Homo sapiens

Radial glial cell Oligodendrocyte Neuroblast (sensu vertebrata) Neuroblast (sensu nematoda and protostomia) Neuron Glioblast

Upper layers of the cortex Entorhinal cortex Caudate-putamen Hippocampal formation Forebrain Telencephalon Choroid plexus epithelium Frontal cortex Striatum Lower layers of the cortex Cortex Occipital cortex

9th week post-fertilization stage 13th week post-fertilization stage 12th week post-fertilization stage 10th week post-fertilization stage 11th week post-fertilization stage 15th week post-fertilization stage 14th week post-fertilization stage Carnegie stage 20

Normal

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Off parasol ganglion cell On midget ganglion cell On parasol ganglion cell Retinal ganglion cell Off midget ganglion cell

Macula lutea Peripheral region of retina Fovea centralis Macula lutea proper

80-year-old stage 85-year-old stage 82-year-old stage 66-year-old stage 16-year-old stage 70-year-old stage 18-year-old stage 77-year-old stage 21-year-old stage 32-year-old stage 50-year-old stage 86-year-old stage 76-year-old stage 62-year-old stage Prime adult stage 46-year-old stage 52-year-old stage 60-year-old stage 60-79 year-old stage 80 year-old and over stage 64-year-old stage 25-year-old stage 74-year-old stage 65-year-old stage 67-year-old stage Eighth decade stage 75-year-old stage 27-year-old stage 71-year-old stage 78-year-old stage 63-year-old stage 47-year-old stage 58-year-old stage 68-year-old stage 15-year-old stage 34-year-old stage 53-year-old stage 10-year-old stage 17-year-old stage 72-year-old stage 73-year-old stage 30-year-old stage 24-year-old stage 3-year-old stage 88-year-old stage 84-year-old stage 69-year-old stage 43-year-old stage 90 year-old and over stage Late adult stage 41-year-old stage 81-year-old stage 83-year-old stage 11-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Kidney cell Schwann cell Macrophage Neuroblast (sensu vertebrata) Fibroblast Hepatocyte Endothelial cell B cell Cortical cell of adrenal gland Dendritic cell T cell

Neck Adrenal gland Liver Cervical lymph node Chest Abdomen Lymph node

6-month-old stage 15-month-old stage 16-month-old stage 20-month-old stage 2-year-old stage 12-month-old stage 21-month-old stage 13-year-old stage 3-year-old stage 12-year-old stage 7-year-old stage 4-year-old stage 18-month-old stage 5-year-old stage

Neuroblastoma

Female Male

10x 3' v3

Nucleus

Macaca mulatta

Gabaergic neuron

Cerebellar vermis Entorhinal cortex Brodmann (1909) area 19 Inferior temporal gyrus Hippocampal formation Cerebrocerebellum Lateral geniculate body Primary somatosensory cortex Perirhinal cortex Corpus callosum Anterior cingulate cortex Primary auditory cortex Dorsolateral prefrontal cortex Pons Primary motor cortex Superior temporal sulcus Midbrain Amygdala Primary visual cortex Superior parietal cortex Medulla oblongata Inferior parietal cortex Ventral lateral nucleus of thalamus Medial dorsal nucleus of thalamus Nucleus accumbens Head of caudate nucleus Prefrontal cortex

Prime adult stage Juvenile stage

Normal

Female Male

Sci-rna-seq3

Nucleus

Macaca mulatta

Cerebellar neuron

Cerebellar vermis Entorhinal cortex Brodmann (1909) area 19 Inferior temporal gyrus Hippocampal formation Cerebrocerebellum Lateral geniculate body Primary somatosensory cortex Perirhinal cortex Corpus callosum Anterior cingulate cortex Primary auditory cortex Dorsolateral prefrontal cortex Pons Primary motor cortex Superior temporal sulcus Midbrain Amygdala Primary visual cortex Superior parietal cortex Medulla oblongata Inferior parietal cortex Ventral lateral nucleus of thalamus Medial dorsal nucleus of thalamus Nucleus accumbens Head of caudate nucleus Prefrontal cortex

