Homo sapiens

Erythroid lineage cell Hepatocyte Double negative thymocyte Megakaryocyte Vascular associated smooth muscle cell Epithelial cell Megakaryocyte progenitor cell Mesothelial cell

Liver

16th week post-fertilization stage

Normal

Visium spatial gene expression v1

Homo sapiens

Hepatocyte Centrilobular region hepatocyte Intrahepatic cholangiocyte Periportal region hepatocyte Blood cell

Caudate lobe of liver

Prime adult stage

Primary sclerosing cholangitis

Female

Visium spatial gene expression v1

Homo sapiens

Iga plasma cell Cd4-positive, alpha-beta t cell Endothelial cell Fibroblast Acinar cell of salivary gland

Labial gland

48-year-old stage 40-year-old stage

Sjogren syndrome

Female

Visium spatial gene expression v1

Homo sapiens

Cardiac muscle myoblast Neuronal receptor cell Pericyte Cardiac endothelial cell Lymphoid lineage restricted progenitor cell Fibroblast of cardiac tissue Immature innate lymphoid cell Smooth muscle myoblast

Heart left ventricle

43-year-old stage

Myocardial infarction

Female

Visium spatial gene expression v1

Homo sapiens

Natural killer cell Naive thymus-derived cd4-positive, alpha-beta t cell Kidney loop of henle thick ascending limb epithelial cell B cell Naive b cell Podocyte Pericyte Iga plasma cell Conventional dendritic cell Endothelial cell of lymphatic vessel Classical monocyte Cd4-positive, alpha-beta t cell Kidney collecting duct principal cell Macrophage Cd4-positive, cd25-positive, alpha-beta regulatory t cell Cd8-positive, alpha-beta t cell Igg plasma cell Kidney loop of henle ascending limb epithelial cell Endothelial cell Epithelial cell of proximal tubule segment 1 Collagen secreting cell Fibroblast Mast cell Epithelial cell of proximal tubule segment 3

Kidney

Sixth decade stage

Nonpapillary renal cell carcinoma

Male

Visium spatial gene expression v1

Homo sapiens

Mammary gland epithelial cell Adipocyte of breast B cell Pericyte Endothelial cell of lymphatic vessel Endothelial cell of vascular tree Luminal epithelial cell of mammary gland Fibroblast

Breast

Prime adult stage

Normal

Female

Visium spatial gene expression v1

Homo sapiens

Dendritic cell Iga plasma cell Duct epithelial cell Cd4-positive, alpha-beta t cell Macrophage Endothelial cell Fibroblast Acinar cell of salivary gland

Labial gland

64-year-old stage 56-year-old stage

Normal

Female Male

Visium spatial gene expression v1

Homo sapiens

Basal cell of epidermis Cell of skeletal muscle Pericyte Endothelial cell of vascular tree Suprabasal keratinocyte Chondrocyte Fibroblast

Nose skin

77-year-old stage

Normal

Male

Visium spatial gene expression v1

Homo sapiens

Goblet cell Regulatory t cell B cell Enterocyte Pericyte Iga plasma cell Malignant cell Smooth muscle cell Macrophage Cd8-positive, alpha-beta t cell Igg plasma cell Endothelial tip cell Inflammatory macrophage Transit amplifying cell of colon Endothelial stalk cell

Rectum

Eighth decade stage

Colorectal cancer

Male

Visium spatial gene expression v1

Homo sapiens

Schwann cell Basal cell of epidermis Pericyte Endothelial cell of lymphatic vessel Smooth muscle cell Macrophage Basal cell Endothelial cell of vascular tree Suprabasal keratinocyte Fibroblast

Skin of breast

42-year-old stage

Normal

Female

Visium spatial gene expression v1

Homo sapiens

Naive thymus-derived cd4-positive, alpha-beta t cell Innate lymphoid cell Endothelial cell of artery Regular ventricular cardiac myocyte Glial cell Pericyte Monocyte Smooth muscle cell Macrophage Fibroblast of cardiac tissue Smooth muscle cell of the pulmonary artery Vein endothelial cell Mast cell

Interventricular septum

Fifth decade stage

Normal

Female

Visium spatial gene expression v1

Mus musculus

Hepatocyte Hepatic stellate cell Endothelial cell of hepatic sinusoid Peritoneal macrophage Cholangiocyte B cell Conventional dendritic cell Endothelial cell of lymphatic vessel Neutrophil Kupffer cell Endothelial cell of periportal hepatic sinusoid Intermediate monocyte Erythrocyte Endothelial cell of pericentral hepatic sinusoid Vascular associated smooth muscle cell Hematopoietic stem cell Fibroblast

Liver

Young adult stage

Normal

Visium spatial gene expression v1