Homo sapiens

Microglial cell

Dorsolateral prefrontal cortex

80-year-old stage 85-year-old stage 82-year-old stage 70-year-old stage 77-year-old stage 50-year-old stage 86-year-old stage 80 year-old and over stage 89-year-old stage 75-year-old stage 78-year-old stage 68-year-old stage 42-year-old stage 72-year-old stage 88-year-old stage 84-year-old stage 69-year-old stage 29-year-old stage 87-year-old stage 81-year-old stage 83-year-old stage

Normal Dementia

Female Male

10x 3' v3 10x multiome

Nucleus

Homo sapiens

Luminal cell of prostate epithelium Basal cell of prostate epithelium Epithelial cell of urethra Secretory cell

Transition zone of prostate Peripheral zone of prostate

74-year-old stage 67-year-old stage 71-year-old stage 31-year-old stage 72-year-old stage 73-year-old stage 29-year-old stage 81-year-old stage

Normal Benign prostatic hyperplasia

Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Macrophage Monocyte Granulocyte Conventional dendritic cell Dendritic cell Plasmacytoid dendritic cell Mature conventional dendritic cell

Colorectum

91-year-old stage 82-year-old stage 70-year-old stage 77-year-old stage 50-year-old stage 57-year-old stage 76-year-old stage 62-year-old stage 52-year-old stage 60-year-old stage 48-year-old stage 64-year-old stage 89-year-old stage 45-year-old stage 67-year-old stage 71-year-old stage 78-year-old stage 36-year-old stage 59-year-old stage 47-year-old stage 56-year-old stage 58-year-old stage 61-year-old stage 51-year-old stage 49-year-old stage 42-year-old stage 35-year-old stage 53-year-old stage 72-year-old stage 73-year-old stage 84-year-old stage 90-year-old stage 69-year-old stage 81-year-old stage 55-year-old stage

Normal Colon adenocarcinoma

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Myofibroblast cell Transit amplifying cell of small intestine Best4+ enterocyte Activated cd8-positive, alpha-beta t cell Innate lymphoid cell Small intestine goblet cell Endothelial cell of lymphatic vessel Cd4-positive, alpha-beta t cell Endothelial cell of arteriole Enterocyte of epithelium proper of jejunum Macrophage Naive thymus-derived cd4-positive, alpha-beta t cell Enterocyte of epithelium proper of duodenum Enteroendocrine cell of small intestine Mast cell Enterocyte of epithelium proper of small intestine Endothelial cell of venule Neutrophil Monocyte Myeloid dendritic cell Fibroblast Intestinal tuft cell Enterocyte of epithelium proper of ileum Pericyte Paneth cell of epithelium of small intestine B cell Cd8-positive, alpha-beta t cell Activated cd4-positive, alpha-beta t cell Enteroglial cell Plasma cell Regulatory t cell Intestinal crypt stem cell of small intestine Natural killer cell Gamma-delta t cell

Ileum Small intestine Jejunum Duodenum

60-year-old stage 37-year-old stage 59-year-old stage 56-year-old stage 61-year-old stage

Normal

Female Male

Smart-seq2 10x 3' v3

Cell

Mus musculus

Tracheal epithelial cell

Tracheal epithelial cell

Mature stage

Normal

10x 3' v3

Cell

Homo sapiens

Cardiac endothelial cell Pluripotent stem cell Progenitor cell Hematopoietic stem cell

Embryo Dorsal lateral plate region Embryoid body

Carnegie stage 14 Carnegie stage 11 Carnegie stage 10 Carnegie stage 13 Carnegie stage 15 Carnegie stage 17 Carnegie stage 16

Normal

Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Follicular b cell Innate lymphoid cell Cd4-positive, alpha-beta t cell Iga plasma cell Macrophage T-helper 1 cell Mast cell Monocyte Memory t cell Colon macrophage Conventional dendritic cell T-helper 17 cell B cell Cd8-positive, alpha-beta t cell Dendritic cell Regulatory t cell Memory b cell Plasmacytoid dendritic cell T follicular helper cell Natural killer cell Gamma-delta t cell

Mesenteric lymph node Caecum Transverse colon Sigmoid colon

Fifth decade stage Seventh decade stage Sixth decade stage

Normal

Female Male

10x 5' v2 10x 3' v2

Cell

Homo sapiens

Astrocyte Oligodendrocyte precursor cell Oligodendrocyte Leukocyte Vascular associated smooth muscle cell Fibroblast Ependymal cell Pericyte Endothelial cell Neuron Central nervous system macrophage

Subicular complex

50-year-old stage 42-year-old stage 29-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Activated cd4-positive, alpha-beta t cell, human Naive b cell Classical monocyte Platelet Non-classical monocyte Lymphocyte Naive thymus-derived cd4-positive, alpha-beta t cell Mucosal invariant t cell Transitional stage b cell Cd16-negative, cd56-bright natural killer cell, human Neutrophil Double negative thymocyte Conventional dendritic cell Naive thymus-derived cd8-positive, alpha-beta t cell Central memory cd4-positive, alpha-beta t cell Effector memory cd8-positive, alpha-beta t cell Hematopoietic stem cell Plasmacytoid dendritic cell, human Igg plasmablast Erythrocyte Regulatory t cell Memory b cell Iga plasmablast Natural killer cell Gamma-delta t cell Immature neutrophil

Blood

Fourth decade stage 80 year-old and over stage 48-year-old stage 37-year-old stage 36-year-old stage Fifth decade stage 49-year-old stage Seventh decade stage Third decade stage Sixth decade stage

Normal Covid-19

Female Male

Seq-well

Cell

Drosophila melanogaster

Adult olfactory receptor neuron gr21a/63a Adult olfactory receptor neuron or67d Muscle cell Adult olfactory receptor neuron ir75d Female germline cell Adult olfactory receptor neuron or65 Adult glial cell Tracheolar cell Epithelial cell Neuron Sensory neuron Fat cell Adult olfactory receptor neuron or92a Adult olfactory receptor neuron or47b Hemocyte Adult olfactory receptor neuron or88a Male germline cell Oenocyte Neuron Glial cell Johnston organ neuron Adult olfactory receptor neuron or13a

Antenna

Day 5 of adulthood

Normal

Female Male Mixed sex

10x 3' v3

Homo sapiens

Mural cell Lymphocyte Neutrophil Fibroblast Endothelial cell Mononuclear phagocyte

Left atrium auricular region

Eighth decade stage Ninth decade stage Fifth decade stage Seventh decade stage Sixth decade stage

Normal Atrial fibrillation Mitral valve insufficiency

Female Male

10x 3' v3

Cell

Homo sapiens

Cd4-positive helper t cell Malignant cell B cell Cd8-positive, alpha-beta t cell Plasma cell Regulatory t cell T follicular helper cell Exhausted t cell Myeloid cell

Lymph node

Adult stage

Metastatic melanoma

Slide-seqv2