Macaca mulatta

Microglial cell

Cerebellar vermis Entorhinal cortex Brodmann (1909) area 19 Inferior temporal gyrus Hippocampal formation Cerebrocerebellum Lateral geniculate body Primary somatosensory cortex Perirhinal cortex Corpus callosum Anterior cingulate cortex Primary auditory cortex Dorsolateral prefrontal cortex Pons Primary motor cortex Superior temporal sulcus Midbrain Amygdala Primary visual cortex Superior parietal cortex Medulla oblongata Inferior parietal cortex Ventral lateral nucleus of thalamus Medial dorsal nucleus of thalamus Nucleus accumbens Head of caudate nucleus Prefrontal cortex

Prime adult stage Juvenile stage

Normal

Female Male

Sci-rna-seq3

Nucleus

Homo sapiens

Slow muscle cell Capillary endothelial cell Mesenchymal stem cell Endothelial cell of lymphatic vessel Cd4-positive, alpha-beta t cell Non-classical monocyte Macrophage Skeletal muscle satellite stem cell Mesothelial cell Mast cell Endothelial cell of vascular tree Epithelial cell Neutrophil Monocyte Tendon cell Myeloid dendritic cell Granulocyte Pericyte Endothelial cell Mesenchymal cell Intermediate monocyte B cell Cd8-positive, alpha-beta t cell Plasma cell Erythrocyte Mature nk t cell T cell Smooth muscle cell Basophil Natural killer cell Endothelial cell of artery Fast muscle cell

Muscle of abdomen Muscle of pelvic diaphragm

60-year-old stage 59-year-old stage 56-year-old stage 61-year-old stage 38-year-old stage

Normal

Female Male

Smart-seq2 10x 3' v3

Cell

Homo sapiens

T cell of anorectum Colon epithelial cell Stromal cell of lamina propria of colon Plasma cell Myeloid cell

Colonic mucosa

66-year-old stage 21-year-old stage 46-year-old stage 22-year-old stage 48-year-old stage 45-year-old stage 33-year-old stage 65-year-old stage 23-year-old stage 63-year-old stage 56-year-old stage 68-year-old stage 61-year-old stage 51-year-old stage 49-year-old stage 43-year-old stage

Ulcerative colitis Normal Crohn disease

Female Male

10x 3' v3

Cell

Mus musculus

Skin fibroblast

Skin of body Skin of back

21-day-old stage 12-month-old stage 7-week-old stage 18-month-old stage 22-day-old stage 5-week-old stage 2-month-old stage Prime adult stage 9-week-old stage

Normal Injury

Female Male

10x 3' v3 10x 3' v1 10x 3' v2

Cell

Homo sapiens

Myofibroblast cell Pulmonary alveolar type 1 cell Pulmonary alveolar type 2 cell Club cell Pulmonary neuroendocrine cell Macrophage Alveolar macrophage Mast cell Basal cell Enucleate erythrocyte Epithelial cell Monocyte Vein endothelial cell Vascular associated smooth muscle cell Fibroblast Blood vessel endothelial cell Pericyte Endothelial cell B cell Dendritic cell T cell Smooth muscle cell Natural killer cell Chondrocyte Endothelial cell of artery Ciliated cell Goblet cell

Lung

31st week post-fertilization stage 31-year-old stage 3-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Astrocyte Oligodendrocyte precursor cell Oligodendrocyte Leukocyte Bergmann glial cell Vascular associated smooth muscle cell Fibroblast Ependymal cell Pericyte Endothelial cell Neuron Central nervous system macrophage Choroid plexus epithelial cell

Pulvinar nucleus

50-year-old stage 42-year-old stage 29-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Effector cd8-positive, alpha-beta t cell Cd4-positive helper t cell Cd8-positive, alpha-beta memory t cell Regulatory t cell Gamma-delta t cell Exhausted t cell

