year-old stage 52-year-old stage 30-year-old stage 39-year-old stage 29-year-old stage 56-year-old stage 55-year-old stage 84-year-old stage 50-year-old stage 28-year-old stage 57-year-old stage 24-year-old stage 35-year-old stage 58-year-old stage 59-year-old stage 67-year-old stage Late adult stage 32-year-old stage 41-year-old stage 46-year-old stage 60-year-old stage 31-year-old stage 36-year-old stage 19-year-old stage 47-year-old stage Prime adult stage Young adult stage

Normal

Female Male

10x 3' v3 10x 3' v2

Cell

Mus musculus

T cell Neutrophil Hepatocyte Endothelial cell Plasmacytoid dendritic cell Hepatic stellate cell Macrophage Hepatic portal fibroblast Cholangiocyte B cell

Normal

10x 3' v3

Homo sapiens

Cycling t cell Gamma-delta t cell Cd8-positive, alpha-beta memory t cell Group 3 innate lymphoid cell Naive thymus-derived cd8-positive, alpha-beta t cell T-helper 17 cell Cd16-positive, cd56-dim natural killer cell, human Regulatory t cell T follicular helper cell Cd4-positive, alpha-beta memory t cell Naive thymus-derived cd4-positive, alpha-beta t cell Mucosal invariant t cell Cd16-negative, cd56-bright natural killer cell, human Effector memory cd8-positive, alpha-beta t cell

Ascending colon Body of stomach Buccal mucosa Caecum Colon Colonic epithelium Colonic mucosa Descending colon Duodenal epithelium Duodenum Epithelium of esophagus Epithelium of rectum Epithelium of small intestine Epithelium of stomach Esophagus Gingiva Ileal epithelium Ileum Ileum lamina propria Intestine Jejunum Labial gland Lamina propria of mucosa of colon Lamina propria of small intestine Mesenteric lymph node Parotid gland Periodontium Pyloric antrum Pylorus Rectosigmoid junction Rectum Sigmoid colon Small intestine Stomach Transverse colon Vermiform appendix

66-year-old stage 69-year-old stage Carnegie stage 19 37-year-old stage 75-year-old stage Pediatric stage 19th week post-fertilization stage 21-year-old stage 13-year-old stage 21st week post-fertilization stage 34-year-old stage 65-year-old stage 26-year-old stage 43-year-old stage Sixth decade stage 87-year-old stage 13th week post-fertilization stage 85-year-old stage 61-year-old stage 2-year-old stage 52-year-old stage 54-year-old stage 68-year-old stage 48-year-old stage 30-year-old stage 39-year-old stage 44-year-old stage 29-year-old stage 56-year-old stage Fifth decade stage 55-year-old stage 84-year-old stage 15th week post-fertilization stage 50-year-old stage 80-year-old stage 28-year-old stage 51-year-old stage 17th week post-fertilization stage 57-year-old stage 12-year-old stage 72-year-old stage 12th week post-fertilization stage Third decade stage 16th week post-fertilization stage 81-year-old stage 9th week post-fertilization stage 74-year-old stage 9-year-old stage 10th week post-fertilization stage 14-year-old stage 24-year-old stage 23-year-old stage 35-year-old stage Seventh decade stage 58-year-old stage 59-year-old stage Adult stage 67-year-old stage 18th week post-fertilization stage Carnegie stage 17 2-month-old stage 32-year-old stage 77-year-old stage 33-year-old stage Carnegie stage 22 45-year-old stage 62-year-old stage 86-year-old stage 41-year-old stage 70-year-old stage 46-year-old stage 60-year-old stage 31-year-old stage Fourth decade stage 22-year-old stage Newborn stage (0-28 days) 63-year-old stage Eighth decade stage 76-year-old stage Prime adult stage 5-year-old stage 11-year-old stage 6-year-old stage Young adult stage 10-year-old stage 4-year-old stage 11th week post-fertilization stage Juvenile stage (5-14 yo)

Gastric cancer Inflammatory bowel disease Colorectal cancer Ulcerative colitis Normal Crohn disease

Female Male

10x 3' v1 10x 5' v2 10x 5' transcription profiling 10x 5' v1 10x 3' v3 10x 3' v2

Cell

Mus musculus

Granulocyte Central nervous system macrophage Kupffer cell Adipose macrophage Plasmacytoid dendritic cell Microglial cell Hematopoietic stem cell Myeloid suppressor cell Monocyte Conventional dendritic cell Osteoclast

Embryo

Theiler stage 22 Theiler stage 27 Theiler stage 24 Theiler stage 18 Theiler stage 25 Theiler stage 14 Theiler stage 16 Theiler stage 17 Theiler stage 15 Theiler stage 19 Theiler stage 26 Theiler stage 13 Theiler stage 20 Theiler stage 12 Theiler stage 21 Theiler stage 23

