Mus musculus

Megakaryocyte

Embryo

Theiler stage 22 Theiler stage 27 Theiler stage 24 Theiler stage 18 Theiler stage 25 Theiler stage 14 Theiler stage 16 Theiler stage 17 Theiler stage 15 Theiler stage 19 Theiler stage 26 Theiler stage 13 Theiler stage 20 Theiler stage 12 Theiler stage 21 Theiler stage 23

Normal

Female Male

Sci-rna-seq3

Nucleus

Drosophila melanogaster

Mechanosensory neuron of leg chordotonal organ Tracheolar cell Glial cell Gustatory receptor neuron Hemocyte Epithelial cell Muscle cell Adult tracheocyte Mechanosensory neuron Sensory neuron

Leg

Day 5 of adulthood Day 2 of adulthood

Normal

Female Male

10x 3' v3

Homo sapiens

Cd1c-positive myeloid dendritic cell Cd141-positive myeloid dendritic cell Plasmacytoid dendritic cell Dendritic cell

Synovial fluid Blood

Pediatric stage 2-year-old stage 15-year-old stage 9-year-old stage 14-year-old stage 3-year-old stage 7-year-old stage 10-year-old stage

Juvenile idiopathic arthritis

Female Male

10x 5' v2 10x 3' v3

Cell

Homo sapiens

Cd8-positive, alpha-beta t cell Cd4-positive helper t cell Epithelial cell Regulatory t cell Myeloid cell Plasma cell Malignant cell B cell Fibroblast

Lung

61-year-old stage

Renal cell carcinoma

Male

Slide-seqv2

Homo sapiens

Midbrain-derived inhibitory neuron T cell Central nervous system macrophage Natural killer cell Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Amygdala excitatory neuron Committed oligodendrocyte precursor Lamp5 lhx6 neuron Eccentric medium spiny neuron Pvalb chandelier gabaergic interneuron Medial ganglionic eminence derived interneuron Ependymal cell Microglial cell Pericyte Cerebral cortex neuron Near-projecting glutamatergic cortical neuron Neuron Intratelencephalic-projecting glutamatergic cortical neuron Caudal ganglionic eminence derived interneuron Sst chodl gabaergic interneuron Astrocyte Fibroblast Medium spiny neuron

Preoptic area

50-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Natural killer cell Gamma-delta t cell Cd4-positive helper t cell Natural t-regulatory cell Activated cd8-positive, alpha-beta t cell Memory t cell

Duodenum Ileal epithelium Epithelium of rectum Submucosal esophageal gland Body of stomach Cardia of stomach Ascending colon epithelium Esophagogastric junction Lower esophagus

66-year-old stage 69-year-old stage 34-year-old stage 42-year-old stage 43-year-old stage 53-year-old stage 68-year-old stage 48-year-old stage 29-year-old stage 56-year-old stage 55-year-old stage 50-year-old stage 51-year-old stage 57-year-old stage 74-year-old stage 80 year-old and over stage 58-year-old stage 67-year-old stage 77-year-old stage 45-year-old stage 62-year-old stage 41-year-old stage 63-year-old stage 83-year-old stage 27-year-old stage

Barrett esophagus Normal Gastric intestinal metaplasia Gastritis

Female Male

10x 3' v3 10x 3' v2

Cell

Mus musculus

Podocyte Endothelial cell Kidney interstitial fibroblast Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney collecting duct principal cell Kidney loop of henle thick ascending limb epithelial cell Mesangial cell Kidney proximal convoluted tubule epithelial cell

Kidney

13-week-old stage

Diabetic kidney disease

Male

Slide-seqv2

Mus musculus

Mesothelial cell

Periovarian fat pad Epididymal fat pad

19-week-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Endothelial cell

Substantia nigra pars compacta

75-year-old stage 91-year-old stage 89-year-old stage 92-year-old stage 82-year-old stage 90-year-old stage 74-year-old stage 49-year-old stage 70-year-old stage 78-year-old stage 76-year-old stage 79-year-old stage 83-year-old stage

Parkinson disease Normal Lewy body dementia

Female Male

10x 3' v3

Nucleus

Microcebus murinus

T cell Neutrophil Podocyte Renal principal cell Stromal cell Natural killer cell Endothelial cell of lymphatic vessel Erythroid progenitor cell Renal beta-intercalated cell Non-myelinating schwann cell Glomerular endothelial cell Reticular cell Kidney loop of henle thin descending limb epithelial cell Mature nk t cell Cd8-positive, alpha-beta t cell Kidney collecting duct intercalated cell Capillary endothelial cell Epithelial cell of proximal tubule Plasmacytoid dendritic cell Renal intercalated cell Vasa recta descending limb cell Renal alpha-intercalated cell Lymphocyte Adipocyte Macrophage Kidney distal convoluted tubule epithelial cell Innate lymphoid cell Urothelial cell Kidney loop of henle thick ascending limb epithelial cell Vasa recta ascending limb cell Kidney loop of henle epithelial cell Macula densa epithelial cell Kidney proximal straight tubule epithelial cell Plasma cell Cd4-positive, alpha-beta t cell Mesothelial cell B cell Pericyte Granulocyte monocyte progenitor cell Monocyte Vascular associated smooth muscle cell Kidney loop of henle thin ascending limb epithelial cell Myofibroblast cell Basophil Conventional dendritic cell Kidney proximal convoluted tubule epithelial cell Fibroblast Dendritic cell

Kidney

Post-juvenile adult stage

Normal

Female Male

Smart-seq2 10x 3' v2

Cell

Microcebus murinus

Homo sapiens

Central memory cd4-positive, alpha-beta t cell Neutrophil Natural killer cell Platelet Classical monocyte Plasmacytoid dendritic cell, human Lymphocyte Naive thymus-derived cd8-positive, alpha-beta t cell Memory b cell Plasmablast Hematopoietic stem cell Naive thymus-derived cd4-positive, alpha-beta t cell Transitional stage b cell Naive b cell Conventional dendritic cell Effector memory cd8-positive, alpha-beta t cell Immature neutrophil Non-classical monocyte

Blood

39-year-old stage 78-year-old stage

Covid-19

Male

10x 3' v2

Cell