Homo sapiens

Preadipocyte

Omental fat pad Subcutaneous adipose tissue

57-year-old stage 71-year-old stage 36-year-old stage 59-year-old stage 54-year-old stage 58-year-old stage 68-year-old stage 51-year-old stage 49-year-old stage 35-year-old stage 53-year-old stage 73-year-old stage 24-year-old stage 29-year-old stage 41-year-old stage

Normal

Female Male

10x 3' v3 Drop-seq

Nucleus Cell

Homo sapiens

Macrophage Mast cell Neutrophil Monocyte Megakaryocyte Dendritic cell, human Conventional dendritic cell Trem2-positive macrophage Plasmacytoid dendritic cell, human Erythrocyte Eosinophil Neutrophil progenitor cell Immature neutrophil Langerhans cell Mature neutrophil

Epithelium of esophagus Gingiva Lamina propria of mucosa of colon Body of stomach Duodenal epithelium Ileum Rectum Ileum lamina propria Mesenteric lymph node Parotid gland Epithelium of rectum Caecum Small intestine Esophagus Colonic epithelium Epithelium of stomach Jejunum Transverse colon Labial gland Epithelium of small intestine Pyloric antrum Sigmoid colon Periodontium Duodenum Ileal epithelium Pylorus Colon Intestine Descending colon Ascending colon Stomach Rectosigmoid junction Buccal mucosa Vermiform appendix Colonic mucosa

80-year-old stage 9th week post-fertilization stage 85-year-old stage 66-year-old stage 70-year-old stage Young adult stage Fourth decade stage 77-year-old stage 13th week post-fertilization stage 12th week post-fertilization stage 21-year-old stage 32-year-old stage 50-year-old stage 86-year-old stage 57-year-old stage 76-year-old stage 10th week post-fertilization stage 62-year-old stage Prime adult stage 46-year-old stage 52-year-old stage 60-year-old stage 22-year-old stage Carnegie stage 22 Juvenile stage (5-14 yo) 44-year-old stage 48-year-old stage 45-year-old stage 74-year-old stage 33-year-old stage 65-year-old stage 67-year-old stage Embryonic stage 2-year-old stage Eighth decade stage 75-year-old stage 23-year-old stage 37-year-old stage Adult stage 11th week post-fertilization stage 14-year-old stage 21st week post-fertilization stage 6-year-old stage 28-year-old stage 19th week post-fertilization stage 63-year-old stage 17th week post-fertilization stage 59-year-old stage 54-year-old stage Fifth decade stage 31-year-old stage 2-month-old stage 15th week post-fertilization stage 56-year-old stage 58-year-old stage Pediatric stage 68-year-old stage 61-year-old stage 34-year-old stage Carnegie stage 19 51-year-old stage 35-year-old stage 16th week post-fertilization stage 10-year-old stage 72-year-old stage 30-year-old stage 24-year-old stage 13-year-old stage 18th week post-fertilization stage Seventh decade stage 26-year-old stage 84-year-old stage 12-year-old stage 39-year-old stage Newborn stage (0-28 days) 4-year-old stage Carnegie stage 17 9-year-old stage 69-year-old stage Third decade stage 43-year-old stage 5-year-old stage 29-year-old stage 87-year-old stage 41-year-old stage Carnegie stage 18 81-year-old stage 55-year-old stage Carnegie stage 16 Sixth decade stage 11-year-old stage

Ulcerative colitis Inflammatory bowel disease Normal Crohn disease Colorectal cancer Gastric cancer

Female Male

10x 5' v2 10x 5' v1 10x 3' v3 10x 5' transcription profiling 10x 3' v1 10x 3' v2

Cell

Homo sapiens

Schwann cell Corneal epithelial cell Endothelial cell of lymphatic vessel Lymphocyte Macrophage Mast cell Basal cell Ciliary muscle cell Fibroblast Blood vessel endothelial cell Pericyte Endothelial cell Corneal endothelial cell Conjunctival epithelial cell Melanocyte Goblet cell

Eye trabecular meshwork Corneo-scleral junction

66-year-old stage 65-year-old stage 47-year-old stage 30-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Astrocyte Oligodendrocyte precursor cell Oligodendrocyte Leukocyte Bergmann glial cell Vascular associated smooth muscle cell Fibroblast Ependymal cell Pericyte Endothelial cell Neuron Central nervous system macrophage Choroid plexus epithelial cell

Cerebellar nuclear complex

50-year-old stage 42-year-old stage 29-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Glutamatergic neuron Glial cell Gabaergic neuron

Parietal lobe Temporal lobe Primary visual cortex Prefrontal cortex

7-month-old stage

Normal

Drop-seq

Nucleus

Homo sapiens

Cd8-positive, alpha-beta thymocyte Cd4-positive, alpha-beta t cell Cd4-positive, alpha-beta thymocyte Immature alpha-beta t cell Mature alpha-beta t cell Cd8-positive, alpha-beta t cell

Venous blood Bronchopulmonary lymph node Lower lobe of left lung Bone marrow

52-year-old stage 65-year-old stage

Normal

Male

10x 3' v2

Cell

Mus musculus

Endo-epithelial cell Intestine goblet cell Extraembryonic cell Intestinal enteroendocrine cell

Embryo

Theiler stage 23 Theiler stage 24 Theiler stage 21 Theiler stage 13 Theiler stage 25 Theiler stage 17 Theiler stage 16 Theiler stage 26 Theiler stage 12 Theiler stage 18 Theiler stage 20 Theiler stage 19 Theiler stage 27 Theiler stage 14 Theiler stage 15 Theiler stage 22

Normal

Female Male

Sci-rna-seq3

Nucleus

Homo sapiens

Retinal rod cell Astrocyte Retinal cone cell Off-bipolar cell On-bipolar cell Microglial cell Mueller cell Amacrine cell Retinal ganglion cell Retina horizontal cell Rod bipolar cell

Retina

85-year-old stage 74-year-old stage 87-year-old stage 55-year-old stage

Normal

Female Male

10x multiome

Nucleus

Homo sapiens

Retinal rod cell Astrocyte Retinal cone cell Off-bipolar cell On-bipolar cell Microglial cell Mueller cell Amacrine cell Retinal ganglion cell Retina horizontal cell Rod bipolar cell

Normal

10x multiome

Homo sapiens

Classical monocyte Non-classical monocyte Macrophage Alveolar macrophage Dendritic cell, human Conventional dendritic cell

Blood Ileum Thymus Mesenteric lymph node Liver Spleen Skeletal muscle tissue Caecum Lung Lamina propria Transverse colon Omentum Sigmoid colon Duodenum Bone marrow Jejunal epithelium Thoracic lymph node

Eighth decade stage Seventh decade stage Sixth decade stage

Normal

Female Male

10x 5' v2 10x 5' v1 10x 3' v3

Cell

Homo sapiens

Luminal hormone-sensing cell of mammary gland Macrophage Luminal adaptive secretory precursor cell of mammary gland Adipocyte Fibroblast Endothelial cell T cell Basal-myoepithelial cell of mammary gland

Breast Upper outer quadrant of breast

Adult stage

Normal

Female

10x multiome

Nucleus

Mus musculus

Preadipocyte

Epididymal fat pad Periovarian fat pad Inguinal fat pad

19-week-old stage

Normal

Female Male

10x 3' v3

Nucleus