Normal

Female Male

Sci-rna-seq3

Nucleus

Callithrix jacchus

Oligodendrocyte

Brodmann (1909) area 23 Brodmann (1909) area 25 Amygdala Anterior hypothalamic region Basal forebrain Brainstem Caudate nucleus Central amygdaloid nucleus Cerebellum lobule Dorsal thalamus Dorsolateral prefrontal cortex Hippocampal formation Lateral amygdaloid nucleus Lateral geniculate body Lateral nuclear group of thalamus Medial amygdaloid nucleus Medial dorsal nucleus of thalamus Nucleus accumbens Parietal cortex Posterior hypothalamic region Prefrontal cortex Primary auditory cortex Primary motor cortex Primary somatosensory cortex Primary visual cortex Putamen Secondary visual cortex Temporal cortex Temporal lobe Thalamic complex Ventral lateral nucleus of thalamus Ventral thalamus

Late adult stage Prime adult stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Neutrophil Periportal region hepatocyte Dendritic cell, human Endothelial cell of periportal hepatic sinusoid Natural killer cell Centrilobular region hepatocyte Midzonal region hepatocyte Inflammatory macrophage Leukocyte Classical monocyte Plasmacytoid dendritic cell Hepatic stellate cell Macrophage Effector memory cd8-positive, alpha-beta t cell, terminally differentiated Endothelial cell of pericentral hepatic sinusoid Cd16-positive, cd56-dim natural killer cell, human Cholangiocyte Plasma cell Cd4-positive, alpha-beta t cell B cell Mucosal invariant t cell Conventional dendritic cell Fibroblast Cd16-negative, cd56-bright natural killer cell, human Effector memory cd8-positive, alpha-beta t cell Non-classical monocyte

Caudate lobe of liver Liver

66-year-old stage 69-year-old stage 75-year-old stage 21-year-old stage 34-year-old stage 65-year-old stage 26-year-old stage 53-year-old stage 52-year-old stage 68-year-old stage 44-year-old stage 55-year-old stage 28-year-old stage 72-year-old stage 49-year-old stage 58-year-old stage Adult stage 67-year-old stage 77-year-old stage 64-year-old stage 45-year-old stage 41-year-old stage 70-year-old stage 46-year-old stage 73-year-old stage Prime adult stage Young adult stage

Normal

Female Male

10x 3' v3 Cel-seq2 10x 3' v2

Cell Nucleus

Mus musculus

Neural stem cell Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Microglial cell Leptomeningeal cell Pericyte Astrocyte

Anterior cerebral artery Anterior olfactory nucleus Caudate-putamen Cerebral cortex Dentate gyrus of hippocampal formation Hippocampal field Lateral septal complex Nucleus accumbens Olfactory cortex Orbitofrontal cortex Pallidum Piriform cortex Primary auditory cortex Primary motor cortex Primary somatosensory cortex Secondary somatosensory cortex

Prime adult stage

Normal

Male

Scatac-seq

Nucleus

Homo sapiens

T cell Neutrophil Natural killer cell Endothelial cell Mast cell Smooth muscle cell Macrophage Plasma cell B cell Monocyte Fibroblast Dendritic cell

Carotid artery segment Coronary artery Femoral artery

66-year-old stage 75-year-old stage 65-year-old stage 89-year-old stage 87-year-old stage 71-year-old stage 54-year-old stage 82-year-old stage 80-year-old stage 81-year-old stage 74-year-old stage 58-year-old stage 59-year-old stage 67-year-old stage 77-year-old stage 64-year-old stage 62-year-old stage 46-year-old stage 78-year-old stage 76-year-old stage 79-year-old stage 83-year-old stage

Atherosclerosis

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Glioblast Cell Erythrocyte Oligodendrocyte Neuroblast (sensu nematoda and protostomia) Neuroplacodal cell Neural crest cell Macrophage Neuroblast (sensu vertebrata) Radial glial cell Neuron Fibroblast

Cerebellar peduncular complex Midbrain Midbrain tectum

13th week post-fertilization stage 15th week post-fertilization stage 12th week post-fertilization stage Carnegie stage 20 9th week post-fertilization stage 10th week post-fertilization stage Carnegie stage 16 Carnegie stage 15

Normal

10x 3' v3 10x 3' v2

Cell

Homo sapiens

T cell Natural killer cell Erythrocyte Gamma-delta t cell Cd8-alpha-alpha-positive, alpha-beta intraepithelial t cell Endothelial cell Alpha-beta t cell Mast cell Cd8-positive, alpha-beta t cell Cortical thymic epithelial cell Double-positive, alpha-beta thymocyte Plasmacytoid dendritic cell Precursor b cell Lymphocyte Cd8-positive, alpha-beta memory t cell Group 3 innate lymphoid cell Macrophage Memory b cell Regulatory t cell Plasma cell Cd4-positive, alpha-beta t cell Megakaryocyte Cd4-positive, alpha-beta memory t cell Medullary thymic epithelial cell Progenitor cell Monocyte Early t lineage precursor Vascular associated smooth muscle cell Naive b cell Double negative thymocyte Epithelial cell of thymus Fibroblast Dendritic cell