Prime adult stage Juvenile stage

Normal

Female Male

Sci-rna-seq3

Nucleus

Homo sapiens

Myofibroblast cell Schwann cell Capillary endothelial cell Colonocyte Igg plasma cell Colon goblet cell Endothelial cell of lymphatic vessel Cd4-positive, alpha-beta t cell Iga plasma cell Macrophage Mature b cell Effector cd8-positive, alpha-beta t cell Glandular secretory epithelial cell Mast cell Endothelial tip cell Endothelial cell of venule Stem cell Monocyte Enteroendocrine cell Tuft cell of colon Granulocyte Cd8-positive, alpha-beta memory t cell Conventional dendritic cell Fibroblast Group 3 innate lymphoid cell T-helper 17 cell Pericyte Cd8-positive, alpha-beta t cell Cd4-positive, cd25-positive, alpha-beta regulatory t cell Activated cd4-positive, alpha-beta t cell Dendritic cell Mature nk t cell T cell Colon endothelial cell Plasmacytoid dendritic cell Enterocyte Intestinal epithelial cell T follicular helper cell Smooth muscle cell Natural killer cell Endothelial cell of artery Gamma-delta t cell Mature conventional dendritic cell Germinal center b cell Goblet cell

Colorectum

91-year-old stage 82-year-old stage 70-year-old stage 77-year-old stage 50-year-old stage 57-year-old stage 76-year-old stage 62-year-old stage 52-year-old stage 60-year-old stage 48-year-old stage 64-year-old stage 89-year-old stage 45-year-old stage 67-year-old stage 71-year-old stage 78-year-old stage 36-year-old stage 59-year-old stage 47-year-old stage 56-year-old stage 58-year-old stage 61-year-old stage 51-year-old stage 49-year-old stage 42-year-old stage 35-year-old stage 53-year-old stage 72-year-old stage 73-year-old stage 84-year-old stage 90-year-old stage 69-year-old stage 81-year-old stage 55-year-old stage

Normal Colon adenocarcinoma

Female Male

10x 3' v3 10x 3' v2

Cell

Mus musculus

Kidney loop of henle thick ascending limb epithelial cell Kidney cell Immature t cell Bladder cell Circulating fibrocyte Smooth muscle cell of the pulmonary artery Kupffer cell Cardiac neuron Promonocyte Schwann cell Pulmonary interstitial fibroblast Pancreatic ductal cell Pulmonary alveolar type 1 cell Epithelial cell of thymus Naive b cell Endothelial cell of hepatic sinusoid Mesenchymal stem cell Classical monocyte Astrocyte Oligodendrocyte precursor cell Cardiac muscle cell Endothelial cell of lymphatic vessel Endothelial cell of coronary artery Kidney loop of henle ascending limb epithelial cell Dn3 thymocyte Oligodendrocyte Tuft cell of large intestine Cd4-positive, alpha-beta t cell Pulmonary alveolar type 2 cell Club cell Pulmonary neuroendocrine cell Neural stem cell Intestinal crypt stem cell Non-classical monocyte Leukocyte Lymphocyte Macrophage Medium spiny neuron Pancreatic acinar cell Kidney distal convoluted tubule epithelial cell Alveolar macrophage Granulocyte monocyte progenitor cell Endocardial cell Enterocyte of epithelium of large intestine Late pro-b cell Stromal cell Kidney interstitial fibroblast Dn4 thymocyte Kidney collecting duct principal cell Mast cell Basal cell Blood cell Epithelial cell Type b pancreatic cell Multiciliated columnar cell of tracheobronchial tree Megakaryocyte-erythroid progenitor cell Duct epithelial cell Macrophage dendritic cell progenitor Naive t cell Pancreatic d cell Bergmann glial cell Neutrophil Basal epithelial cell of tracheobronchial tree Monocyte Interneuron Cell of skeletal muscle Myeloid dendritic cell Enteroendocrine cell Basal cell of epidermis Granulocytopoietic cell Keratinocyte stem cell Luminal epithelial cell of mammary gland Immature b cell Lymphoid lineage restricted progenitor cell Double negative thymocyte Tuft cell Epithelial cell of proximal tubule Vein endothelial cell Microglial cell Granulocyte Neuroepithelial stem cell Bladder urothelial cell Regular atrial cardiac myocyte Fibroblast Mature alpha-beta t cell Brain pericyte Hepatocyte Hematopoietic precursor cell Hematopoietic stem cell Ependymal cell Pericyte Endothelial cell Skeletal muscle satellite cell Myeloid leukocyte Regular ventricular cardiac myocyte Erythroid progenitor cell, mammalian Pancreatic stellate cell Pancreatic pp cell Adventitial cell Mesenchymal cell Pancreatic a cell Intermediate monocyte Erythroblast B cell Thymocyte Cardiac valve cell Epidermal cell Kidney capillary endothelial cell Immature nk t cell Cd8-positive, alpha-beta t cell Lung macrophage Hepatic stellate cell Bronchial smooth muscle cell Kidney proximal straight tubule epithelial cell Dendritic cell Plasma cell Mesangial cell Erythrocyte Regulatory t cell Fibroblast of cardiac tissue Mature nk t cell T cell Mesenchymal stem cell of adipose tissue Plasmacytoid dendritic cell Smooth muscle cell of trachea Secretory cell Precursor b cell Mucus secreting cell Neuroendocrine cell Fenestrated endothelial cell Kidney proximal convoluted tubule epithelial cell Stem cell of epidermis Kidney collecting duct epithelial cell Fibroblast of lung Early pro-b cell Smooth muscle cell Basophil Proerythroblast Respiratory basal cell Neuron Plasmatocyte Large intestine goblet cell Epithelial cell of large intestine Keratinocyte Natural killer cell Chondrocyte Kidney cortex artery cell Professional antigen presenting cell Aortic endothelial cell Langerhans cell Myeloid cell

