Homo sapiens

Natural killer cell Gamma-delta t cell Cd8-positive, alpha-beta t cell Mature nk t cell, human Lymphocyte Naive thymus-derived cd8-positive, alpha-beta t cell Memory b cell Cd16-positive, cd56-dim natural killer cell, human Regulatory t cell Plasmablast Plasma cell Cd4-positive, alpha-beta memory t cell Naive thymus-derived cd4-positive, alpha-beta t cell Mucosal invariant t cell Naive b cell Cd16-negative, cd56-bright natural killer cell, human

Blood

37-year-old stage 21-year-old stage 34-year-old stage 42-year-old stage 26-year-old stage 43-year-old stage 53-year-old stage 52-year-old stage 54-year-old stage 48-year-old stage 30-year-old stage 39-year-old stage 44-year-old stage 29-year-old stage 38-year-old stage 55-year-old stage 50-year-old stage 28-year-old stage 51-year-old stage 57-year-old stage 49-year-old stage 24-year-old stage 23-year-old stage 35-year-old stage 58-year-old stage 25-year-old stage 32-year-old stage 33-year-old stage 45-year-old stage 41-year-old stage 46-year-old stage 60-year-old stage 18-year-old stage 31-year-old stage 36-year-old stage 22-year-old stage 19-year-old stage 20-year-old stage 47-year-old stage 27-year-old stage 40-year-old stage

Normal

Female Male

10x 5' v2

Cell

Mus musculus

Glutamatergic neuron

Secondary somatosensory cortex Lateral septal complex Piriform cortex Hippocampal field Pallidum Orbitofrontal cortex Olfactory cortex Cerebral cortex Nucleus accumbens Primary somatosensory cortex Anterior olfactory nucleus Primary auditory cortex Primary motor cortex Caudate-putamen Dentate gyrus of hippocampal formation Anterior cerebral artery

Prime adult stage

Normal

Male

Scatac-seq

Nucleus

Mus musculus

Erythrocyte Oligodendrocyte precursor cell Endothelial cell Hypendymal cell Oligodendrocyte Tanycyte Ependymal cell Microglial cell Mural cell Pituitary gland cell Neuron Astrocyte Fibroblast

Hypothalamus

9-week-old stage Juvenile stage 4-week-old stage 23-day-old stage 2-week-old stage 1-week-old stage 6-week-old stage 26-day-old stage 2-month-old stage 8-week-old stage

Normal

Female Male

10x 3' v1 10x 3' v3 Drop-seq 10x 3' v2

Nucleus Cell

Mus musculus

T cell Cell Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Vascular leptomeningeal cell Inhibitory interneuron Macrophage Microglial cell Pericyte Neuron Astrocyte Medium spiny neuron

Striatum Cortical layer v Cortical layer vi Olfactory region Cortical layer ii/iii Corpus callosum Brain ventricle Pia mater

4-week-old stage 24-week-old stage 20-month-old stage and over

Normal

Female

Merfish

Mus musculus

T cell Cell Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Vascular leptomeningeal cell Inhibitory interneuron Macrophage Microglial cell Pericyte Neuron Astrocyte Medium spiny neuron

Striatum Cortical layer v Cortical layer vi Olfactory region Cortical layer ii/iii Corpus callosum Brain ventricle Pia mater

4-week-old stage 24-week-old stage 20-month-old stage and over

Normal

Female

Merfish

Homo sapiens

Glioblast Oligodendrocyte Neuroblast (sensu nematoda and protostomia) Neuroblast (sensu vertebrata) Radial glial cell Neuron

Choroid plexus epithelium Striatum Telencephalon Cortex Lower layers of the cortex Frontal cortex Entorhinal cortex Upper layers of the cortex Caudate-putamen Hippocampal formation Occipital cortex Forebrain

13th week post-fertilization stage 14th week post-fertilization stage 15th week post-fertilization stage 12th week post-fertilization stage Carnegie stage 20 9th week post-fertilization stage 10th week post-fertilization stage 11th week post-fertilization stage

Normal

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Off midget ganglion cell Retinal ganglion cell Off parasol ganglion cell On midget ganglion cell On parasol ganglion cell