Thymus

13th week post-fertilization stage 2-year-old stage 3-month-old stage 15th week post-fertilization stage 17th week post-fertilization stage 15-month-old stage 12th week post-fertilization stage Third decade stage 16th week post-fertilization stage 9th week post-fertilization stage 6-month-old stage 10th week post-fertilization stage Organogenesis stage 10-month-old stage Fourth decade stage 11th week post-fertilization stage Juvenile stage (5-14 yo)

Normal

Female Male

10x 5' v1 10x 3' v3 10x 3' v2

Cell

Homo sapiens

Conjunctival epithelial cell Epithelial cell

Cornea Corneal epithelium Corneo-scleral junction Ocular surface region Sclera Substantia propria of cornea Tunica fibrosa of eyeball

69-year-old stage 75-year-old stage 13-year-old stage 34-year-old stage 65-year-old stage 43-year-old stage 87-year-old stage 53-year-old stage 61-year-old stage 2-year-old stage 48-year-old stage 39-year-old stage 55-year-old stage 84-year-old stage 51-year-old stage 72-year-old stage 74-year-old stage 16-year-old stage 25-year-old stage 67-year-old stage 90 year-old and over stage 32-year-old stage 77-year-old stage 33-year-old stage 64-year-old stage Postnatal stage 45-year-old stage 62-year-old stage 86-year-old stage 41-year-old stage 70-year-old stage 1-year-old stage 22-year-old stage Newborn stage (0-28 days) Eighth decade stage 83-year-old stage 11-year-old stage 27-year-old stage 10-year-old stage

Normal

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Germinal center b cell Igm plasma cell Pro-b cell Iga plasma cell Igg plasma cell Precursor b cell Memory b cell Plasmablast Naive b cell

Ascending colon Body of stomach Buccal mucosa Caecum Colon Colonic epithelium Colonic mucosa Descending colon Duodenal epithelium Duodenum Epithelium of esophagus Epithelium of rectum Epithelium of small intestine Epithelium of stomach Esophagus Gingiva Ileal epithelium Ileum Ileum lamina propria Intestine Jejunum Labial gland Lamina propria of mucosa of colon Mesenteric lymph node Parotid gland Periodontium Pyloric antrum Pylorus Rectosigmoid junction Rectum Sigmoid colon Small intestine Stomach Transverse colon Vermiform appendix

66-year-old stage 69-year-old stage 37-year-old stage 75-year-old stage Pediatric stage 19th week post-fertilization stage 21-year-old stage 13-year-old stage 34-year-old stage 65-year-old stage 26-year-old stage 43-year-old stage Sixth decade stage 13th week post-fertilization stage 85-year-old stage 61-year-old stage 2-year-old stage 52-year-old stage 54-year-old stage 68-year-old stage 48-year-old stage 30-year-old stage 39-year-old stage 44-year-old stage 29-year-old stage 56-year-old stage Fifth decade stage 55-year-old stage 84-year-old stage 15th week post-fertilization stage 50-year-old stage 80-year-old stage 28-year-old stage 51-year-old stage 17th week post-fertilization stage 57-year-old stage 12-year-old stage 72-year-old stage 12th week post-fertilization stage Third decade stage 16th week post-fertilization stage 81-year-old stage 9th week post-fertilization stage 74-year-old stage 9-year-old stage 10th week post-fertilization stage 14-year-old stage 24-year-old stage 23-year-old stage 35-year-old stage Seventh decade stage 58-year-old stage 59-year-old stage Adult stage 67-year-old stage 18th week post-fertilization stage 2-month-old stage 32-year-old stage 77-year-old stage 33-year-old stage 45-year-old stage 62-year-old stage 86-year-old stage 41-year-old stage 70-year-old stage 46-year-old stage 60-year-old stage 31-year-old stage Fourth decade stage Newborn stage (0-28 days) 63-year-old stage Eighth decade stage 76-year-old stage Prime adult stage 5-year-old stage 11-year-old stage 6-year-old stage Young adult stage 10-year-old stage 4-year-old stage 11th week post-fertilization stage Juvenile stage (5-14 yo)

Gastric cancer Inflammatory bowel disease Colorectal cancer Ulcerative colitis Normal Crohn disease

Female Male

10x 3' v1 10x 5' v2 10x 5' transcription profiling 10x 5' v1 10x 3' v3 10x 3' v2

Cell