Thymus Liver Spleen Brown adipose tissue Lung Gonadal fat pad Mesenteric fat pad Trachea Mammary gland Kidney Pancreas Aorta Brain Adipose tissue Tongue Subcutaneous adipose tissue Diaphragm Limb muscle Bone marrow Skin of body Bladder lumen Heart Large intestine

3-month-old stage 20-month-old stage and over 18-month-old stage 4-week-old stage

Normal

Female Male

Smart-seq2 10x 3' v2

Cell

Homo sapiens

Myofibroblast cell Epithelial cell of thymus Cd4-positive, alpha-beta t cell Lymphocyte Macrophage Effector cd8-positive, alpha-beta t cell Mast cell Cd8-positive, cd28-negative, alpha-beta regulatory t cell Naive t cell Monocyte Microglial cell Fibroblast Malignant cell Naive thymus-derived cd8-positive, alpha-beta t cell T-helper 17 cell Endothelial cell Central memory cd8-positive, alpha-beta t cell B cell Cd8-positive, alpha-beta t cell Plasmacytoid dendritic cell, human Dendritic cell Plasma cell Regulatory t cell Mature nk t cell T cell Activated cd8-positive, alpha-beta t cell, human T follicular helper cell Hematopoietic multipotent progenitor cell Melanocyte Myeloid cell

Arm skin Skin of forehead Breast Skin of cheek Skin of calf Liver Skin of external ear Nose skin Kidney Brain Skin of scalp Skin of knee Skin of neck Skin of body

80-year-old stage 85-year-old stage 79-year-old stage Fourth decade stage 77-year-old stage 86-year-old stage 57-year-old stage 76-year-old stage 62-year-old stage Prime adult stage 52-year-old stage 60-year-old stage 60-79 year-old stage 80 year-old and over stage 64-year-old stage 74-year-old stage 65-year-old stage 67-year-old stage Middle aged stage Postnatal stage Eighth decade stage 37-year-old stage 71-year-old stage Adult stage 63-year-old stage 54-year-old stage Fifth decade stage 47-year-old stage 58-year-old stage 68-year-old stage 61-year-old stage 72-year-old stage 73-year-old stage Seventh decade stage 69-year-old stage 43-year-old stage Late adult stage 41-year-old stage 81-year-old stage 83-year-old stage Sixth decade stage

Melanoma Her2 positive breast carcinoma Triple-negative breast carcinoma Metastatic melanoma Hepatocellular carcinoma Squamous cell carcinoma Estrogen-receptor positive breast cancer Basal cell carcinoma Intrahepatic cholangiocarcinoma Nonpapillary renal cell carcinoma

Female Male

Smart-seq2 10x 3' v3 10x 5' transcription profiling 10x 3' v2

Cell

Homo sapiens

Schwann cell Colon epithelial cell Mesothelial cell Stromal cell Interstitial cell of cajal Basal cell Mesodermal cell Epithelial cell Paneth cell Stem cell Enteroendocrine cell Hematopoietic cell Intestinal tuft cell Pericyte Endothelial cell Colon endothelial cell Enterocyte Smooth muscle cell Neuron Ciliated cell M cell of gut Goblet cell

Ileum Duodenum Colon Intestine

Normal

10x 5' v2 10x 3' v3 Sort-seq Seq-well s3 10x 3' v2

Cell Nucleus

Homo sapiens

Luminal hormone-sensing cell of mammary gland Luminal adaptive secretory precursor cell of mammary gland Basal-myoepithelial cell of mammary gland Mammary gland epithelial cell

