Homo sapiens

Transit amplifying cell of small intestine Intestine goblet cell Intestinal crypt stem cell of large intestine Secretory cell Interstitial cell of cajal Erythroid lineage cell Leukocyte Gut absorptive cell Inhibitory motor neuron Plasmacytoid dendritic cell Neural cell Enteroendocrine cell Gut endothelial cell Group 3 innate lymphoid cell Transit amplifying cell of colon Macrophage Enteric smooth muscle cell Glial cell Enterocyte B cell Pericyte Progenitor cell Naive t cell Intestinal crypt stem cell of small intestine Monocyte Myofibroblast cell Fibroblast Dendritic cell

Colon

66-year-old stage

Normal

Male

Visium spatial gene expression v1

Homo sapiens

Intestine goblet cell Intestinal crypt stem cell of large intestine Secretory cell Neuroendocrine cell Interstitial cell of cajal Leukocyte Gut absorptive cell Gut endothelial cell Group 3 innate lymphoid cell Enteric smooth muscle cell Enterocyte Motor neuron Interneuron Pericyte Progenitor cell Intestinal crypt stem cell of small intestine Monocyte Myofibroblast cell Fibroblast

Ileum

13th week post-fertilization stage

Normal

Male

Visium spatial gene expression v1

Homo sapiens

Intestine goblet cell Intestinal crypt stem cell of large intestine Secretory cell Interstitial cell of cajal Leukocyte Gut absorptive cell Inhibitory motor neuron Neural cell Gut endothelial cell Transit amplifying cell of colon Enteric smooth muscle cell Glial cell Enterocyte Motor neuron Mesothelial cell Pericyte Progenitor cell Intestinal crypt stem cell of small intestine Myofibroblast cell Fibroblast

Colon

13th week post-fertilization stage

Normal

Male

Visium spatial gene expression v1

Homo sapiens

Hepatocyte Plasmacytoid dendritic cell Hepatic stellate cell Macrophage Endothelial cell of pericentral hepatic sinusoid Cholangiocyte Plasma cell Vascular associated smooth muscle cell Basophil Conventional dendritic cell Fibroblast Non-classical monocyte

Liver

68-year-old stage

Normal

Female

Visium spatial gene expression v1

Homo sapiens

Neutrophil Hepatocyte Endothelial cell of periportal hepatic sinusoid Macrophage Cholangiocyte Plasma cell Vascular associated smooth muscle cell Basophil Fibroblast

Liver

59-year-old stage

Normal

Female

Visium spatial gene expression v1

Homo sapiens

Hepatocyte Endothelial cell of periportal hepatic sinusoid Macrophage Cholangiocyte

Liver

59-year-old stage

Normal

Female

Visium spatial gene expression v1

Homo sapiens

Intestine goblet cell Intestinal crypt stem cell of large intestine Interstitial cell of cajal Leukocyte Gut absorptive cell Inhibitory motor neuron Neural cell Precursor b cell Enteroendocrine cell Gut endothelial cell Group 3 innate lymphoid cell Macrophage Enteric smooth muscle cell Glial cell Enterocyte Interneuron Mesothelial cell Pericyte Naive t cell Monocyte Myofibroblast cell Fibroblast

Colon

13th week post-fertilization stage

Normal

Female

Visium spatial gene expression v1

Mus musculus

Hepatocyte Erythrocyte Mesothelial cell Fibroblast

Capsule of liver

Young adult stage

Normal

Visium spatial gene expression v1

Mus musculus

Endothelial cell of hepatic sinusoid Neutrophil Hepatocyte Endothelial cell of periportal hepatic sinusoid Erythrocyte Kupffer cell Intermediate monocyte Plasmacytoid dendritic cell Hepatic stellate cell Macrophage Endothelial cell of pericentral hepatic sinusoid Cholangiocyte Mesothelial cell B cell Peritoneal macrophage Basophil Conventional dendritic cell Fibroblast

Liver

10-month-old stage

Metabolic dysfunction-associated steatotic liver disease

Male

Visium spatial gene expression v1

Mus musculus

Endothelial cell of hepatic sinusoid Neutrophil Hepatocyte Endothelial cell of periportal hepatic sinusoid Erythrocyte Kupffer cell Intermediate monocyte Plasmacytoid dendritic cell Hepatic stellate cell Endothelial cell of pericentral hepatic sinusoid Cholangiocyte Hematopoietic stem cell B cell Peritoneal macrophage Vascular associated smooth muscle cell Fibroblast

Liver

Young adult stage

Normal

Visium spatial gene expression v1

Homo sapiens

Podocyte Endothelial cell of lymphatic vessel Endothelial cell Mast cell Cd8-positive, alpha-beta t cell Iga plasma cell Epithelial cell of proximal tubule Igg plasma cell Epithelial cell of proximal tubule segment 1 Macrophage Cd4-positive, alpha-beta t cell Pericyte Naive thymus-derived cd4-positive, alpha-beta t cell Collagen secreting cell Kidney loop of henle ascending limb epithelial cell Conventional dendritic cell Fibroblast

Kidney

Seventh decade stage

Nonpapillary renal cell carcinoma

Female

Visium spatial gene expression v1

Homo sapiens

Endothelial cell Iga plasma cell Epithelial cell of proximal tubule Igg plasma cell Epithelial cell of proximal tubule segment 1 Macrophage Kidney loop of henle thick ascending limb epithelial cell Mhc-ii-positive classical monocyte Naive thymus-derived cd4-positive, alpha-beta t cell Collagen secreting cell Conventional dendritic cell Fibroblast

Kidney

Seventh decade stage

Nonpapillary renal cell carcinoma

Male

Visium spatial gene expression v1