Homo sapiens

T cell Central nervous system macrophage Natural killer cell Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Committed oligodendrocyte precursor Cerebellar granule cell Cerebellar inhibitory gabaergic interneuron Microglial cell Bergmann glial cell Pericyte Neuron Monocyte Intratelencephalic-projecting glutamatergic cortical neuron Purkinje cell Vascular associated smooth muscle cell Astrocyte Unipolar brush cell Fibroblast

Cerebrocerebellum

42-year-old stage 29-year-old stage 50-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Granulocyte Erythroid progenitor cell Pro-b cell Myeloid lineage restricted progenitor cell Precursor b cell Lymphoid lineage restricted progenitor cell Common dendritic progenitor Hematopoietic multipotent progenitor cell Common lymphoid progenitor Megakaryocyte-erythroid progenitor cell Erythroblast Proerythroblast

Liver Umbilical cord blood Bone marrow

Fifth lmp month stage 14th week post-fertilization stage Newborn stage (0-28 days) Fourth lmp month stage

Normal

Female

10x 3' v3

Cell

Homo sapiens

Podocyte Natural killer cell Endothelial cell of lymphatic vessel Renal beta-intercalated cell Endothelial cell Mast cell Cd8-positive, alpha-beta t cell Iga plasma cell Activated type ii nk t cell Classical monocyte Epithelial cell of proximal tubule Epithelial cell Igg plasma cell Epithelial cell of proximal tubule segment 1 Renal alpha-intercalated cell Macrophage Cd4-positive, cd25-positive, alpha-beta regulatory t cell Kidney distal convoluted tubule epithelial cell Kidney pelvis urothelial cell Kidney collecting duct principal cell Kidney connecting tubule principal cell Kidney loop of henle thick ascending limb epithelial cell Mhc-ii-positive classical monocyte Epithelial cell of proximal tubule segment 3 Cd4-positive, alpha-beta t cell B cell Pericyte Naive thymus-derived cd4-positive, alpha-beta t cell Collagen secreting cell Naive b cell Kidney loop of henle ascending limb epithelial cell Conventional dendritic cell Fibroblast Non-classical monocyte

Kidney

Sixth decade stage Fifth decade stage Seventh decade stage Eighth decade stage

Nonpapillary renal cell carcinoma

Female Male

Visium spatial gene expression v1

Mus musculus

Podocyte Endothelial cell Kidney interstitial fibroblast Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney granular cell Kidney collecting duct principal cell Kidney loop of henle thick ascending limb epithelial cell Macula densa epithelial cell Mesangial cell Kidney proximal convoluted tubule epithelial cell

Kidney

13-week-old stage

Normal

Male

Slide-seqv2

Danio rerio

Glutamatergic neuron Spinal cord interneuron Neuroblast (sensu vertebrata) Glial cell Glycinergic neuron Gabaergic neuron Neural progenitor cell

Hindbrain Multicellular anatomical structure Neural rod Spinal cord

Pharyngula:prim-15 Hatching:long-pec Larval:protruding-mouth Pharyngula:prim-25 Segmentation:26+ somites Segmentation:14-19 somites Hatching:pec-fin Segmentation:20-25 somites Pharyngula:high-pec Pharyngula:prim-5

Normal

Sci-rna-seq3

Nucleus

Homo sapiens

Cd8-positive, alpha-beta t cell Exhausted t cell Cd4-positive helper t cell Regulatory t cell Myeloid cell Plasma cell Malignant cell T follicular helper cell B cell

Lymph node

Adult stage

Metastatic melanoma

Slide-seqv2

Homo sapiens

T cell Podocyte Renal principal cell Kidney cortex collecting duct epithelial cell Natural killer cell Parietal epithelial cell Renal beta-intercalated cell Kidney loop of henle cortical thick ascending limb epithelial cell Kidney capillary endothelial cell Epithelial cell of proximal tubule Renal alpha-intercalated cell Kidney distal convoluted tubule epithelial cell Kidney connecting tubule epithelial cell Mesangial cell Kidney loop of henle descending limb epithelial cell B cell Mononuclear phagocyte

Cortex of kidney

37-year-old stage 34-year-old stage 65-year-old stage 42-year-old stage 43-year-old stage 44-year-old stage 38-year-old stage 55-year-old stage 50-year-old stage 57-year-old stage 49-year-old stage 35-year-old stage 58-year-old stage 33-year-old stage 64-year-old stage 41-year-old stage 60-year-old stage

Normal

Female Male

10x 3' v3

Cell

Homo sapiens

Adipocyte

Subcutaneous adipose tissue Visceral fat

34-year-old stage 53-year-old stage 48-year-old stage 29-year-old stage 28-year-old stage 24-year-old stage Adult stage 33-year-old stage 41-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Mus musculus

Podocyte Endothelial cell Kidney interstitial fibroblast Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney granular cell Kidney collecting duct principal cell Kidney loop of henle thick ascending limb epithelial cell Macula densa epithelial cell Mesangial cell Kidney proximal convoluted tubule epithelial cell

Kidney

13-week-old stage

Diabetic kidney disease

Male

Slide-seqv2

Homo sapiens

Erythrocyte Mast cell Plasmacytoid dendritic cell Precursor b cell Hematopoietic stem cell Megakaryocyte Progenitor cell Megakaryocyte-erythroid progenitor cell Early t lineage precursor Double negative thymocyte

Thymus Liver

Carnegie stage 19 13th week post-fertilization stage 2-year-old stage 3-month-old stage 15th week post-fertilization stage 17th week post-fertilization stage 15-month-old stage 12th week post-fertilization stage Third decade stage 16th week post-fertilization stage 9th week post-fertilization stage Carnegie stage 23 6-month-old stage 10th week post-fertilization stage Organogenesis stage 15-19 year-old 10-month-old stage Carnegie stage 22 Fourth decade stage 11th week post-fertilization stage Juvenile stage (5-14 yo)

Normal

Female Male

10x 5' v1 10x 3' v3 10x 3' v2

Cell

Danio rerio

Glutamatergic neuron Neuroblast (sensu vertebrata) Gabaergic neuron Neural progenitor cell

Midbrain-hindbrain boundary Hindbrain Midbrain Midbrain tectum Multicellular anatomical structure Brain Midbrain tegmentum

Pharyngula:prim-15 Hatching:long-pec Larval:protruding-mouth Pharyngula:prim-25 Segmentation:26+ somites Segmentation:14-19 somites Hatching:pec-fin Segmentation:20-25 somites Pharyngula:high-pec Pharyngula:prim-5

Normal

Sci-rna-seq3

Nucleus

Danio rerio

Cardiac endothelial cell Endothelial cell

Endocardium Lymphatic vessel endothelium Blood vessel endothelium

Pharyngula:prim-15 Hatching:long-pec Larval:protruding-mouth Pharyngula:prim-25 Segmentation:26+ somites Segmentation:14-19 somites Hatching:pec-fin Segmentation:20-25 somites Pharyngula:high-pec Pharyngula:prim-5

Normal

Sci-rna-seq3

Nucleus