Homo sapiens

T cell Glutamatergic neuron Oligodendrocyte precursor cell Oligodendrocyte Endothelial cell of artery Capillary endothelial cell Smooth muscle cell Microglial cell Vein endothelial cell Pericyte Perivascular macrophage Astrocyte Fibroblast Gabaergic neuron

Dorsolateral prefrontal cortex

87-year-old stage 88-year-old stage 84-year-old stage 81-year-old stage 90 year-old and over stage 78-year-old stage 79-year-old stage 83-year-old stage

Cognitive disorder Normal Alzheimer disease

Female Male

10x multiome

Nucleus

Mus musculus

Blood vessel endothelial cell Microvascular endothelial cell Tendon cell Schwann cell Smooth muscle cell Lymphocyte Adipocyte Macrophage Type iib muscle cell Type iix muscle cell Fibro/adipogenic progenitor cell Perineurial cell Pericyte Skeletal muscle satellite stem cell Neuromuscular junction nucleus Myotendinous junction nucleus Type iia muscle cell Intermediate muscle cell

Gastrocnemius Skeletal muscle tissue of tibialis anterior

Prime adult stage

Lesion of sciatic nerve Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Intestinal crypt stem cell of colon Gut absorptive cell Goblet cell Tuft cell Intestinal enteroendocrine cell Neoplastic cell Intestinal epithelial cell Transit amplifying cell Abnormal cell

Ascending colon Hepatic flexure of colon Rectum Transverse colon Descending colon Sigmoid colon Hepatic cecum

65-year-old stage 71-year-old stage 53-year-old stage 54-year-old stage 68-year-old stage 50-year-old stage 57-year-old stage 72-year-old stage 58-year-old stage 59-year-old stage 67-year-old stage 64-year-old stage 62-year-old stage 70-year-old stage 60-year-old stage 73-year-old stage

Tubulovillous adenoma Tubular adenoma Colorectal neoplasm Normal Hyperplastic polyp Colon sessile serrated adenoma/polyp

Female Male

Trudrop

Cell

Homo sapiens

Stromal cell Immature t cell Myeloid cell B cell Mature t cell

Myasthenia gravis

10x 5' v2 10x 3' v3

Homo sapiens

Club cell Hepatocyte Pulmonary alveolar epithelial cell Neuroendocrine cell Basal cell Ionocyte Epithelial cell Goblet cell Tuft cell Ciliated epithelial cell

Pleural effusion Lung Axilla Liver Bone spine Brain Adrenal gland Lymph node

69-year-old stage 75-year-old stage 65-year-old stage 71-year-old stage 85-year-old stage 68-year-old stage 44-year-old stage 55-year-old stage 84-year-old stage 82-year-old stage 80-year-old stage 57-year-old stage 72-year-old stage 81-year-old stage 74-year-old stage 67-year-old stage 77-year-old stage 64-year-old stage 62-year-old stage 70-year-old stage 78-year-old stage 47-year-old stage 76-year-old stage 79-year-old stage 73-year-old stage

Lung adenocarcinoma Normal Small cell lung carcinoma

Female Male

10x 3' transcription profiling 10x 3' v3 10x 3' v2

Cell

Homo sapiens

Glutamatergic neuron Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Mature microglial cell Mature astrocyte Gabaergic neuron

Superior frontal gyrus

87-year-old stage 71-year-old stage 82-year-old stage 50-year-old stage 72-year-old stage 80 year-old and over stage 77-year-old stage 60-year-old stage

Normal Alzheimer disease

Male

10x 3' v2

Nucleus

Homo sapiens

Intestine goblet cell Endothelial cell of lymphatic vessel Interstitial cell of cajal Enteric neuron Stem cell Endothelial cell of artery Epithelial cell Neural crest cell Enteroendocrine cell Mesodermal cell Enteric smooth muscle cell Enterocyte Vein endothelial cell Mesothelial cell Pericyte Progenitor cell Colon epithelial cell Myofibroblast cell Erythroblast Fibroblast Hematopoietic cell

Ileum Colon Duodeno-jejunal junction

Carnegie stage 19 Carnegie stage 23 10th week post-fertilization stage Carnegie stage 17 Carnegie stage 22 Carnegie stage 18

Normal

10x 3' v2

Cell

Homo sapiens

Central nervous system macrophage Glutamatergic neuron Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Lymphocyte Ependymal cell Microglial cell Somatomotor neuron Pericyte Astrocyte Fibroblast Gabaergic neuron

Lumbar spinal cord

75-year-old stage 68-year-old stage 80-year-old stage 67-year-old stage 73-year-old stage 83-year-old stage

Amyotrophic lateral sclerosis Normal

Female Male

10x multiome 10x 3' v3

Nucleus

Homo sapiens

Retinal rod cell

Retina

65-year-old stage 77-year-old stage 70-year-old stage 79-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Bipolar neuron Gabaergic amacrine cell Retinal ganglion cell Off-bipolar cell On-bipolar cell Photoreceptor cell Microglial cell Retinal cone cell Retinal rod cell Glial cell Retina horizontal cell Interneuron Amacrine cell Retinal progenitor cell Precursor cell Mueller cell Astrocyte

Normal

Mixed sex

10x 3' v1

Mus musculus

T cell Effector cd8-positive, alpha-beta t cell Neutrophil Seminal vesicle glandular cell Cd1c-positive myeloid dendritic cell Luminal cell of prostate epithelium Natural killer cell Prostate gland microvascular endothelial cell Tissue-resident macrophage Mature nk t cell Cd141-positive myeloid dendritic cell Classical monocyte Intermediate monocyte Plasmacytoid dendritic cell Effector cd4-positive, alpha-beta t cell Lymphocyte Regulatory t cell Fibroblast of connective tissue of prostate Urethra urothelial cell Smooth muscle cell of prostate Plasma cell B cell Fibroblast Basal cell of prostate epithelium Dendritic cell Non-classical monocyte

Prostate gland Urethra

2-month-old stage

Normal

Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Glutamatergic neuron Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Vascular leptomeningeal cell Inhibitory interneuron Microglial cell Astrocyte

Prefrontal cortex White matter of temporal lobe White matter of frontal lobe White matter of occipital lobe White matter of parietal lobe

53-year-old stage 68-year-old stage 82-year-old stage 72-year-old stage 81-year-old stage 70-year-old stage 76-year-old stage 83-year-old stage

Normal Alzheimer disease Leukoencephalopathy, diffuse hereditary, with spheroids 1

Female Male

10x 3' v3

Nucleus