Axilla Adrenal gland Liver Lung Brain Pleural effusion Bone spine Lymph node

80-year-old stage 85-year-old stage 82-year-old stage 79-year-old stage 70-year-old stage 77-year-old stage 57-year-old stage 76-year-old stage 62-year-old stage 44-year-old stage 64-year-old stage 74-year-old stage 65-year-old stage 67-year-old stage 75-year-old stage 71-year-old stage 78-year-old stage 47-year-old stage 68-year-old stage 72-year-old stage 73-year-old stage 84-year-old stage 69-year-old stage 81-year-old stage 55-year-old stage

Small cell lung carcinoma Normal Lung adenocarcinoma

Female Male

10x 3' v3 10x 3' v2 10x 3' transcription profiling

Cell

Homo sapiens

Cardiac endothelial cell Smooth muscle myoblast Lymphoid lineage restricted progenitor cell Immature innate lymphoid cell Pericyte Neuronal receptor cell Fibroblast of cardiac tissue Cardiac muscle myoblast

Heart left ventricle

66-year-old stage 57-year-old stage 52-year-old stage 60-year-old stage 44-year-old stage 64-year-old stage 74-year-old stage 40-year-old stage 63-year-old stage 59-year-old stage 47-year-old stage 58-year-old stage 61-year-old stage 51-year-old stage 43-year-old stage 38-year-old stage 55-year-old stage

Normal Myocardial infarction

Female Male

10x scatac-seq

Nucleus

Mus musculus

Glutamatergic neuron Vascular leptomeningeal cell Contractile cell Astrocyte Oligodendrocyte Neural stem cell Neuroblast (sensu vertebrata) Direct pathway medium spiny neuron Neuron associated cell Interneuron Cholinergic neuron Microglial cell Ependymal cell Endothelial cell Striosomal d1 medium spiny neuron Indirect pathway medium spiny neuron Neural cell

Postnatal subventricular zone

5-week-old stage

Normal

Mixed sex

10x genomics v2

Homo sapiens

Inhibitory interneuron Radial glial cell Caudal ganglionic eminence derived interneuron Glutamatergic neuron Astrocyte Oligodendrocyte precursor cell Oligodendrocyte Neural progenitor cell Microglial cell Vascular associated smooth muscle cell Medial ganglionic eminence derived interneuron Pericyte Endothelial cell

Dorsolateral prefrontal cortex Cortical plate

23rd week post-fertilization stage 14-year-old stage 6-year-old stage 19th week post-fertilization stage Infant stage 20-year-old stage 24th week post-fertilization stage 18th week post-fertilization stage 39-year-old stage 4-year-old stage

Normal

Female Male

10x multiome

Nucleus

Homo sapiens

Cerebellar granule cell Capillary endothelial cell Glutamatergic neuron Mural cell Astrocyte Oligodendrocyte precursor cell Oligodendrocyte Gabaergic neuron Leukocyte Committed oligodendrocyte precursor Microglial cell Vascular associated smooth muscle cell Neuron Central nervous system macrophage Endothelial cell of artery

Cervical spinal cord white matter Brodmann (1909) area 4 White matter of cerebellum

44-year-old stage 45-year-old stage 74-year-old stage 40-year-old stage 37-year-old stage 71-year-old stage 63-year-old stage 61-year-old stage 34-year-old stage 42-year-old stage 72-year-old stage 73-year-old stage 39-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

L2/3-6 intratelencephalic projecting glutamatergic neuron

Middle temporal gyrus

80-year-old stage 85-year-old stage 82-year-old stage 70-year-old stage 77-year-old stage 50-year-old stage 86-year-old stage 60-year-old stage 80 year-old and over stage 89-year-old stage 65-year-old stage 75-year-old stage Adult stage 78-year-old stage 68-year-old stage 72-year-old stage 88-year-old stage 84-year-old stage 69-year-old stage 43-year-old stage 29-year-old stage 87-year-old stage 81-year-old stage 83-year-old stage

Normal Dementia

Female Male

10x 3' v3 10x multiome

Nucleus