Mus musculus

Obsolete inhibitory neuron Oligodendrocyte Microglial cell Brain microvascular endothelial cell Obsolete excitatory neuron Astrocyte

Normal

10x 3' v2

Homo sapiens

T cell Mononuclear leukocyte Muscle cell Blood vessel endothelial cell Natural killer cell Endothelial cell of lymphatic vessel Pulmonary alveolar epithelial cell Mast cell Plasmacytoid dendritic cell Lung multiciliated epithelial cell Lung macrophage Cd8-positive, alpha-beta cytotoxic t cell Regulatory t cell Plasma cell Cd4-positive, alpha-beta t cell B cell Monocyte Conventional dendritic cell Fibroblast Dendritic cell

Lung parenchyma

Sixth decade stage Fifth decade stage Seventh decade stage Eighth decade stage

Normal

Female Male

10x 3' v2

Cell

Drosophila melanogaster

Proximal medullary amacrine neuron Dn1 neuron Adult dopaminergic neuron Adult kenyon cell Subperineurial glial cell Cchamide-1 neuron Adult insulin secreting cell of pars intercerebralis Obsolete neurosecretory neuron Lamina wide-field 2 neuron Pacemaker neuron Adult tyraminergic neuron Adult optic chiasma glial cell Adult ccap neuron Adult gamma kenyon cell Centrifugal neuron c2 Peptidergic neuron Adult corazonin neuron Proximal medullary amacrine neuron pm4 Adult serotonergic neuron Adult mushroom body output neuron Adult capability neuron Adult optic lobe neuron Neural cell Lnv neuron Adult myoinhibitory peptide neuron Astrocyte-like glial cell Medulla tangential neuron mt1 Adult ensheathing glial cell Transmedullary neuron tm9 Adult hugin neuron Transmedullary neuron tm5c Photoreceptor cell Lamina monopolar neuron l2 Distal medullary amacrine neuron dm9 Lamina wide-field 1 neuron Distal medullary amacrine neuron Adult neuron Proximal medullary amacrine neuron pm3 Lamina monopolar neuron l3 Transmedullary neuron tm5 Lamina monopolar neuron Transmedullary y neuron tmy14 Sugar-sensing neuron of the adult brain Adult brain perineurial glial cell Centrifugal neuron c3 Adult olfactory projection neuron Adult plasmatocyte Medulla tangential neuron mt3 Central nervous system neuron Medial antennal lobe tract projection neuron Adult dopaminergic pam neuron Medulla intrinsic neuron mi1 Transmedullary neuron Adult octopaminergic neuron Adult brain cell body glial cell Adult peptidergic neuron Adult antennal lobe projection neuron adpn Itp neuron Lamina monopolar neuron l1 Medulla tangential neuron mt2

Brain

Day 15 of adulthood Day 3 of adulthood Day 9 of adulthood Day 30 of adulthood Day 0 of adulthood Day 50 of adulthood Day 1 of adulthood Day 6 of adulthood

Normal

Mixed sex

10x genomics v2 Illumina

Homo sapiens

T cell Lung resident memory cd8-positive, cd103-positive, alpha-beta t cell Neutrophil Club cell Cd1c-positive myeloid dendritic cell Natural killer cell Endothelial cell of lymphatic vessel Gamma-delta t cell Neuroendocrine cell Microvascular endothelial cell Mast cell Exhausted t cell Platelet Cd141-positive myeloid dendritic cell Serous secreting cell Basal cell Endothelial cell of artery Capillary endothelial cell Classical monocyte Ionocyte Smooth muscle cell Intermediate monocyte Plasmacytoid dendritic cell Goblet cell Naive thymus-derived cd8-positive, alpha-beta t cell Macrophage Memory b cell Innate lymphoid cell Regulatory t cell Pulmonary alveolar type 1 cell Helper t cell Effector t cell Plasma cell Vein endothelial cell T follicular helper cell Alveolar adventitial fibroblast Mesothelial cell Ciliated epithelial cell Alveolar capillary type 2 endothelial cell Pericyte Progenitor cell Naive thymus-derived cd4-positive, alpha-beta t cell Mucosal invariant t cell Alveolar type 1 fibroblast cell Mucus secreting cell Naive b cell Myofibroblast cell Fibroblast Dendritic cell Pulmonary alveolar type 2 cell Non-classical monocyte

Lung

13-year-old stage 17-year-old stage 15-year-old stage 41-year-old stage 27-year-old stage

Acute graft versus host disease Normal

Female Male

10x 5' v2 10x 5' v1 10x 3' v3

Cell

Homo sapiens

Amacrine cell

Peripheral region of retina Macula lutea proper Fovea centralis

65-year-old stage 84-year-old stage 78-year-old stage 73-year-old stage 83-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

