Homo sapiens

Secretory cell

Ampulla of fallopian tube Isthmus of fallopian tube Fallopian tube Fimbria of fallopian tube

31-year-old stage 30-year-old stage 46-year-old stage 52-year-old stage

Normal

Female

10x 3' v3

Cell

Homo sapiens

Oligodendrocyte Natural killer cell Astrocyte T cell Medial ganglionic eminence derived interneuron Pvalb chandelier gabaergic interneuron Microglial cell Oligodendrocyte precursor cell Neuron Ependymal cell Pericyte Committed oligodendrocyte precursor Cerebellar granule cell Intratelencephalic-projecting glutamatergic cortical neuron Sst chodl gabaergic interneuron Hippocampal ca1-3 neuron Endothelial cell Amygdala excitatory neuron Caudal ganglionic eminence derived interneuron Dentate gyrus granule cell Thalamic excitatory neuron Central nervous system macrophage Midbrain-derived inhibitory neuron Fibroblast Lamp5 lhx6 neuron Mammillary body neuron Unipolar brush cell

Medial geniculate body

42-year-old stage 29-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Adipocyte of omentum tissue

Visceral fat

34-year-old stage 24-year-old stage 28-year-old stage 33-year-old stage 48-year-old stage Adult stage 53-year-old stage 29-year-old stage 41-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Drosophila melanogaster

Muscle cell Epithelial cell Hemocyte Mechanosensory neuron

Leg

Day 2 of adulthood Day 5 of adulthood

Normal

Female Male

10x 3' v3

Homo sapiens

Kidney loop of henle thick ascending limb epithelial cell Kidney interstitial fibroblast Leukocyte Kidney proximal convoluted tubule epithelial cell Podocyte Parietal epithelial cell Pericyte Kidney collecting duct principal cell Blood vessel smooth muscle cell Kidney loop of henle thin descending limb epithelial cell Endothelial cell Kidney loop of henle epithelial cell Urothelial cell Kidney collecting duct intercalated cell Mesangial cell Kidney connecting tubule epithelial cell Kidney distal convoluted tubule epithelial cell

Renal medulla

75-year-old stage

Normal

Male

Slide-seqv2

Homo sapiens

Endothelial cell of lymphatic vessel Endothelial cell of coronary artery Endothelial cell Vein endothelial cell

Prostate gland

62-year-old stage 54-year-old stage 59-year-old stage 64-year-old stage 46-year-old stage 68-year-old stage 60-year-old stage 75-year-old stage 63-year-old stage 61-year-old stage 72-year-old stage 45-year-old stage 69-year-old stage 70-year-old stage 71-year-old stage

Prostatic acinar adenocarcinoma

Male

10x 3' v3

Cell

Homo sapiens

Natural killer cell Pancreatic d cell T cell B cell Non-classical monocyte Neutrophil Pancreatic acinar cell Type b pancreatic cell Classical monocyte Monocyte Mature nk t cell Cd4-positive, alpha-beta t cell Macrophage Intermediate monocyte Cd8-positive, alpha-beta t cell Pancreatic stellate cell Endothelial cell Pancreatic pp cell Pancreatic ductal cell Fibroblast Plasma cell Mast cell Pancreatic a cell

Endocrine pancreas Exocrine pancreas

59-year-old stage 56-year-old stage 37-year-old stage

Normal

Female Male

10x 3' v3

Cell

Homo sapiens

Oligodendrocyte Natural killer cell Astrocyte T cell Medial ganglionic eminence derived interneuron Pvalb chandelier gabaergic interneuron Microglial cell Oligodendrocyte precursor cell B cell Neuron Ependymal cell Pericyte Committed oligodendrocyte precursor Monocyte Cerebellar inhibitory gabaergic interneuron Cerebral cortex neuron Cerebellar granule cell Intratelencephalic-projecting glutamatergic cortical neuron Vascular associated smooth muscle cell Endothelial cell Amygdala excitatory neuron Caudal ganglionic eminence derived interneuron Medium spiny neuron Thalamic excitatory neuron Central nervous system macrophage Midbrain-derived inhibitory neuron Fibroblast Lamp5 lhx6 neuron

Gray matter of midbrain

50-year-old stage 29-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Plasmacytoid dendritic cell Conventional dendritic cell Neutrophil Classical monocyte

Lung Adrenal gland Brain Pleural effusion Liver Lymph node Axilla Bone spine

62-year-old stage 64-year-old stage 68-year-old stage 55-year-old stage 82-year-old stage 57-year-old stage 75-year-old stage 80-year-old stage 77-year-old stage 74-year-old stage 76-year-old stage 78-year-old stage 72-year-old stage 67-year-old stage 47-year-old stage 81-year-old stage 79-year-old stage 44-year-old stage 84-year-old stage 65-year-old stage 85-year-old stage 69-year-old stage 73-year-old stage 70-year-old stage 71-year-old stage

Small cell lung carcinoma Lung adenocarcinoma Normal

Female Male

10x 3' v2 10x 3' transcription profiling 10x 3' v3

Cell

Mus musculus

Trigeminal neuron

Trigeminal ganglion

8-week-old stage

Peripheral neuropathy Normal

Female Male

Drop-seq Indrop Smart-seq3 10x 3' v3 Bd rhapsody whole transcriptome analysis

Cell Nucleus

Homo sapiens

Kidney loop of henle thick ascending limb epithelial cell Kidney interstitial fibroblast Leukocyte Kidney proximal convoluted tubule epithelial cell Podocyte Kidney collecting duct principal cell Macrophage Blood vessel smooth muscle cell Endothelial cell Kidney collecting duct intercalated cell Mesangial cell Kidney granular cell Kidney distal convoluted tubule epithelial cell

Cortex of kidney

65-year-old stage

Normal

Male

Slide-seqv2

Homo sapiens

Adipocyte of omentum tissue

Visceral fat

34-year-old stage 24-year-old stage 28-year-old stage 33-year-old stage 48-year-old stage Adult stage 53-year-old stage 29-year-old stage 41-year-old stage

Normal

Female Male

10x 3' v3

Nucleus