Peripheral region of retina Macula lutea proper Fovea centralis Macula lutea

66-year-old stage 69-year-old stage 75-year-old stage 21-year-old stage 34-year-old stage 65-year-old stage 43-year-old stage 71-year-old stage 85-year-old stage 53-year-old stage 88-year-old stage 52-year-old stage 68-year-old stage 30-year-old stage 17-year-old stage 84-year-old stage 15-year-old stage 82-year-old stage 50-year-old stage 80-year-old stage 72-year-old stage 81-year-old stage 74-year-old stage 80 year-old and over stage 24-year-old stage 16-year-old stage 58-year-old stage 25-year-old stage 67-year-old stage Late adult stage 90 year-old and over stage 3-year-old stage 32-year-old stage 77-year-old stage 64-year-old stage 62-year-old stage 86-year-old stage 41-year-old stage 70-year-old stage 46-year-old stage 60-year-old stage 78-year-old stage 18-year-old stage 60-79 year-old stage 63-year-old stage Eighth decade stage 47-year-old stage 76-year-old stage 73-year-old stage 83-year-old stage Prime adult stage 11-year-old stage 27-year-old stage 10-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Kidney cell T cell Hepatocyte Endothelial cell Cortical cell of adrenal gland Schwann cell Macrophage Neuroblast (sensu vertebrata) B cell Fibroblast Dendritic cell

Neck Liver Abdomen Chest Adrenal gland Lymph node Cervical lymph node

13-year-old stage 2-year-old stage 12-year-old stage 15-month-old stage 6-month-old stage 21-month-old stage 20-month-old stage 3-year-old stage 16-month-old stage 18-month-old stage 5-year-old stage 12-month-old stage 7-year-old stage 4-year-old stage

Neuroblastoma

Female Male

10x 3' v3

Nucleus

Macaca mulatta

Gabaergic neuron

Dorsolateral prefrontal cortex Brodmann (1909) area 19 Medial dorsal nucleus of thalamus Primary visual cortex Ventral lateral nucleus of thalamus Inferior temporal gyrus Medulla oblongata Prefrontal cortex Midbrain Entorhinal cortex Nucleus accumbens Cerebrocerebellum Primary somatosensory cortex Primary auditory cortex Primary motor cortex Inferior parietal cortex Head of caudate nucleus Corpus callosum Hippocampal formation Perirhinal cortex Pons Cerebellar vermis Anterior cingulate cortex Superior temporal sulcus Superior parietal cortex Lateral geniculate body Amygdala

Juvenile stage Prime adult stage

Normal

Female Male

Sci-rna-seq3

Nucleus

Macaca mulatta

Cerebellar neuron

Dorsolateral prefrontal cortex Brodmann (1909) area 19 Medial dorsal nucleus of thalamus Primary visual cortex Ventral lateral nucleus of thalamus Inferior temporal gyrus Medulla oblongata Prefrontal cortex Midbrain Entorhinal cortex Nucleus accumbens Cerebrocerebellum Primary somatosensory cortex Primary auditory cortex Primary motor cortex Inferior parietal cortex Head of caudate nucleus Corpus callosum Hippocampal formation Perirhinal cortex Pons Cerebellar vermis Anterior cingulate cortex Superior temporal sulcus Superior parietal cortex Lateral geniculate body Amygdala

Juvenile stage Prime adult stage

Normal

Female Male

Sci-rna-seq3

Nucleus

Homo sapiens

T cell Effector cd8-positive, alpha-beta t cell Germinal center b cell Granulocyte Endothelial tip cell Mature conventional dendritic cell Endothelial cell of venule Natural killer cell Endothelial cell of lymphatic vessel Gamma-delta t cell Activated cd4-positive, alpha-beta t cell Mature nk t cell Colon endothelial cell Mast cell Cd8-positive, alpha-beta t cell Iga plasma cell Stem cell Endothelial cell of artery Capillary endothelial cell Schwann cell Smooth muscle cell Plasmacytoid dendritic cell Igg plasma cell Enteroendocrine cell Cd8-positive, alpha-beta memory t cell Group 3 innate lymphoid cell Goblet cell T-helper 17 cell Macrophage Tuft cell of colon Cd4-positive, cd25-positive, alpha-beta regulatory t cell Mature b cell Enterocyte Intestinal epithelial cell Cd4-positive, alpha-beta t cell Glandular secretory epithelial cell T follicular helper cell Colon goblet cell Pericyte Monocyte Myofibroblast cell Conventional dendritic cell Fibroblast Colonocyte Dendritic cell

Colorectum

69-year-old stage 91-year-old stage 42-year-old stage 89-year-old stage 71-year-old stage 53-year-old stage 61-year-old stage 52-year-old stage 48-year-old stage 56-year-old stage 55-year-old stage 84-year-old stage 82-year-old stage 50-year-old stage 90-year-old stage 51-year-old stage 57-year-old stage 72-year-old stage 81-year-old stage 49-year-old stage 35-year-old stage 58-year-old stage 59-year-old stage 67-year-old stage 77-year-old stage 64-year-old stage 45-year-old stage 62-year-old stage 70-year-old stage 60-year-old stage 78-year-old stage 36-year-old stage 47-year-old stage 76-year-old stage 73-year-old stage

