Homo sapiens

L2/3-6 intratelencephalic projecting glutamatergic neuron

Dorsolateral prefrontal cortex

42-year-old stage 68-year-old stage 88-year-old stage 86-year-old stage 82-year-old stage 83-year-old stage 75-year-old stage 80-year-old stage 77-year-old stage 89-year-old stage 78-year-old stage 72-year-old stage 80 year-old and over stage 81-year-old stage 87-year-old stage 84-year-old stage 85-year-old stage 50-year-old stage 29-year-old stage 69-year-old stage 70-year-old stage

Dementia Normal

Female Male

10x multiome 10x 3' v3

Nucleus

Mus musculus

Tracheal epithelial cell

Tracheal epithelial cell

Mature stage

Normal

10x 3' v3

Cell

Homo sapiens

Secondary lens fiber Lens fiber cell Anterior lens cell Lens epithelial cell

Lens of camera-type eye

33-year-old stage Adult stage

Normal

Male

10x 3' v3

Nucleus

Mus musculus

Oligodendrocyte Astrocyte Microglial cell Oligodendrocyte precursor cell Brain microvascular endothelial cell Obsolete inhibitory neuron

Normal

10x 3' v2

Homo sapiens

Colon goblet cell Tuft cell of colon Secretory cell Malignant cell Colonocyte Enteroendocrine cell of colon Intestinal crypt stem cell of colon Best4+ colonocyte Early colonocyte

Caecum Liver Sigmoid colon Hepatic flexure of colon

49-year-old stage 64-year-old stage 68-year-old stage 74-year-old stage 39-year-old stage 65-year-old stage 50-year-old stage 45-year-old stage 37-year-old stage

Colorectal cancer Normal

Female Male

10x 3' v3

Cell

Mus musculus

Kidney loop of henle thick ascending limb epithelial cell Kidney interstitial fibroblast Leukocyte Kidney proximal convoluted tubule epithelial cell Podocyte Macrophage Blood vessel smooth muscle cell Endothelial cell Mesangial cell Kidney distal convoluted tubule epithelial cell

Kidney

13-week-old stage

Normal

Male

Slide-seqv2

Oryctolagus cuniculus

Large intestine goblet cell Enterocyte of epithelium of large intestine Intestinal crypt stem cell of large intestine Transit amplifying cell Enteroendocrine cell Best4+ enterocyte

Normal

10x 3' v3

Drosophila melanogaster

Neuron Muscle cell Male accessory gland main cell Hemocyte Male accessory gland secondary cell Spermatocyte Spermatid

Male reproductive gland

Day 2 of adulthood

Normal

Male

10x 3' v3

Mus musculus

Astrocyte

Normal

Mixed sex

10x 3' v2

Homo sapiens

Kidney loop of henle thick ascending limb epithelial cell Kidney interstitial fibroblast Leukocyte Kidney proximal convoluted tubule epithelial cell Podocyte Parietal epithelial cell Pericyte Kidney collecting duct principal cell Blood vessel smooth muscle cell Kidney loop of henle thin descending limb epithelial cell Endothelial cell Kidney loop of henle epithelial cell Kidney collecting duct intercalated cell Mesangial cell Kidney connecting tubule epithelial cell Kidney distal convoluted tubule epithelial cell

Renal medulla

75-year-old stage

Normal

Male

Slide-seqv2

Homo sapiens

Kidney loop of henle thick ascending limb epithelial cell Kidney interstitial fibroblast Leukocyte Kidney collecting duct principal cell Macrophage Blood vessel smooth muscle cell Endothelial cell Kidney collecting duct intercalated cell Kidney distal convoluted tubule epithelial cell

Renal medulla

64-year-old stage

Normal

Female

Slide-seqv2

Drosophila melanogaster

Adult renal stem cell Visceral muscle cell

Malpighian tubule

Day 5 of adulthood

Normal

Female Male

10x 3' v3