Breast

19-year-old stage 21-year-old stage 57-year-old stage 62-year-old stage 46-year-old stage 52-year-old stage 48-year-old stage 45-year-old stage 25-year-old stage 33-year-old stage 65-year-old stage 40-year-old stage 27-year-old stage 23-year-old stage 37-year-old stage 28-year-old stage 36-year-old stage 63-year-old stage 59-year-old stage 20-year-old stage 31-year-old stage 56-year-old stage 58-year-old stage 34-year-old stage 35-year-old stage 53-year-old stage 30-year-old stage 24-year-old stage 39-year-old stage 29-year-old stage 38-year-old stage 41-year-old stage 55-year-old stage

Normal

Female

10x 3' v3

Cell

Homo sapiens

Kidney loop of henle thick ascending limb epithelial cell Cd8-alpha-negative thymic conventional dendritic cell Classical monocyte Kidney connecting tubule epithelial cell Parietal epithelial cell Non-classical monocyte Naive regulatory t cell Macrophage Naive thymus-derived cd4-positive, alpha-beta t cell Kidney distal convoluted tubule epithelial cell Mucosal invariant t cell Kidney interstitial fibroblast Kidney collecting duct principal cell Mast cell Kidney loop of henle thin descending limb epithelial cell Renal interstitial pericyte Migratory dendritic cell Cycling macrophage Kidney resident macrophage Epithelial cell of proximal tubule Kidney collecting duct intercalated cell Group 3 innate lymphoid cell Podocyte Effector memory cd8-positive, alpha-beta t cell Endothelial cell B cell Plasmacytoid dendritic cell, human Plasma cell Effector memory cd8-positive, alpha-beta t cell, terminally differentiated Natural killer cell Cd8-alpha-positive thymic conventional dendritic cell Neural cell Kidney loop of henle thin ascending limb epithelial cell

Kidney

66-year-old stage Fourth decade stage 57-year-old stage 52-year-old stage 48-year-old stage 40-year-old stage Eighth decade stage Ninth decade stage Fifth decade stage 47-year-old stage 31-year-old stage 56-year-old stage 49-year-old stage 42-year-old stage 35-year-old stage 30-year-old stage Seventh decade stage 39-year-old stage Third decade stage 41-year-old stage Sixth decade stage

Normal Chronic kidney disease Acute kidney failure

Female Male

10x 3' v3

Cell

Homo sapiens

Myoepithelial cell Pulmonary alveolar type 1 cell Endothelial cell of respiratory system lymphatic vessel Classical monocyte Lung megakaryocyte Innate lymphoid cell Alveolar capillary type 2 endothelial cell Pulmonary alveolar type 2 cell Pulmonary neuroendocrine cell Non-classical monocyte Ionocyte Helper t cell Vein endothelial cell of respiratory system Alveolar macrophage Brush cell of tracheobronchial tree Mucus secreting cell of tracheobronchial tree submucosal gland Alveolar type 1 fibroblast cell Mast cell Tracheobronchial smooth muscle cell Basal cell Lung interstitial macrophage Neutrophil Cd8-positive, alpha-beta cytotoxic t cell Vein endothelial cell Serous secreting cell Vascular associated smooth muscle cell Conventional dendritic cell Alveolar capillary type 1 endothelial cell Pericyte Secondary crest myofibroblast Deuterosomal cell Airway submucosal gland collecting duct epithelial cell Mesothelial cell of pleura B cell Plasma cell Regulatory t cell Plasmacytoid dendritic cell Secretory cell Alveolar adventitial fibroblast Lung secretory cell Natural killer cell Chondrocyte Endothelial cell of artery Ciliated cell Mature conventional dendritic cell Goblet cell Respiratory tract suprabasal cell

Lung

80-year-old stage 66-year-old stage 79-year-old stage 70-year-old stage 21-year-old stage 32-year-old stage 50-year-old stage 57-year-old stage 76-year-old stage 62-year-old stage 46-year-old stage 52-year-old stage 22-year-old stage 44-year-old stage 48-year-old stage 64-year-old stage 45-year-old stage 25-year-old stage 33-year-old stage 65-year-old stage 67-year-old stage 40-year-old stage 75-year-old stage 27-year-old stage 23-year-old stage 37-year-old stage 36-year-old stage 63-year-old stage 59-year-old stage 54-year-old stage 20-year-old stage 47-year-old stage 31-year-old stage 56-year-old stage 68-year-old stage 61-year-old stage 51-year-old stage 49-year-old stage 42-year-old stage 35-year-old stage 10-year-old stage 17-year-old stage 72-year-old stage 30-year-old stage 24-year-old stage 13-year-old stage 26-year-old stage 12-year-old stage 39-year-old stage 69-year-old stage 29-year-old stage 38-year-old stage 41-year-old stage 55-year-old stage

Normal

Female Male

10x 5' v1 10x 3' v3 10x 3' v2

Cell