Homo sapiens

Oligodendrocyte Natural killer cell Astrocyte T cell Microglial cell Oligodendrocyte precursor cell B cell Neuron Pericyte Committed oligodendrocyte precursor Monocyte Vascular associated smooth muscle cell Endothelial cell Amygdala excitatory neuron Central nervous system macrophage Fibroblast

Brodmann (1909) area 35

50-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Skeletal muscle satellite stem cell

Intercostal muscle

Fourth decade stage Seventh decade stage Young adult stage Sixth decade stage Eighth decade stage Third decade stage

Normal

Female Male

10x 3' v2 10x 3' v3

Cell

Mus musculus

B cell Colon epithelial cell Lymphocyte Monocyte Macrophage Endothelial cell Cell Granulocyte Fibroblast Mast cell

Normal

Slide-seqv2 10x 3' v2 10x 3' v3

Homo sapiens

Club cell Lung multiciliated epithelial cell Tracheal goblet cell Pulmonary ionocyte Fibroblast of lung Lung secretory cell Basal cell Primary cultured cell

Respiratory airway

55-year-old stage 67-year-old stage 53-year-old stage

Normal

Female Male

10x 3' v2

Cell

Homo sapiens

Plasmacytoid dendritic cell Natural killer cell T cell B cell Conventional dendritic cell Monocyte Platelet

Obsolete type 1 interferonopathy Normal

10x 5' v1 10x 3' v3

Mus musculus

Pituitary gland cell

Normal

10x 3' v2

Mus musculus

Kidney loop of henle thick ascending limb epithelial cell Kidney interstitial fibroblast Leukocyte Kidney proximal convoluted tubule epithelial cell Macula densa epithelial cell Podocyte Kidney collecting duct principal cell Macrophage Blood vessel smooth muscle cell Endothelial cell Kidney collecting duct intercalated cell Mesangial cell Kidney granular cell Kidney distal convoluted tubule epithelial cell

Kidney

6-month-old stage

Autosomal dominant polycystic kidney disease

Male

Slide-seqv2

Drosophila melanogaster

Male germline cell Neuron Tracheolar cell Neuron Muscle cell Fat cell Epithelial cell Nociceptive neuron Female germline cell Hemocyte Sensory neuron Gustatory receptor neuron Oenocyte Somatic precursor cell Mechanosensory neuron Pheromone-sensing neuron Glial cell

Wing

Day 5 of adulthood

Normal

Female Male

10x 3' v3

Homo sapiens

Activated cd8-positive, alpha-beta t cell Plasmacytoid dendritic cell Natural killer cell Naive thymus-derived cd4-positive, alpha-beta t cell Erythroid lineage cell Innate lymphoid cell Effector memory cd8-positive, alpha-beta t cell Regulatory t cell Cd4-positive, alpha-beta memory t cell Naive b cell Memory b cell Gamma-delta t cell Cd4-positive, alpha-beta cytotoxic t cell Monocyte Platelet Naive thymus-derived cd8-positive, alpha-beta t cell Mature b cell Cd16-negative, cd56-bright natural killer cell, human Cd14-positive monocyte Hematopoietic precursor cell Activated cd4-positive, alpha-beta t cell Cd4-negative, cd8-negative, alpha-beta intraepithelial t cell Plasmablast Effector memory cd4-positive, alpha-beta t cell Cd141-positive myeloid dendritic cell Cd8-positive, alpha-beta memory t cell Mucosal invariant t cell Cd16-positive, cd56-dim natural killer cell, human Cd1c-positive myeloid dendritic cell

Blood

Fifth decade stage Adult stage Young adult stage Prime adult stage

Visceral leishmaniasis Normal Hiv infectious disease Leishmaniasis

Male

10x 5' v1

Cell

Mus musculus

Kidney loop of henle thick ascending limb epithelial cell Kidney interstitial fibroblast Leukocyte Kidney proximal convoluted tubule epithelial cell Macula densa epithelial cell Podocyte Kidney collecting duct principal cell Macrophage Blood vessel smooth muscle cell Endothelial cell Kidney collecting duct intercalated cell Mesangial cell Kidney granular cell Kidney distal convoluted tubule epithelial cell

Kidney

13-week-old stage

Diabetic kidney disease

Male

Slide-seqv2

Callithrix jacchus

Neuron

Basal forebrain Central amygdaloid nucleus

Prime adult stage

Normal

Female Male

10x 3' v3

Nucleus

Callithrix jacchus

Gabaergic neuron

Medial amygdaloid nucleus Amygdala Lateral amygdaloid nucleus

Prime adult stage

Normal

Female Male

10x 3' v3

Nucleus