Homo sapiens

Cardiac muscle cell Fibroblast of cardiac tissue Myeloid cell Endothelial cell Adipocyte Cardiac neuron Mural cell Mast cell Lymphocyte

Heart left ventricle Apex of heart Interventricular septum Heart right ventricle

Fourth decade stage Eighth decade stage Postnatal stage Pediatric stage Fifth decade stage Sixth decade stage Seventh decade stage Third decade stage

Non-compaction cardiomyopathy Normal Dilated cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy

Male Female

10x 3' v3 10x 3' v2

Nucleus

Homo sapiens

Monocyte Macrophage Endothelial cell of artery B cell Fibroblast Blood vessel smooth muscle cell Pericyte Endothelial cell of arteriole Non-myelinating schwann cell Natural killer cell Fenestrated endothelial cell Classical monocyte Melanocyte Dendritic cell Retinal pigment epithelial cell Plasma cell Platelet T cell Endothelial cell of venule Mast cell Myelinating schwann cell

Chorioretinal region

69-year-old stage 77-year-old stage 80 year-old and over stage 81-year-old stage 12th week post-fertilization stage 47-year-old stage 25-year-old stage 64-year-old stage 10-year-old stage Newborn stage (0-28 days) 50-year-old stage 68-year-old stage 82-year-old stage 63-year-old stage 86-year-old stage 15th week post-fertilization stage 21-year-old stage 11th week post-fertilization stage 65-year-old stage 58-year-old stage 32-year-old stage 11-year-old stage 14th week post-fertilization stage 30-year-old stage 71-year-old stage 60-year-old stage 18th week post-fertilization stage 34-year-old stage 17th week post-fertilization stage 16-year-old stage 62-year-old stage 72-year-old stage 24th week post-fertilization stage 43-year-old stage 27-year-old stage 21st week post-fertilization stage 46-year-old stage 17-year-old stage 53-year-old stage 13th week post-fertilization stage

Normal

Male Female

10x 3' v3 10x 5' v2

Nucleus

Homo sapiens

B cell Hematopoietic stem cell Gamma-delta t cell Blood cell Cd8-positive, alpha-beta t cell Natural killer cell Megakaryocyte-erythroid progenitor cell Plasmablast Classical monocyte Enucleated reticulocyte Dendritic cell Non-classical monocyte Mucosal invariant t cell Double negative t regulatory cell Cd4-positive, alpha-beta t cell Mast cell Double-positive, alpha-beta thymocyte

Blood

90 year-old and over stage Fourth decade stage Young adult stage Eighth decade stage Ninth decade stage Fifth decade stage Sixth decade stage Seventh decade stage

Normal Covid-19 Influenza

Male Female

10x 5' v1

Cell

Homo sapiens

Monocyte Macrophage Progenitor cell B cell Corneal endothelial cell Conjunctival epithelial cell Fibroblast Pericyte Blood vessel endothelial cell Endothelial cell of lymphatic vessel Keratocyte Endothelial cell Schwann cell Smooth muscle cell Leukocyte Melanocyte Epithelial cell Mast cell Myelinating schwann cell Lymphocyte

Ocular surface region Tunica fibrosa of eyeball Corneal endothelium Sclera Substantia propria of cornea Corneal epithelium Cornea Corneo-scleral junction

69-year-old stage 83-year-old stage 77-year-old stage 22-year-old stage 87-year-old stage 25-year-old stage 90 year-old and over stage 64-year-old stage 1-year-old stage 10-year-old stage Newborn stage (0-28 days) Eighth decade stage 67-year-old stage 86-year-old stage 15th week post-fertilization stage 48-year-old stage 13-year-old stage 11th week post-fertilization stage Postnatal stage 65-year-old stage 19th week post-fertilization stage 32-year-old stage 11-year-old stage 14th week post-fertilization stage 39-year-old stage 41-year-old stage 18th week post-fertilization stage 20th week post-fertilization stage 34-year-old stage 17th week post-fertilization stage 51-year-old stage 45-year-old stage 61-year-old stage 16-year-old stage 23rd week post-fertilization stage 74-year-old stage 62-year-old stage 75-year-old stage 72-year-old stage 33-year-old stage 43-year-old stage 27-year-old stage 21st week post-fertilization stage 2-year-old stage 55-year-old stage 53-year-old stage 13th week post-fertilization stage 70-year-old stage 22nd week post-fertilization stage 84-year-old stage

