Mus musculus

Notochordal cell Spinal cord interneuron Paraxial cell Neurectodermal cell Gut endothelial cell Splanchnic mesodermal cell Hemangioblast Cardiac valve cell Endodermal cell Primitive red blood cell Midbrain dopaminergic neuron Anterior visceral endoderm cell Premigratory neural crest cell Mesodermal cell Neuroplacodal cell Surface ectodermal cell

Embryo

Theiler stage 14

Normal

Slide-seqv2

Mus musculus

Plasmacytoid dendritic cell Multiciliated columnar cell of tracheobronchial tree Natural killer cell Pulmonary alveolar type 2 cell Dendritic cell T cell Leukocyte Club cell Regulatory t cell B cell Adventitial cell Non-classical monocyte Lung macrophage Pericyte Endothelial cell of lymphatic vessel Neutrophil Lymphocyte Classical monocyte Fibroblast of lung Mature nk t cell Cd4-positive, alpha-beta t cell Myeloid dendritic cell Intermediate monocyte Cd8-positive, alpha-beta t cell Bronchial smooth muscle cell Smooth muscle cell of the pulmonary artery Pulmonary alveolar type 1 cell Vein endothelial cell Pulmonary neuroendocrine cell Plasma cell Pulmonary interstitial fibroblast Respiratory basal cell

Lung

20-month-old stage and over 18-month-old stage 3-month-old stage

Normal

Female Male

Smart-seq2

Cell

Mus musculus

Cholinergic neuron

Thoracic spinal cord Cervical spinal cord Lumbar spinal cord

8-week-old stage

Normal

Female Male

10x 3' v3

Nucleus

Mus musculus

Notochordal cell Spinal cord interneuron Paraxial cell Neurectodermal cell Gut endothelial cell Splanchnic mesodermal cell Hemangioblast Cardiac valve cell Endodermal cell Primitive red blood cell Midbrain dopaminergic neuron Anterior visceral endoderm cell Premigratory neural crest cell Mesodermal cell Neuroplacodal cell Surface ectodermal cell

Embryo

Theiler stage 14

Normal

Slide-seqv2

Homo sapiens

M cell of gut Intestine goblet cell B cell Enterocyte Precursor cell Mature nk t cell Mesenchymal cell Enteroendocrine cell Stem cell Myeloid leukocyte

Duodenum

50-year-old stage 45-year-old stage

Normal

Female Male

10x 3' v2

Cell

Mus musculus

Microglial cell Mature nk t cell Macrophage Mature microglial cell

Spinal cord

3-6 month-old mature stage

Normal Spinal cord injury

Female

10x 3' v2

Nucleus

Homo sapiens

Lung pericyte Smooth muscle cell Blood vessel smooth muscle cell Smooth muscle cell of the pulmonary artery

Lung Trachea Upper lobe of left lung Lower lobe of left lung Bronchus

66-year-old stage 59-year-old stage 64-year-old stage Seventh decade stage 75-year-old stage 35-year-old stage Sixth decade stage 58-year-old stage 29-year-old stage

Normal

Female Male

10x 3' v2 10x 5' transcription profiling 10x 3' v3

Cell Nucleus

Mus musculus

Oligodendrocyte Astrocyte Obsolete excitatory neuron Oligodendrocyte precursor cell Neuron Obsolete inhibitory neuron

Normal

10x 3' v2

Mus musculus

Notochordal cell Spinal cord interneuron Paraxial cell Neurectodermal cell Gut endothelial cell Splanchnic mesodermal cell Hemangioblast Cardiac valve cell Endodermal cell Primitive red blood cell Midbrain dopaminergic neuron Anterior visceral endoderm cell Premigratory neural crest cell Mesodermal cell Neuroplacodal cell Surface ectodermal cell

Embryo

Theiler stage 14

Normal

Slide-seqv2

Homo sapiens

Dendritic cell B cell Mature nk t cell Erythrocyte Plasma cell Myeloid cell

Blood

74-year-old stage

Covid-19

Female

10x 3' v3

Cell

Mus musculus

Motor neuron Gamma motor neuron Alpha motor neuron

Thoracic spinal cord Cervical spinal cord Lumbar spinal cord

8-week-old stage

Normal

Female Male

10x 3' v3

Nucleus

Microcebus murinus

Natural killer cell Pulmonary alveolar type 2 cell Erythroid lineage cell T cell Regular atrial cardiac myocyte Regular ventricular cardiac myocyte Neuron Pericyte Endothelial cell of lymphatic vessel Neutrophil Mesothelial cell of epicardium Vascular associated smooth muscle cell Endothelial cell Fibroblast Plasma cell Purkinje myocyte Myeloid cell Mesothelial cell Cardiac muscle cell Nodal myocyte

Heart left ventricle Heart right ventricle Cardiac muscle tissue Heart Left cardiac atrium Right cardiac atrium

Post-juvenile adult stage

Normal

Female Male

10x 3' v2 Smart-seq2

Cell