T cell Central nervous system macrophage Natural killer cell Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Committed oligodendrocyte precursor Dentate gyrus granule cell Cerebellar granule cell Hippocampal ca1-3 neuron Lamp5 lhx6 neuron Eccentric medium spiny neuron Pvalb chandelier gabaergic interneuron Medial ganglionic eminence derived interneuron Ependymal cell Microglial cell B cell Pericyte Cerebral cortex neuron Neuron Monocyte Intratelencephalic-projecting glutamatergic cortical neuron Caudal ganglionic eminence derived interneuron Vascular associated smooth muscle cell Sst chodl gabaergic interneuron Astrocyte Fibroblast Medium spiny neuron Hippocampal ca4 neuron

Dentate gyrus of hippocampal formation

42-year-old stage 29-year-old stage 50-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Lamp5 gabaergic interneuron

Dorsolateral prefrontal cortex

69-year-old stage 75-year-old stage 42-year-old stage 89-year-old stage 87-year-old stage 85-year-old stage 88-year-old stage 68-year-old stage 29-year-old stage 84-year-old stage 82-year-old stage 50-year-old stage 80-year-old stage 72-year-old stage 81-year-old stage 80 year-old and over stage 77-year-old stage 86-year-old stage 70-year-old stage 78-year-old stage 83-year-old stage

Normal Dementia

Female Male

10x multiome 10x 3' v3

Nucleus

Macaca mulatta

Oligodendrocyte precursor cell

Dorsolateral prefrontal cortex Brodmann (1909) area 19 Medial dorsal nucleus of thalamus Primary visual cortex Ventral lateral nucleus of thalamus Inferior temporal gyrus Medulla oblongata Prefrontal cortex Midbrain Entorhinal cortex Nucleus accumbens Cerebrocerebellum Primary somatosensory cortex Primary auditory cortex Primary motor cortex Inferior parietal cortex Head of caudate nucleus Corpus callosum Hippocampal formation Perirhinal cortex Pons Cerebellar vermis Anterior cingulate cortex Superior temporal sulcus Superior parietal cortex Lateral geniculate body Amygdala

Juvenile stage Prime adult stage

Normal

Female Male

Sci-rna-seq3

Nucleus

Homo sapiens

Classical monocyte

Blood

37-year-old stage 75-year-old stage Sixth decade stage 53-year-old stage 61-year-old stage 54-year-old stage 68-year-old stage 48-year-old stage 39-year-old stage 29-year-old stage 38-year-old stage Fifth decade stage 84-year-old stage 82-year-old stage Third decade stage 80 year-old and over stage 49-year-old stage Seventh decade stage 59-year-old stage Adult stage 67-year-old stage 62-year-old stage 70-year-old stage 46-year-old stage 60-year-old stage 78-year-old stage 36-year-old stage Fourth decade stage 63-year-old stage Eighth decade stage 47-year-old stage 73-year-old stage 27-year-old stage

Covid-19 Normal

Female Male

Seq-well 10x 3' v3 10x 3' v2

Cell

Homo sapiens

Germinal center b cell Pro-b cell Precursor b cell Lymphocyte Memory b cell Plasmablast Plasma cell Naive b cell

Lung Thymus Duodenum Jejunal epithelium Caecum Skeletal muscle tissue Ileum Liver Thoracic lymph node Spleen Transverse colon Jejunum lamina propria Omentum Blood Bone marrow Sigmoid colon Mesenteric lymph node

Sixth decade stage 56-year-old stage Seventh decade stage 67-year-old stage Eighth decade stage

Normal

Female Male

10x 5' v2 10x 5' v1 10x 3' v3

Cell

Mus musculus

T cell Endocardial cell Club cell Granulocyte Cardiac endothelial cell Hepatocyte Stromal cell Ciliated cell Natural killer cell Erythrocyte Kidney tubule cell Endothelial cell Basal cell of epithelium of trachea Neuroendocrine cell Mast cell Tracheal epithelial cell Basal cell Bladder cell Leukocyte Smooth muscle cell Skeletal muscle satellite cell Lung macrophage Chondroblast Basal cell of epidermis Splenic macrophage Macrophage Basal cell of urothelium Fenestrated endothelial cell Lung endothelial cell Keratinocyte Hematopoietic stem cell Obsolete somatic cell Mesenchymal cell Luminal cell of lactiferous duct Mesothelial cell Ciliated epithelial cell Cardiac muscle cell Kidney collecting duct cell B cell Mesenchymal stem cell Fraction a pre-pro b cell Monocyte Fibroblast Dendritic cell Fibroblast of cardiac tissue Pulmonary alveolar type 2 cell

Lung Thymus Trachea Liver Urinary bladder Heart Tongue Adult mammalian kidney Mammary gland Limb muscle Spleen Bone marrow

3-month-old stage

Normal

Female Male

10x genomics v2

Homo sapiens

T cell Stromal cell Platelet Primitive red blood cell Macrophage Plasma cell Monocyte Conventional dendritic cell

Bone marrow

66-year-old stage 61-year-old stage 68-year-old stage 84-year-old stage 51-year-old stage 57-year-old stage 58-year-old stage 59-year-old stage Adult stage 67-year-old stage 64-year-old stage 62-year-old stage 40-year-old stage

Plasma cell myeloma Normal

Female Male

Mars-seq

Cell