Normal

Male Female

10x 3' v3 10x 3' v2 10x multiome

Cell Nucleus

Mus musculus

Macrophage Conventional dendritic cell Naive b cell T-helper 17 cell Cytotoxic t cell Common myeloid progenitor Marginal zone b cell of lymph node Follicular b cell Germinal center b cell Naive t cell Neutrophil Plasmablast Leukocyte Mucosal invariant t cell Cycling t cell Basophil Group 3 innate lymphoid cell Plasma cell Natural t-regulatory cell Plasmacytoid dendritic cell Centrocyte Bm3 b cell Mature nk t cell Transitional stage b cell Eosinophil T cell Lymphoid tissue–inducer cell Group 2 innate lymphoid cell Cd103-positive dendritic cell

Normal

10x 3' v3

Homo sapiens

Neuron Pulmonary alveolar type 1 cell M cell of gut Type b pancreatic cell Intestinal tuft cell Club cell Hepatic stellate cell Stromal cell Pericyte Pancreatic epsilon cell Paneth cell Goblet cell Pancreatic ductal cell Epithelial cell of pancreas Endothelial cell Schwann cell Smooth muscle cell Enteroendocrine cell Stem cell Hepatoblast Lung secretory cell Acinar cell Thymocyte Epithelial cell Neuroendocrine cell Enterocyte Best4+ enterocyte Mesothelial cell Pancreatic d cell Pancreatic a cell Epithelial cell of stomach Ciliated cell Luminal cell of prostate epithelium Mesodermal cell Interstitial cell of cajal Hematopoietic cell Kupffer cell Basal cell Pulmonary alveolar type 2 cell Colon epithelial cell

Colon Nasopharynx Corpus Liver Common bile duct Bronchus Gallbladder Salivary gland epithelium Pancreas Ileum Intrahepatic bile duct Pyloric antrum Lung epithelium Intestine Biliary system Stomach Lung Thyroid gland Prostate gland Alveolar sac Duodenum

Normal

Cel-seq2 Smart-seq Sort-seq 10x 3' v3 Seq-well s3 10x 3' v2 10x multiome 10x 5' v1

Cell Nucleus

Homo sapiens

Blood vessel endothelial cell Luminal epithelial cell of mammary gland Endothelial cell of lymphatic vessel Perivascular cell Leukocyte Basal-myoepithelial cell of mammary gland Luminal adaptive secretory precursor cell of mammary gland Mural cell Mammary gland epithelial cell Fibroblast of mammary gland Luminal hormone-sensing cell of mammary gland

Breast

23-year-old stage 56-year-old stage 25-year-old stage 36-year-old stage 38-year-old stage 40-year-old stage 63-year-old stage 48-year-old stage 21-year-old stage 31-year-old stage 19-year-old stage 20-year-old stage 28-year-old stage 65-year-old stage 58-year-old stage 30-year-old stage 39-year-old stage 41-year-old stage 34-year-old stage 45-year-old stage 62-year-old stage 33-year-old stage 59-year-old stage 29-year-old stage 57-year-old stage 27-year-old stage 46-year-old stage 35-year-old stage 37-year-old stage 24-year-old stage 52-year-old stage 55-year-old stage 53-year-old stage

Normal

Female

10x 3' v3

Cell

Mus musculus Homo sapiens

Oligodendrocyte precursor cell Macrophage Inhibitory interneuron Cerebellar neuron Obsolete excitatory neuron Fibroblast Cerebellar golgi cell Endothelial cell Astrocyte of the cerebellum Interneuron Microglial cell Oligodendrocyte Endothelial stalk cell Bergmann glial cell Purkinje cell Ependymal cell Cerebellar granule cell

Normal

10x 3' v3

Homo sapiens

Monocyte B cell Conventional dendritic cell Hematopoietic stem cell Common myeloid progenitor Erythroid lineage cell Granulocyte monocyte progenitor cell Natural killer cell Megakaryocyte-erythroid progenitor cell Promonocyte Plasma cell Plasmacytoid dendritic cell Pro-b cell T cell