Normal Colon adenocarcinoma

Female Male

10x 3' v3 10x 3' v2

Cell

Mus musculus

Endothelial cell of hepatic sinusoid Kidney cell T cell Neutrophil Bladder urothelial cell Endocardial cell Club cell Granulocyte Tuft cell of large intestine Neural stem cell Hepatocyte Stromal cell Immature t cell Natural killer cell Endothelial cell of lymphatic vessel Erythrocyte Oligodendrocyte precursor cell Multiciliated columnar cell of tracheobronchial tree Mature alpha-beta t cell Secretory cell Kidney collecting duct epithelial cell Endothelial cell Kupffer cell Oligodendrocyte Cardiac valve cell Neuroendocrine cell Mature nk t cell Hematopoietic precursor cell Erythroid progenitor cell, mammalian Kidney interstitial fibroblast Mast cell Kidney cortex artery cell Cd8-positive, alpha-beta t cell Pulmonary neuroendocrine cell Pancreatic acinar cell Pancreatic pp cell Late pro-b cell Basal cell Stem cell of epidermis Luminal epithelial cell of mammary gland Bladder cell Schwann cell Leukocyte Classical monocyte Kidney capillary endothelial cell Smooth muscle cell Intermediate monocyte Epithelial cell of proximal tubule Epithelial cell Smooth muscle cell of the pulmonary artery Skeletal muscle satellite cell Dn3 thymocyte Plasmacytoid dendritic cell Cardiac neuron Precursor b cell Lymphoid lineage restricted progenitor cell Hepatic stellate cell Pancreatic a cell Myeloid dendritic cell Immature nk t cell Enteroendocrine cell Brain pericyte Plasmatocyte Lymphocyte Lung macrophage Thymocyte Basal cell of epidermis Ependymal cell Tuft cell Endothelial cell of coronary artery Macrophage Intestinal crypt stem cell Microglial cell Fenestrated endothelial cell Pancreatic d cell Kidney distal convoluted tubule epithelial cell Kidney collecting duct principal cell Regulatory t cell Macrophage dendritic cell progenitor Pulmonary alveolar type 1 cell Pancreatic stellate cell Duct epithelial cell Kidney loop of henle thick ascending limb epithelial cell Myeloid cell Bronchial smooth muscle cell Respiratory basal cell Promonocyte Fibroblast of lung Keratinocyte Hematopoietic stem cell Kidney proximal straight tubule epithelial cell Alveolar macrophage Plasma cell Cd4-positive, alpha-beta t cell Vein endothelial cell Type b pancreatic cell Mesenchymal cell Mesangial cell Langerhans cell Interneuron Aortic endothelial cell Mesenchymal stem cell of adipose tissue Granulocytopoietic cell Epidermal cell Cell of skeletal muscle Pulmonary interstitial fibroblast Bergmann glial cell Keratinocyte stem cell Cardiac muscle cell B cell Pericyte Granulocyte monocyte progenitor cell Dn4 thymocyte Professional antigen presenting cell Naive t cell Circulating fibrocyte Neuron Mesenchymal stem cell Immature b cell Megakaryocyte-erythroid progenitor cell Neuroepithelial stem cell Smooth muscle cell of trachea Myeloid leukocyte Regular atrial cardiac myocyte Adventitial cell Monocyte Mucus secreting cell Naive b cell Kidney loop of henle ascending limb epithelial cell Pancreatic ductal cell Large intestine goblet cell Enterocyte of epithelium of large intestine Double negative thymocyte Erythroblast Blood cell Proerythroblast Astrocyte Basophil Epithelial cell of large intestine Epithelial cell of thymus Kidney proximal convoluted tubule epithelial cell Regular ventricular cardiac myocyte Fibroblast Early pro-b cell Dendritic cell Fibroblast of cardiac tissue Pulmonary alveolar type 2 cell Medium spiny neuron Non-classical monocyte Basal epithelial cell of tracheobronchial tree Chondrocyte

Skin of body Lung Thymus Brown adipose tissue Gonadal fat pad Diaphragm Mesenteric fat pad Trachea Aorta Liver Subcutaneous adipose tissue Kidney Heart Tongue Mammary gland Brain Pancreas Large intestine Limb muscle Spleen Bladder lumen Bone marrow Adipose tissue

4-week-old stage 3-month-old stage 20-month-old stage and over 18-month-old stage

Normal

Female Male

Smart-seq2 10x 3' v2

Cell