Homo sapiens

Monocyte Macrophage Myeloid cell

Breast

43-year-old stage 54-year-old stage 49-year-old stage 42-year-old stage 55-year-old stage 88-year-old stage 82-year-old stage 57-year-old stage 60-year-old stage 35-year-old stage 63-year-old stage 61-year-old stage 67-year-old stage 47-year-old stage 52-year-old stage 58-year-old stage 85-year-old stage 50-year-old stage 73-year-old stage 41-year-old stage

Breast carcinoma Invasive ductal breast carcinoma Invasive lobular breast carcinoma

Female

10x 3' v2 10x 5' v1 10x 3' v3

Cell

Mus musculus

T cell Regular atrial cardiac myocyte B cell Regular ventricular cardiac myocyte Endothelial cell of coronary artery Monocyte Cardiac valve cell Smooth muscle cell Macrophage Fibroblast of cardiac tissue Endocardial cell

Heart

20-month-old stage and over 18-month-old stage 3-month-old stage

Normal

Female Male

Smart-seq2

Cell

Homo sapiens

Pituitary gland cell Epithelial cell of thyroid gland Ectodermal cell Peridermal cell Neuroplacodal cell

Pharyngeal arch system

Carnegie stage 12 Carnegie stage 20 Carnegie stage 16 Carnegie stage 14 Carnegie stage 13 Carnegie stage 17

Normal

Female Male

10x multiome

Nucleus

Homo sapiens

Endothelial cell of artery Regular ventricular cardiac myocyte Glial cell Endothelial cell of lymphatic vessel Neutrophil Monocyte Cd8-positive, alpha-beta cytotoxic t cell Smooth muscle cell Macrophage Fibroblast of cardiac tissue Adipocyte Smooth muscle cell of the pulmonary artery Cd14-positive monocyte Capillary endothelial cell Vein endothelial cell Plasma cell Mast cell Mesothelial cell

Heart left ventricle

Seventh decade stage

Normal

Female Male

Visium spatial gene expression v1

Homo sapiens

Pulmonary alveolar type 2 cell Lung multiciliated epithelial cell Basal cell Respiratory tract epithelial cell Pulmonary neuroendocrine cell

Lung

Normal

10x 5' v1

Cell

Mus musculus

Tracheal epithelial cell

Tracheal epithelial cell

Mature stage

Normal

10x 3' v3

Cell

Mus musculus

Pituitary gland cell Mesenchymal cell Ectodermal cell Peridermal cell Neuroplacodal cell Myeloid cell

Pharyngeal arch system

Theiler stage 21 Theiler stage 20 Theiler stage 23 Theiler stage 19 Theiler stage 22 Theiler stage 17

Normal

10x multiome 10x 3' v3

Nucleus

Homo sapiens

Keratinocyte

Skin epidermis Skin of body

56-year-old stage 39-year-old stage 65-year-old stage 40-year-old stage

Normal

Female Male

10x 3' v2 10x 3' v3

Cell

Homo sapiens

Caudal ganglionic eminence derived interneuron

Dorsolateral prefrontal cortex

42-year-old stage 68-year-old stage 88-year-old stage 86-year-old stage 82-year-old stage 83-year-old stage 75-year-old stage 80-year-old stage 77-year-old stage 89-year-old stage 78-year-old stage 72-year-old stage 80 year-old and over stage 81-year-old stage 87-year-old stage 84-year-old stage 85-year-old stage 50-year-old stage 29-year-old stage 69-year-old stage 70-year-old stage

Dementia Normal

Female Male

10x multiome 10x 3' v3

Nucleus

Homo sapiens

Hepatocyte Endothelial cell of hepatic sinusoid Endothelial cell of artery Endothelial cell of periportal hepatic sinusoid Endothelial cell of pericentral hepatic sinusoid Vein endothelial cell

Caudate lobe of liver

Young adult stage Prime adult stage Late adult stage

Normal

Female Male

10x 3' v2 10x 5' v1

Cell

Homo sapiens

Monocyte Malignant cell Mature nk t cell Macrophage Blood vessel smooth muscle cell Endothelial cell Blood vessel endothelial cell Fibroblast

Liver

46-year-old stage

Breast cancer

Female

Slide-seqv2

Homo sapiens

Natural killer cell Pulmonary alveolar type 2 cell Naive thymus-derived cd4-positive, alpha-beta t cell Dendritic cell Alveolar macrophage Effector memory cd8-positive, alpha-beta t cell Club cell B cell Endothelial cell of artery Lung multiciliated epithelial cell Non-classical monocyte Pericyte Endothelial cell of lymphatic vessel Neutrophil Pulmonary ionocyte Lymphocyte Classical monocyte Mature nk t cell Myofibroblast cell Intermediate monocyte Basal cell Naive thymus-derived cd8-positive, alpha-beta t cell Plasmacytoid dendritic cell, human Vascular associated smooth muscle cell Lung goblet cell Bronchial smooth muscle cell Myeloid leukocyte Endothelial cell Dendritic cell, human Capillary endothelial cell Pulmonary alveolar type 1 cell Vein endothelial cell Epithelial cell Effector memory cd4-positive, alpha-beta t cell Fibroblast Pulmonary neuroendocrine cell Plasma cell Pulmonary interstitial fibroblast Respiratory basal cell Cd1c-positive myeloid dendritic cell

Lung Blood

46-year-old stage 75-year-old stage 51-year-old stage

Normal

Female Male

Smart-seq2

Cell