Mus musculus

T cell Granulosa cell Blood vessel endothelial cell Stromal cell Endothelial cell of lymphatic vessel Cumulus granulosa cell Mast cell Smooth muscle cell Steroidogenic stromal cell of ovary Endothelial cell of vascular tree Ovarian surface epithelial cell Adipocyte Macrophage Oviduct secretory cell Plasma cell Oocyte Late luteal cell Atretic granulosa cell Early luteal cell Theca cell Dendritic cell Ovarian fibroblast Mural granulosa cell

Ovary

9-month-old stage

Normal

Female

Slide-seqv2

Mus musculus

T cell Granulosa cell Blood vessel endothelial cell Stromal cell Endothelial cell of lymphatic vessel Cumulus granulosa cell Smooth muscle cell Steroidogenic stromal cell of ovary Endothelial cell of vascular tree Ovarian surface epithelial cell Adipocyte Macrophage Oviduct secretory cell Oocyte Late luteal cell Atretic granulosa cell Early luteal cell Theca cell Dendritic cell Ovarian fibroblast Mural granulosa cell

Ovary

3-month-old stage

Normal

Female

Slide-seqv2

Mus musculus

Glutamatergic neuron Endothelial cell Gabaergic neuron

Primary motor cortex

22-week-old stage 5-week-old stage 9-week-old stage 15-week-old stage 13-week-old stage 24-week-old stage 26-week-old stage 12-week-old stage 20-week-old stage 14-week-old stage Prime adult stage 29-week-old stage 19-week-old stage 18-week-old stage 25-week-old stage 11-week-old stage 7-week-old stage 6-week-old stage 10-week-old stage 23-week-old stage 17-week-old stage 16-week-old stage 8-week-old stage

Normal

Female Male

Patch-seq 10x 3' v2

Cell

Drosophila melanogaster

Fat cell Somatic precursor cell Midgut large flat cell Enteroendocrine cell Adult midgut enterocyte Copper cell Epithelial cell Muscle cell Enterocyte of anterior adult midgut epithelium Intestinal stem cell Enterocyte of posterior adult midgut epithelium Enteroblast Adult differentiating enterocyte

Gut

Day 5 of adulthood

Normal

Female Male

10x 3' v3

Homo sapiens

Transit amplifying cell of small intestine Intestinal crypt stem cell of colon Best4+ enterocyte Epithelial cell of small intestine Enterocyte of epithelium of small intestine Intestinal tuft cell Small intestine goblet cell Transit amplifying cell of colon Tuft cell of colon Paneth cell of epithelium of small intestine Enteroendocrine cell of small intestine Microfold cell of epithelium of small intestine Colon goblet cell Progenitor cell Intestinal crypt stem cell of small intestine Enterocyte of epithelium of large intestine Enteroendocrine cell of colon

Duodenal mucosa Jejunal mucosa Mucosa of ascending colon Mucosa of transverse colon Ileal mucosa Mucosa of descending colon

53-year-old stage 29-year-old stage 45-year-old stage

Normal

Male

10x 3' v3

Cell

Homo sapiens

T cell Natural killer cell Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Amygdala excitatory neuron Committed oligodendrocyte precursor Hippocampal ca1-3 neuron Lamp5 lhx6 neuron Eccentric medium spiny neuron Pvalb chandelier gabaergic interneuron Medial ganglionic eminence derived interneuron Ependymal cell Microglial cell Pericyte Cerebral cortex neuron Near-projecting glutamatergic cortical neuron Neuron Monocyte Intratelencephalic-projecting glutamatergic cortical neuron Caudal ganglionic eminence derived interneuron Vascular associated smooth muscle cell Sst chodl gabaergic interneuron Astrocyte Fibroblast Medium spiny neuron

Supraoptic nucleus

50-year-old stage

Normal

Male

10x 3' v3

Nucleus

Drosophila melanogaster

Neuron Adult abdominal pericardial cell Indirect flight muscle cell Fat cell Cardial cell Tracheolar cell Hemocyte Epithelial cell Muscle cell Adult tracheocyte Embryonic/larval crystal cell Oenocyte Adult oenocyte Adult heart ventral longitudinal muscle cell

Heart

Day 5 of adulthood

Normal

Female Male

10x 3' v3

Mus musculus

Podocyte Endothelial cell Kidney interstitial fibroblast Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney granular cell Kidney collecting duct principal cell Kidney loop of henle thick ascending limb epithelial cell Macula densa epithelial cell Mesangial cell Kidney proximal convoluted tubule epithelial cell

Kidney

6-month-old stage

Autosomal dominant polycystic kidney disease

Male

Slide-seqv2

Mus musculus

Podocyte Endothelial cell Kidney interstitial fibroblast Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney granular cell Kidney collecting duct principal cell Kidney loop of henle thick ascending limb epithelial cell Macula densa epithelial cell Mesangial cell Kidney proximal convoluted tubule epithelial cell

Kidney

6-month-old stage

Autosomal dominant polycystic kidney disease

Male

Slide-seqv2

Homo sapiens

Podocyte Parietal epithelial cell Endothelial cell Kidney loop of henle thin descending limb epithelial cell Kidney interstitial fibroblast Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Leukocyte Kidney distal convoluted tubule epithelial cell Kidney collecting duct principal cell Kidney connecting tubule epithelial cell Kidney loop of henle thick ascending limb epithelial cell Kidney loop of henle epithelial cell Mesangial cell Pericyte Kidney proximal convoluted tubule epithelial cell

Renal medulla

64-year-old stage

Normal

Female

Slide-seqv2

Homo sapiens

Iga plasma cell Igg plasma cell Unswitched memory b cell Naive b cell Class switched memory b cell

Breast

Adult stage Prime adult stage

Normal

Female

10x 3' v3 10x 3' v2

Cell

Homo sapiens

T cell Hepatocyte Endothelial cell Mature nk t cell Macrophage Plasma cell Malignant cell B cell Monocyte Fibroblast

Liver

40-year-old stage

Breast cancer

Female

10x 3' v3

Cell