Bone marrow

23-year-old stage 19-month-old stage 56-year-old stage 77-year-old stage 81-year-old stage 8-year-old stage 22-year-old stage 47-year-old stage 5-year-old stage 64-year-old stage 79-year-old stage 1-year-old stage 10-year-old stage 6-year-old stage 50-year-old stage 36-year-old stage 38-year-old stage 66-year-old stage 8-month-old stage 78-year-old stage 67-year-old stage 63-year-old stage 7-year-old stage 48-year-old stage 21-year-old stage 13-year-old stage 31-year-old stage 19-year-old stage 20-year-old stage 54-year-old stage 28-year-old stage 80-year-old stage 65-year-old stage 58-year-old stage 32-year-old stage 42-year-old stage 11-year-old stage 30-year-old stage 71-year-old stage 60-year-old stage 39-year-old stage 76-year-old stage 41-year-old stage 14-year-old stage 51-year-old stage 45-year-old stage 2-month-old stage 26-year-old stage 85-year-old stage 61-year-old stage 9-year-old stage 16-year-old stage 12-year-old stage 74-year-old stage 62-year-old stage 75-year-old stage 72-year-old stage 15-year-old stage 33-year-old stage 43-year-old stage 59-year-old stage 29-year-old stage Adult stage 57-year-old stage 46-year-old stage 35-year-old stage 17-year-old stage 2-year-old stage 73-year-old stage 18-month-old stage 24-year-old stage 52-year-old stage 55-year-old stage 53-year-old stage 70-year-old stage 44-year-old stage 4-year-old stage 3-year-old stage 84-year-old stage

Normal Myeloid leukemia

Male Female

Smart-seq2 Seq-well Sort-seq 10x 3' v3 10x transcription profiling 10x 5' v2 10x 3' v2 10x 3' v1 10x 5' v1

Cell

Homo sapiens

Naive thymus-derived cd4-positive, alpha-beta t cell Memory regulatory t cell Double negative thymocyte Naive regulatory t cell Effector memory cd4-positive, alpha-beta t cell Cd4-positive, alpha-beta memory t cell Central memory cd4-positive, alpha-beta t cell Cd8-positive, alpha-beta regulatory t cell Memory ccr4-positive regulatory t cell T cell

Blood

56-year-old stage 25-year-old stage 64-year-old stage 36-year-old stage 63-year-old stage 31-year-old stage 28-year-old stage 65-year-old stage 58-year-old stage 32-year-old stage 11-year-old stage 30-year-old stage 60-year-old stage 34-year-old stage 26-year-old stage 61-year-old stage 12-year-old stage 62-year-old stage 33-year-old stage 59-year-old stage 29-year-old stage 57-year-old stage 27-year-old stage 35-year-old stage 55-year-old stage

Cytomegalovirus infection Normal

Male Female

10x 3' v3

Cell

Homo sapiens

Pulmonary alveolar type 1 cell B cell Fibroblast Myeloid cell Endothelial cell Smooth muscle cell Epithelial cell Lymph node lymphatic vessel endothelial cell Apoptosis fated cell Mast cell Lymphocyte Pulmonary alveolar type 2 cell

Pulmonary systemic sclerosis Normal Chronic obstructive pulmonary disease Pulmonary fibrosis

10x 3' v3 10x 3' v2 10x 3' v1

Homo sapiens

Macrophage Endothelial cell of artery Conventional dendritic cell Fibroblast Iga plasma cell Naive b cell Pericyte Gamma-delta t cell Alternatively activated macrophage Luminal epithelial cell of mammary gland Regulatory t cell Myeloid cell Endothelial cell of lymphatic vessel Myeloid dendritic cell Natural killer cell Capillary endothelial cell Effector memory cd4-positive, alpha-beta t cell Neutrophil Activated cd8-positive, alpha-beta t cell Classical monocyte Cd8-positive, alpha-beta memory t cell Inflammatory macrophage Igg plasma cell Effector memory cd8-positive, alpha-beta t cell Non-classical monocyte Cd4-positive helper t cell Vascular associated smooth muscle cell Cd4-positive, alpha-beta t cell Mammary gland epithelial cell Activated cd4-positive, alpha-beta t cell Unswitched memory b cell Plasmacytoid dendritic cell Mature nk t cell T cell Mast cell Basal cell Vein endothelial cell Class switched memory b cell Lymphocyte

Breast

Adult stage Prime adult stage

Normal

Female

10x 3' v3 10x 3' v2

Cell