Homo sapiens

Vascular leptomeningeal cell

Dorsolateral prefrontal cortex

69-year-old stage 75-year-old stage 42-year-old stage 89-year-old stage 87-year-old stage 85-year-old stage 88-year-old stage 68-year-old stage 29-year-old stage 84-year-old stage 82-year-old stage 50-year-old stage 80-year-old stage 72-year-old stage 81-year-old stage 80 year-old and over stage 77-year-old stage 86-year-old stage 70-year-old stage 78-year-old stage 83-year-old stage

Normal Dementia

Female Male

10x multiome 10x 3' v3

Nucleus

Mus musculus

Granulosa cell Blood vessel endothelial cell Stromal cell Endothelial cell of lymphatic vessel Cumulus granulosa cell Smooth muscle cell Steroidogenic stromal cell of ovary Endothelial cell of vascular tree Ovarian surface epithelial cell Adipocyte Macrophage Oviduct secretory cell Oocyte Late luteal cell Atretic granulosa cell Early luteal cell Theca cell Ovarian fibroblast Mural granulosa cell

Ovary

9-month-old stage

Normal

Female

Slide-seqv2

Mus musculus

Cardiac valve cell Spinal cord interneuron Premigratory neural crest cell Paraxial cell Neuroplacodal cell Hemangioblast Mesodermal cell Gut endothelial cell Primitive red blood cell Splanchnic mesodermal cell Surface ectodermal cell Midbrain dopaminergic neuron Endodermal cell

Embryo

Theiler stage 14

Normal

Slide-seqv2

Homo sapiens

Mature nk t cell Platelet Myeloid cell Plasma cell B cell Dendritic cell

Blood

74-year-old stage

Covid-19

Female

10x 3' v3

Cell

Macaca mulatta

Glutamatergic neuron

Primary motor cortex

Post-juvenile adult stage

Normal

10x 3' v3

Nucleus

Homo sapiens

Neutrophil Mature nk t cell Platelet Myeloid cell Plasma cell B cell Dendritic cell

Blood

66-year-old stage

Covid-19

Female

10x 3' v3

Cell

Homo sapiens

T cell Natural killer cell Cd8-positive, alpha-beta t cell Group 2 innate lymphoid cell Group 3 innate lymphoid cell Thymocyte T-helper 17 cell Cd16-positive, cd56-dim natural killer cell, human Regulatory t cell Type ii nk t cell Type i nk t cell Cd4-positive, alpha-beta memory t cell Cd16-negative, cd56-bright natural killer cell, human Cd34-positive, cd56-positive, cd117-positive common innate lymphoid precursor, human

Lung

Carnegie stage 19 15th week post-fertilization stage 20th week post-fertilization stage 9th week post-fertilization stage 18th week post-fertilization stage 22nd week post-fertilization stage 11th week post-fertilization stage

Normal

Female Male

10x 5' v1

Cell

Homo sapiens

Mature nk t cell Platelet Myeloid cell Plasma cell B cell Dendritic cell

Blood

74-year-old stage

Covid-19

Female

10x 3' v3

Cell

Mus musculus

Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Smooth muscle cell Microglial cell Leptomeningeal cell Pericyte Astrocyte

Primary motor cortex

Prime adult stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

T cell Hepatocyte Endothelial cell Mature nk t cell Macrophage Malignant cell B cell Monocyte Fibroblast

Liver

57-year-old stage

Breast cancer

Female

10x 3' v2

Cell

Mus musculus

Cardiac valve cell Spinal cord interneuron Premigratory neural crest cell Paraxial cell Notochordal cell Neuroplacodal cell Neurectodermal cell Hemangioblast Mesodermal cell Gut endothelial cell Primitive red blood cell Splanchnic mesodermal cell Surface ectodermal cell Midbrain dopaminergic neuron Endodermal cell Anterior visceral endoderm cell

Embryo

Theiler stage 14

Normal

Slide-seqv2

Homo sapiens

Committed oligodendrocyte precursor

Subthalamic nucleus Medial geniculate body Brodmann (1909) area 25 Lateral amygdaloid nucleus Anterior nuclear group Corticomedial nuclear complex Pontine reticular formation Temporal fusiform gyrus Brodmann (1909) area 19 Centromedian nucleus of thalamus Intralaminar nuclear group Medial dorsal nucleus of thalamus Parabrachial nucleus Primary visual cortex Claustrum of brain Inferior temporal gyrus Rostral ca3 Nucleus of medulla oblongata Red nucleus Subicular complex Pontine tegmentum Pontine nuclear group Globus pallidus Midbrain nucleus Piriform cortex Hippocampal field Lateral nuclear group of thalamus Brodmann (1909) area 13 Middle temporal gyrus Central amygdaloid nucleus Ventral anterior nucleus of thalamus Septal nuclear complex Brodmann (1909) area 35 Cerebellar nuclear complex Median tuberal portion Extrastriate cortex Epithalamus Dorsal tegmental nucleus Brodmann (1909) area 38 Lateral entorhinal cortex Supraoptic nucleus Brodmann (1909) area 32 Medial entorhinal cortex Midbrain tectum Inferior olivary complex Brodmann (1909) area 40 Inferior frontal gyrus Substantia nigra Agranular insular cortex Brodmann (1909) area 43 Nucleus accumbens Cerebrocerebellum Gray matter of midbrain Substantia innominata Anterior cortical amygdaloid nucleus Primary somatosensory cortex Brodmann (1909) area 14 Anterior olfactory nucleus Accessory basal amygdaloid nucleus Pulvinar nucleus Primary auditory cortex Hypothalamus Brodmann (1909) area 23 Primary motor cortex Brodmann (1909) area 24 Brodmann (1909) area 46 Medial zone of hypothalamus Posterior parahippocampal gyrus Basolateral amygdaloid nuclear complex Perirhinal cortex Granular insular cortex Cerebellar vermis Spinal cord Retrosplenial region Cuneus cortex Dentate gyrus of hippocampal formation Lateral posterior nucleus of thalamus Mammillary body Superior temporal gyrus Body of caudate nucleus Uncal ca1 Bed nucleus of stria terminalis Superior parietal cortex Lateral geniculate body Putamen Pretectal region Nucleus of dorsal thalamus Preoptic area

42-year-old stage 29-year-old stage 50-year-old stage 60-year-old stage

Normal

Female Male

10x 3' v3

Nucleus