Homo sapiens

Regulatory t cell B cell Enterocyte Pericyte Malignant cell Smooth muscle cell Myofibroblast cell Macrophage Cd8-positive, alpha-beta t cell Endothelial tip cell Inflammatory macrophage Endothelial cell Mast cell Endothelial stalk cell

Caecum

Ninth decade stage

Colorectal cancer

Male

Visium spatial gene expression v1

Homo sapiens

T cell Macrophage Endothelial cell Epithelial cell Fibroblast

Thymus

6-month-old stage

Normal

Female

Visium spatial gene expression v1

Homo sapiens

T cell B cell Malignant cell Epithelial cell Myeloid cell

Breast

Adult stage

Triple-negative breast carcinoma

Female

Visium spatial gene expression v1

Mus musculus

Goblet cell Enterocyte Memory b cell Neutrophil Transit amplifying cell Myofibroblast cell Stem cell Group 3 innate lymphoid cell Enteric neuron Germinal center b cell Epithelial cell Fibroblast

Colon

Prime adult stage

Normal

Visium spatial gene expression v1

Homo sapiens

Schwann cell T cell Pericyte Endothelial cell Epithelial cell Fibroblast

Thymus

16th week post-fertilization stage

Normal

Visium spatial gene expression v1

Homo sapiens

Goblet cell Regulatory t cell B cell Enterocyte Pericyte Iga plasma cell Conventional dendritic cell Endothelial cell of lymphatic vessel Malignant cell Smooth muscle cell Cd4-positive, alpha-beta t cell Myofibroblast cell Macrophage Cd8-positive, alpha-beta t cell Igg plasma cell Endothelial tip cell Stromal cell Transit amplifying cell of colon Enteroglial cell Mast cell Endothelial stalk cell

Rectum

Sixth decade stage

Colorectal cancer

Female

Visium spatial gene expression v1

Homo sapiens

Schwann cell Basal cell of epidermis Pericyte Endothelial cell of lymphatic vessel Macrophage Endothelial cell of vascular tree Suprabasal keratinocyte Fibroblast

Skin of cheek

76-year-old stage

Normal

Male

Visium spatial gene expression v1

Homo sapiens

Natural killer cell Myoepithelial cell Dendritic cell T cell Naive b cell Memory b cell Endothelial cell of lymphatic vessel Monocyte Malignant cell Mature nk t cell Perivascular cell Cd4-positive, alpha-beta t cell Macrophage Cd8-positive, alpha-beta t cell Luminal epithelial cell of mammary gland Endothelial cell Plasmablast Fibroblast Myeloid cell

Breast

88-year-old stage

Invasive ductal breast carcinoma

Female

Visium spatial gene expression v1

Homo sapiens

Dendritic cell Iga plasma cell Duct epithelial cell Cd4-positive, alpha-beta t cell Endothelial cell Ionocyte Fibroblast Acinar cell of salivary gland

Labial gland

41-year-old stage

Immune system disorder Normal

Female

Visium spatial gene expression v1

Homo sapiens

Plasmacytoid dendritic cell Erythroid lineage cell T cell Common myeloid progenitor Conventional dendritic cell Myofibroblast cell Macrophage Megakaryocyte Vascular associated smooth muscle cell Cycling dendritic cell Mature b cell Epithelial cell Fibroblast Plasma cell Megakaryocyte progenitor cell Mesothelial cell

Spleen

18th week post-fertilization stage

Normal

Visium spatial gene expression v1

Mus musculus

Plasmacytoid dendritic cell Hepatocyte Hepatic stellate cell Innate lymphoid cell Endothelial cell of hepatic sinusoid Peritoneal macrophage Cholangiocyte B cell Conventional dendritic cell Neutrophil Kupffer cell Endothelial cell of periportal hepatic sinusoid Macrophage Intermediate monocyte Erythrocyte Endothelial cell of pericentral hepatic sinusoid Basophil Fibroblast Cytotoxic t cell Mesothelial cell

Liver

10-month-old stage

Metabolic dysfunction-associated steatotic liver disease

Male

Visium spatial gene expression v1

Homo sapiens

T cell B cell Malignant cell Perivascular cell Endothelial cell Epithelial cell Fibroblast Myeloid cell

Breast

Adult stage

Triple-negative breast carcinoma

Female

Visium spatial gene expression v1