Homo sapiens

Oligodendrocyte precursor cell

Substantia nigra pars compacta

49-year-old stage 91-year-old stage 82-year-old stage 83-year-old stage 75-year-old stage 92-year-old stage 74-year-old stage 76-year-old stage 89-year-old stage 78-year-old stage 79-year-old stage 90-year-old stage 70-year-old stage

Parkinson disease Lewy body dementia Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Erythroid lineage cell Hepatocyte Centrilobular region hepatocyte Erythroblast Midzonal region hepatocyte Periportal region hepatocyte

Caudate lobe of liver

Young adult stage Prime adult stage Late adult stage

Normal

Female Male

10x 3' v2 10x 5' v1

Cell

Homo sapiens

Oligodendrocyte Natural killer cell Astrocyte Purkinje cell Bergmann glial cell T cell Medial ganglionic eminence derived interneuron Microglial cell Oligodendrocyte precursor cell Neuron Ependymal cell Pericyte Committed oligodendrocyte precursor Monocyte Cerebellar inhibitory gabaergic interneuron Cerebellar granule cell Intratelencephalic-projecting glutamatergic cortical neuron Vascular associated smooth muscle cell Endothelial cell Caudal ganglionic eminence derived interneuron Choroid plexus epithelial cell Central nervous system macrophage Midbrain-derived inhibitory neuron Fibroblast Lamp5 lhx6 neuron Unipolar brush cell

Nucleus of medulla oblongata

42-year-old stage 50-year-old stage 29-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Glycinergic amacrine cell Gabaergic amacrine cell

Fovea centralis Peripheral region of retina

64-year-old stage 60-year-old stage 74-year-old stage 78-year-old stage 65-year-old stage 53-year-old stage 69-year-old stage

Normal

Female Male

10x 3' v2 10x 3' v3

Cell

Homo sapiens

Intermediate cell of urothelium Umbrella cell of urothelium Basal cell of urothelium

Ureter

68-year-old stage 82-year-old stage 75-year-old stage 74-year-old stage 81-year-old stage 79-year-old stage 65-year-old stage 85-year-old stage 69-year-old stage

Normal

Female Male

10x 3' v3

Cell

Mus musculus

Microglial cell Macrophage

Brain

20-month-old stage and over 18-month-old stage 3-month-old stage

Normal

Female Male

Smart-seq2

Cell

Homo sapiens

Oligodendrocyte Natural killer cell Astrocyte T cell Medial ganglionic eminence derived interneuron Microglial cell Oligodendrocyte precursor cell B cell Neuron Ependymal cell Pericyte Committed oligodendrocyte precursor Monocyte Intratelencephalic-projecting glutamatergic cortical neuron Vascular associated smooth muscle cell Endothelial cell Caudal ganglionic eminence derived interneuron Thalamic excitatory neuron Choroid plexus epithelial cell Central nervous system macrophage Midbrain-derived inhibitory neuron Fibroblast Lamp5 lhx6 neuron

Nucleus of dorsal thalamus

50-year-old stage

Normal

Male

10x 3' v3

Nucleus

Mus musculus

Pituitary gland cell

Pituitary hormone deficiency, combined, 2 Normal

10x 3' v3

Microcebus murinus

Natural killer cell Dendritic cell Erythroid lineage cell T cell B cell Endothelial cell of artery Pericyte Reticular cell Conventional dendritic cell Endothelial cell of lymphatic vessel Neutrophil Pancreatic acinar cell Non-myelinating schwann cell Monocyte Mature nk t cell Smooth muscle cell Cd4-positive, alpha-beta t cell Myofibroblast cell Macrophage Cd8-positive, alpha-beta t cell Vascular associated smooth muscle cell Adipocyte Tendon cell Endothelial cell Capillary endothelial cell Urothelial cell Basophil Vein endothelial cell Epithelial cell Fibroblast Granulosa cell Plasma cell Mesothelial cell

Gonadal fat pad Subcutaneous adipose tissue Adipose tissue Brown adipose tissue Mesenteric fat pad

Post-juvenile adult stage

Normal

Female Male

10x 3' v2

Cell

Homo sapiens

Oligodendrocyte Natural killer cell Astrocyte T cell Medial ganglionic eminence derived interneuron Pvalb chandelier gabaergic interneuron Microglial cell Oligodendrocyte precursor cell B cell Neuron Ependymal cell Pericyte Committed oligodendrocyte precursor Monocyte Endothelial cell Amygdala excitatory neuron Caudal ganglionic eminence derived interneuron Central nervous system macrophage Midbrain-derived inhibitory neuron Fibroblast Lamp5 lhx6 neuron Mammillary body neuron

Median tuberal portion

50-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Hepatocyte T cell B cell Monocyte Malignant cell Mature nk t cell Macrophage Endothelial cell Fibroblast

Liver

55-year-old stage

Breast cancer

Female

10x 3' v2

Cell

Homo sapiens

Plasmacytoid dendritic cell Natural killer cell Naive thymus-derived cd4-positive, alpha-beta t cell Erythroid lineage cell Precursor b cell Late promyelocyte Effector memory cd8-positive, alpha-beta t cell Erythroid progenitor cell Cd4-positive, alpha-beta memory t cell Non-classical monocyte Naive b cell Gamma-delta t cell Conventional dendritic cell Central memory cd8-positive, alpha-beta t cell Classical monocyte Pro-b cell Small pre-b-ii cell Naive thymus-derived cd8-positive, alpha-beta t cell Lymphoid lineage restricted progenitor cell Fraction a pre-pro b cell Immature b cell Class switched memory b cell Pre-natural killer cell Common dendritic progenitor Unswitched memory b cell Basophil mast progenitor cell Cd16-negative, cd56-bright natural killer cell, human Early promyelocyte Hematopoietic multipotent progenitor cell Megakaryocyte-erythroid progenitor cell Plasma cell Cd8-positive, alpha-beta memory t cell Megakaryocyte progenitor cell Myelocyte Cd16-positive, cd56-dim natural killer cell, human

Bone marrow

26-year-old stage

Normal

Male

Bd rhapsody whole transcriptome analysis

Cell