Homo sapiens

Astrocyte Oligodendrocyte precursor cell Oligodendrocyte Leukocyte Vascular associated smooth muscle cell Fibroblast Pericyte Endothelial cell Neuron Central nervous system macrophage

Lateral posterior nucleus of thalamus

42-year-old stage 29-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Endothelial cell of lymphatic vessel Leukocyte Stromal cell Pericyte Endothelial cell Smooth muscle cell

Ovary

70-year-old stage 62-year-old stage 65-year-old stage 58-year-old stage 72-year-old stage

Normal

Female

10x 3' v3 Drop-seq

Cell

Homo sapiens

L2/3-6 intratelencephalic projecting glutamatergic neuron

Middle temporal gyrus

80-year-old stage 85-year-old stage 82-year-old stage 70-year-old stage 77-year-old stage 50-year-old stage 86-year-old stage 60-year-old stage 80 year-old and over stage 89-year-old stage 65-year-old stage 75-year-old stage Adult stage 78-year-old stage 68-year-old stage 72-year-old stage 88-year-old stage 84-year-old stage 69-year-old stage 43-year-old stage 29-year-old stage 87-year-old stage 81-year-old stage 83-year-old stage

Normal Dementia

Female Male

10x 3' v3 10x multiome

Nucleus

Homo sapiens

Astrocyte Oligodendrocyte precursor cell Oligodendrocyte Leukocyte Bergmann glial cell Vascular associated smooth muscle cell Fibroblast Ependymal cell Pericyte Endothelial cell Neuron Central nervous system macrophage

Dorsal tegmental nucleus

50-year-old stage 42-year-old stage 29-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Malignant cell

Hepatic flexure of colon Rectum Liver Chest wall Caecum Lung Transverse colon Peritoneum Sigmoid colon Descending colon

70-year-old stage 50-year-old stage 62-year-old stage 52-year-old stage 60-year-old stage 44-year-old stage 48-year-old stage 64-year-old stage 45-year-old stage 74-year-old stage 65-year-old stage 40-year-old stage 75-year-old stage 37-year-old stage 78-year-old stage 68-year-old stage 49-year-old stage 35-year-old stage 53-year-old stage 73-year-old stage 39-year-old stage 41-year-old stage 55-year-old stage

Colorectal cancer

Female Male

10x 3' v3

Cell

Homo sapiens

Cd4-positive helper t cell B cell Cd8-positive, alpha-beta t cell Dendritic cell Regulatory t cell Myeloid cell

Lymph node

Adult stage

Normal

Slide-seqv2

Homo sapiens

Cardiac ventricle fibroblast

Apex of heart Heart left ventricle

19-year-old stage 70-year-old stage 21-year-old stage 32-year-old stage 52-year-old stage 64-year-old stage 25-year-old stage Eighth decade stage 27-year-old stage 28-year-old stage Fifth decade stage 31-year-old stage 61-year-old stage 49-year-old stage 30-year-old stage 24-year-old stage Seventh decade stage 26-year-old stage Third decade stage 29-year-old stage 38-year-old stage 55-year-old stage Sixth decade stage

Normal Myocarditis

Female Male

10x 3' v3 10x 3' v2

Nucleus

Mus musculus

Kidney loop of henle thick ascending limb epithelial cell Kidney granular cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney interstitial fibroblast Kidney collecting duct principal cell Macula densa epithelial cell Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Podocyte Endothelial cell Mesangial cell Kidney proximal convoluted tubule epithelial cell

Kidney

13-week-old stage

Diabetic kidney disease

Male

Slide-seqv2

Homo sapiens

Off-bipolar cell On-bipolar cell

Peripheral region of retina Fovea centralis

60-year-old stage 64-year-old stage 74-year-old stage 65-year-old stage 78-year-old stage 53-year-old stage 69-year-old stage

Normal

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Astrocyte Oligodendrocyte precursor cell Oligodendrocyte Leukocyte Vascular associated smooth muscle cell Fibroblast Ependymal cell Pericyte Endothelial cell Neuron Central nervous system macrophage

Pretectal region

42-year-old stage 29-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Adipocyte

Omental fat pad Subcutaneous adipose tissue

57-year-old stage 36-year-old stage 58-year-old stage 68-year-old stage 51-year-old stage 35-year-old stage 53-year-old stage 73-year-old stage 24-year-old stage 29-year-old stage 41-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Cardiac endothelial cell Cd4-positive, alpha-beta t cell Platelet Macrophage Mesothelial cell Ventricular cardiac muscle cell Mast cell Neutrophil Monocyte Regular atrial cardiac myocyte Pericyte B cell Cd8-positive, alpha-beta t cell Plasma cell Erythrocyte Fibroblast of cardiac tissue Mature nk t cell T cell Plasmacytoid dendritic cell Smooth muscle cell Neuron Natural killer cell

Cardiac ventricle Right cardiac atrium Cardiac atrium Heart right ventricle Heart

60-year-old stage 45-year-old stage 74-year-old stage 59-year-old stage 56-year-old stage 61-year-old stage

Normal

Female Male

Smart-seq2 10x 3' v3

Cell